12

General Biology 1
Quarter I - Module 4
The Cell Cycle and Cell
Division

CONTEXTUALIZED LEARNING-INSTRUCTION KIT

SCHOOLS DIVISION OF PUERTO PRINCESA CITY

Science – Senior High School
Contextualized Learning-Instruction Kit (CLIK)
General Biology 1
Quarter I - Module 4: The Cell Cycle and Cell Division
First Edition, 2020

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Published by the Schools Division of Puerto Princesa City

Development Team of the Module

Writer: Brandon C. Manglapus (Palawan NS)
Content Editor: Sheryll C. Saclet (Mandaragat-San Miguel SHS)
Language Editor: Hazel Joyce A. Aquino (Palawan NS)
Reviewer: Rolando A. Taha, Ed D, EPS-Science
Proofreader: Antonieta C. Miguel (Puerto Princesa City NSHS)
Illustrator: Brandon C. Manglapus (Palawan NS)
Layout Artist: Brandon C. Manglapus (Palawan NS)
Management Team: Servillano A. Arzaga, CESO V, SDS
Mabel F. Musa, Ph D, OIC-ASDS
Cyril C. Serador, Ph D, CID Chief
Ronald Brillantes, Division EPS-LRMS Manager
Rolando A. Taha, Ph D, EPS-Science
Eva Joyce C. Presto, PDO II
Rhean Ann A. Navila, Librarian II

Division of Puerto Princesa City-Learning Resource Management Section (LRMS)

Sta. Monica Heights, Bgy. Sta. Monica, Puerto Princesa City
Telephone No.(048) 434 9438
Email Address: puertoprincesa@deped.gov.ph
 12

General Biology 1
Quarter I - Module 4
The Cell Cycle and Cell
Division

This module was collaboratively developed and reviewed by

educators and program supervisors from public schools of the Division of
Puerto Princesa City. We encourage teachers and other education
stakeholders to email their feedback, comments, and recommendations
to the Department of Education, Division of Puerto Princesa City at
puertoprincesa@deped.gov.ph.

We value your feedback and recommendations.

 Introductory Message

For the Teachers:

This learning material is designed to help learners enrich their learning
experiences by answering activities that are meaningful to their lives which can be
done by themselves. A variety of enjoyable tasks are presented.
Activities are provided as formative assessments to check the learner’s
understanding of the lesson. Given the range of learning activities in this package,
teachers are encouraged to freely adapt them to suit their school contexts and
learners’ needs, interests, and abilities.

For the Learners:

This Learning Resource, The Cell Cycle and Cell Division, is developed for
you to enjoy while learning. There are various activities and check-up tests you need
to take.
Take note of the instructions as you journey through this module to have a solid
understanding of what you are expected to accomplish. Carefully read and follow the
instructions to hit what you are expected to do.
Answer keys are provided which you can refer to when checking your answers.
Record your score at the Learner’s Progress Chart and inform your teacher on your
development.
Feel free to use this material and if progress is not evident, you can make use
of it again until the desired passing mark is achieved.

As you read through this module, you will notice the following icons. They will
help you find your way around the module more quickly.

What I Need This will give you an idea of the skills or

competencies you are expected to learn in the
to Know module.

What I Know This part includes an activity that aims to check

what you already know about the lesson to
take.

What’s In This is a brief drill or review to help you link the

current lesson with the previous one.

In this portion, the new lesson will be

What’s New introduced to you in various ways such as a
story, a song, a poem, a problem opener, an
activity, or a situation.
 This section provides a brief discussion of the
What is It lesson. This aims to help you discover and
understand new concepts and skills.

What’s More This comprises activities for independent

practice to solidify your understanding and
skills of the topic.

What I Have This includes questions or blank

Learned sentences/paragraphs to be filled in to process
what you learned from the lesson.

What I Can Do This section provides an activity that will help

you transfer your new knowledge or skill in
real-life situations or concerns.

Assessment This is a task which aims to evaluate your level

of mastery in achieving the learning
competency.

Additional In this portion, another activity will be given to

Activities you to enrich your knowledge or skill of the
lesson learned.

Answer Key This contains answers to all activities in the

module.

References This is a list of all sources used in developing

this module.

Just remember, this module is not intended to replace textbooks and other
existing learning resources but rather to provide an additional alternative that is
contextualized and resilient to education systems that address the challenges of the
current pandemic.

-The Development Team

 This module is packed with notes and essential information covering everything
you need to know about the cell cycle and cell division. You will be able to learn the
different phases of cell cycle and that each phase has its control points that regulates
the process of cell division and reproduction.

There are warm-up and exam-style practice questions for every part to give
you an idea of how well you have already grasped the lesson. This also contains topic-
based questions for focused skills to test your understanding of the concepts of the
lessons under the Most Essential Learning Competencies

Content Standard
The learners demonstrate understanding of the cell cycle and cell
division.
Performance Standard
The learners shall be able to construct a three-dimensional model
of the stages or phases involved in the cell cycle using indigenous
or recyclable materials.
Most Essential Learning Competency
 Characterize the phases of the cell cycle and their control
points.STEM_BIO11/12-Id-f-6
 Describe the stages of mitosis/meiosis given
2n=6.STEM_BIO11/12-Id-f-7
 Explain the significance or applications of mitosis/meiosis.
STEM_BIO11/12-Id-f-9

1
 Directions: These questions will help you think about the lesson
How much
do you already you are about to learn. Choose and circle the letter of the best
know? answer.

1. A stage in the cell cycle where the cell grows fast along with the execution of its
routine metabolic processes- the synthesis of proteins and organelles needed
for cell division is ____________.
A. M phase B. G2 phase C. S phase D. G1 phase
2. Which of the following does mitosis normally accomplish?
A. production of two identical daughter cells
B. production of two unidentical daughter cells
C. production of haploid daughter cells
D. production of four daughter cells
3. What is the cell organelle that directly participates during cell division?
A. mitochondria B. vacuoles C. endoplasmic reticulum D. centrioles
4. This checkpoint ensures that the cell is large enough to divide and that enough
nutrients are available to support the resulting daughter cells?
A. G1 checkpoint B. G2 checkpoint C. S checkpoint D. M checkpoint
5. Which of the following is the correct sequence of mitotic phase?
A. telophase- anaphase- mataphase- prophase
B. prophase- anaphase-metaphase-telophase
C. prophase-metaphase-anaphase-telophase
D. prophase-metaphase-telophase-anaphase
6. If a cell undergoes five mitotic cell division,the total number of chromosomes in
each daughter cells will be equal to_______?
A. 10 B. 16 C. 32 D. 64
7. In which stage of cell division do chromosomes line up in the equatorial plate?
A. prophase B. metaphase C. anaphase D. telophase
8. What is considered as the preparatory stage of the cell where the cell can
become dormant for a long period of time and will only undergo cell division
when the right amount of stimulus is achieved?
A. G0 B. S C. G1 D. interphase
9. The chromosome becomes visible under a light microscope during which stage
of mitosis?
A. prophase B. metaphase C. anaphase D. telophase
10. If the M checkpoint is not cleared, what stage of mitosis will be blocked?
A. Prophase B. Metaphase C. Anaphase D. Telophase
11. The part of meiosis that is similar to mitosis is ______________.
A. meiosis I B. anaphase I C. Meiosis II D. interkinesis
12. Which of the following events does not occur during some stages of interphase?
A. DNA replication C. increase in cell size
B. organelle synthesis D. separation of sister chromatids

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 13. Programmed cell death is known as ____________.
A. Apoptosis B. Oncogene C. Proto-oncogene D.Tumor suppressor gene
14. Which stage of the cell cycle where the cell is preparing for cell division of mitotic
phase?
A. G0 phase B. G1 phase C. S phase D. G2 phase
15. Why do chromosomes coil during mitosis?
A. Allow chromosomes to increase potential energy.
B. Allow chromosomes to move without becoming entagled and breaking
C. Allow chromosomes to fit within nuclear envelope
D. Allow chromosomes to remain attached to each other.

Hello, Learner! This is just a sort of review to get you refreshed! Are you ready?

Activity- Fact or Bluff

Directions: Tell whether the following statement about the phases of cell cycle and its
checkpoint is a Fact or Bluff. Write your answer on the space provided.
_____1. The correct sequence of the cell cycle phase is G1 → S → G2 → M.
_____2. Cell division in prokaryotic and eukaryotic cell is the same.
_____3. The results of DNA replication is duplicated DNA.
_____4. Interphase consists of mitosis and cytokinesis as its stage.
_____5. Brain cells undergo mitotic cell division.
_____6. Unregulated cell division can lead to cancer cells formation.
_____7. Cell spends most its time and life in the G1 /first gap phase.
_____8. Cell cycle is a repeating series of events that describes the life cycle of a cell.
_____9. A mass of abnormal cells is called a tumor.
_____10. The process in which a cell divides is known as mitosis.

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 Source: https://sciencemusicvideos.com/ap-biology/module-12-the-cell-
cycle/regulation-of-the-cell-cycle-interactive-tutorial/
Figure 2- The diagram of the cell cycle

Activity- The Pie of the Cycle

Directions: Familiarize yourself with the diagram and answer the following question.
1. What are the two major stages of the cell cycle?____________________________
2. What are the three substages of the interphase?___________________________
3. When does cytokinesis takes place?____________________________________
4. Why is interphase called the “resting stage of the cell?______________________
5. What is the G0 phase of the cell cycle?__________________________________

4
 Lesson
Cell Cycle and Cell Division
1

Source: https://askabiologist.asu.edu/monarch-life-cycle
https://www.pinterest.ph/pin/474285404499916983/
Figure 1: Life Cycle of Butterfly and Humans is comparable to Cell Cycle

Here we have the representation of the life cycle of two organisms. One picture
depicts the life cycle of a butterfly, one of the humans. Have you ever wonder how this
caterpillar turned into a butterfly or how does a small baby turned into an
adult?Butterflies go through a spectacular life cycle transformations that is from a lowly
worm into a glorious creature that floats on to breeze. Similarly, humans go through
developmental patterns, they go through a series of developmental stages from the
time of birth to the time they mature into an adult and these transformation are mainly
possible, all thanks through the process of cell cycle and cell division. We all know that
each multicellular organisms begins life in the form of a single cell. So how does a
single cell get transformed into large organism?

The Cell cycle is an ordered series of events involving cell growth and cell
division that produces to new daughter cells. Cells on the path to cell division proceed
through a series of precisely timed and carefully regulated stages of growth, DNA
replication, and division that produces two identical cells. The cell cycle has two major
phases, interphase and mitotic phase (Figure 2.) During the interphase, the cell grows
and DNA is replicated. During the mitotic phase, the replicated DNA and cytoplasmic
contents are distributed and the cell divides.

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 Figure 3. The substages of the cell cycle

Interphase

The cell undergoes normal growth processes while also preparing for cell division. In
order for a cell to move from interphase into mitotic phase, many internal and external
conditions must be met. The three stages of interphase are called G1, S, and G2.

G1 Phase (First Gap)

During this time cell grows and more organelles are produced, increasing the volume
of the cytoplasm. The cell is quite active at biochemical level. The cell is accumulating
the building blocks of chromosomal DNA and the associated proteins as well as
accumulating sufficient energy reserves to complete that task of replicating each
chromosomes in the nucleus.

S phase (Synthesis of DNA)

In the S phase, DNA replication can proceed through the mechanisms that result in the
formation of identical DNA molecules-sister chromatids- that are joined at a point by
the centromeric region.The centrosome is duplicated in the S phase and will give rise
to the mitotic spindle that orchestrates the chromosomes during mitosis. At the center
of each animal cell, the centrosomes are associated with a pair of rod-like objects, the
centrioles and help organize cell division.Centrioles are not present in some eukaryotic
species such as plants and most fungi.

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G2 (Second Gap)

In the G2 phase, the cell replenishes its energy stores and synthesize proteins
necessary for chromosome manipulation. Some cell organelles are duplicated and the
cytoskeleton is dismantled to provide resources for mitotic phase. The final preparation
for the mitotic phase must be completed before the cell is able to enter the first stage
of mitosis.

G0 Phase

Not all cells adhere to classic cell cycle patterns in which a newly formed daughter cell
immediately enters the preparatory phases of the interphase closely followed by mitosis.
Cells in G0 phase are not actively preparing to divide.The cell is in quiescent (inactive)
state that occurs when cells exit the cell cycle. Some cells enter G 0 temporarily until
and external signal triggers the onset of G1. Other cells that never or rarely divide, such
as mature cardiac muscle and nerve cells, permanently remain in G0.

Cell cycle checkpoints verify whether all the cellular activities are accurately
completed at each stage of interphase. In eukaryotic cells, there are three major
checkpoints that control the cell cycle process. They are:

1. G1 checkpoint at the G1/S transition

2. G2 checkpoint at the G2/M transition
3. M checkpoint/spindle checkpoint, transition from metaphase and anaphase

G1 checkpoint checks the following:

a. Cell’s size (Does the cell increase its size or large enough for cell
division?)
b. Nutrients (Does the cell have enough reserve energy and nutrients for
cell division?)
c. DNA integrity (Is any part of the DNA damaged?)
d. Molecular signals (Does the cell receives growth factors and other
signals from neighboring cell?)

If the cell does not comply with the following factors, cell cycle will stop
and enters the G0 phase called the resting state. Some cell stays in G0 phase
permanently, while others proceed to divide if the condition of the cell improves.

G2 checkpoint checks the following:

a. DNA integrity (Is any part of the DNA damaged?)
b. DNA replication (Is the DNA replication completed in the S phase?)

If there is an error, the cell will pause at the G2 phase and allow for some
repairs. If the damage is within the DNA, the cell cycle will pause and let the cell
complete the DNA replication or repair it. But if the damage cell is irreparable,
the cell will undergo apoptosis or cell death. It is the self-destruction mechanism
of the cell to ensure that the damaged DNA is not passed on the daughter cells
and also important in preventing cancer. There are some cells that never or

7
 rarely divide like matured cardiac muscle and nerve cell that permanently retain
in G0.

Metaphase checkpoint or Spindle checkpoint occurs at metaphase stage of

mitosis. It is regulated by Anaphase-promoting complex (APC). It checks
whether all chromosomes are properly attached to the spindle fibers and its
alignment at the metaphase plate. If there are mistakes, the cell delays it
anaphase process.

Figure 4- The Cell Cycle Checkpoints

Cancer is the result of the unregulated process of the cell cycle due to the breakdown
of the mechanisms that controls the entire process. It happens during the synthesis
phase, wherein the cell cannot determine the changes in the DNA sequence that code
for the specific regulatory molecules.

Oncogenes are the genes that cause the cell to become cancerous.

Proto-oncogenes are the genes that code for positive regulators during cell cycle.
When these normal genes are altered by mutation it can be an oncogenes leading to
cancer cells formation.

Tumor suppressor genes are healthy normal genes that slow down cell division, helps
to repair DNA mistakes and also cell apoptosis or cell death. It codes for the negative
regulator protein, when activated can prevent the cell from uncontrolled division. But
when tumor suppressor gene does not work properly, cell division will be out of control
and it can also lead to cancer.

Cell Division

There are two different types of cell division in higher living organisms such as
vertebrates. The first type is mitosis and the second type is meiosis. Mitosis is the
normal process of somatic body or body cell division from the cleavage stage up to the
death of an organism.On the other hand , meiosis is a special type of cell division that

8
gives rise to the sperm and egg; hence, not a cycle in itself. Table gives summary of
their differences.

Mitosis Meiosis
Takes place in body/somatic cells Takes place germinal/sex cells
Only one cell division Two cell divisions
Produces two daughter cells that are Produces four cells that are genetically
genetically identical different
Diploid(2N) cells as product Haploid(N) cells as products
Synapses are absent on the chromatids Synapses are present on the chromatids
of homologous chromosomes of homologous chromosomes
Relevant mechanism for growth, tissue Necessary for the production of
repair and replacment of dead or gametes-(egg and sperm cell)
damaged cells

Stages of Mitosis
1. Prophase- coiling and condensation of chromatids into chromosomes.
2. Metaphase- alignment of chromosomes at the equatorial plate.
3. Anaphase- splitting and movement of chromosomes towards the opposite poles.
4. Telophase- nuclear membrane reappears and cytoplasmic division begins.Two
new identical daughter cells are formed.

Source: https://www.shutterstock.com/image-illustration/mitosis-process-where-single-cell-
divides-1581339685
Figure 5-Stages of Mitosis

Karyokinesis and Cytokinesis

Karyokinesis is the process by which the nucleus divides before
cytokinesis.Cytokinesis is the actual division of the cytoplasm that marks the
production of two identical cells.

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Significance of Mitosis
Mitosis is important for development, tissue repair and replenishment, growth, and
continues physiological cycle.The presence of checkpoints is a highly significant
parameter that prevents deleterious consequences of unregulated cell division.

Stages of Meiosis
Meiosis I- reduction division
1. Prophase I-nucleolus and nuclear mebrane starts to disintegrate.Chromosomes
are distinct with sister chromatids fused together by a centromere.Also, the
pairing of homologous chromosomes happens called synapsis.Tetrad is the
term for the four sister chromatid from the pair of chromosomes that are visible
during prophase.Also, crossing over between non-sister chromatids occurs
during this stage. Chiasmata is the point of crossing over, resulting in the
genetic variability of sex cells.
2. Metaphase I- the tetrads line up at the equatorial plane of the cell along with an
increase in the number of the spindle fibers. The spindle fibers facilitate this
movement as it attaches into a kinetochore.
3. Anaphase 1- the homologous chromosomes migrate toward each pole. Half of
the total chromosome number will move to one pole and another half to the other
pole.
4. Telophase 1- the daughter cells completely divide with an equal amount of
chromosomes along with the reappearance of the nuclei.
Interkinesis- this stage pertain to the short pause before entry into meisos II. This is
not similar to interphase, as there is no DNA replication during this stage.
Meisosis II- to complete each process , the cell carrying a haploid number of
chromosomes needs to undergo meiosis II. Note that on this stage, it follows same
event that is taking place in mitotic cell division hence called equational division. The
stages are prophase II,metaphase II, anaphase II and telophase II.

Source: https://www.chegg.com/homework-help/definitions/meiosis-and-mitosis-14
Figure 6. The stages of meiosis

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Significance of Meiosis
The significance of meiosis is for reproduction because this process produces
sperm cell and egg cell, which are the essential for fertilization in mammals. Moreover,
the chromosomal segment exchange is also significant because it alllows a unique
genetic material to transfer to the offspring. This lead to more unique and diverse
individuals genotypically and phenotypically.

Activity 1- Match Me, Match Me!!!

Directions: Match the terms in Column A with the different words related to cell cycle
and checkpoints in Column B. Write your answer on the space provided.

Column A Column B

_____ 1. Cell cycle A. Cell’s series of events

_____ 2. G0 phase B. Chromosome attachment
_____ 3. Interphase C. DNA replication

_____ 4. Metaphase checkpoint D. Cell in quiescent

_____ 5. Synthesis phase E. Resting state
Activity 2- Learning Check A

Directions: Complete the table.

Stages of Mitosis Events in the cell Chromosome Chromosome

number 2N=6 number 2N=46
Prophase

Metaphase

Anaphase

Telophase

Activity 3- Learning Check B

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Directions: Complete the table

Stages of Meiosis Events in the cell Chromosome Chromosome

number 2N=6 number 2N=46
Prophase I

Metaphase I

Anaphase I

Telophase I

Prophase II

Metaphase II

Anaphase II

Telophase II

Activity 1- Modified True or False

Directions: Identify wether the statement is true or false. Write your answer on the
space provided.
_____1.Double stranded chromosomes form during prophase.

_____2.During mitosis, the double stranded chromosomes separate into two.

_____3. Mitosis results in the production of two identical daughter cells.

_____4. During anaphase,the centromere split into two identical daughter cells.

_____5. At telophase, the nuclei of the daughter cells start to reform.

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_____6. In metaphase I, tetrads line up along the equatorial plane of the cell.

_____7. In anaphase I, homologous chromosomes migrate toward each pole.

_____8. DNA replication, takes place during interkinesis.

_____9. Telophase II produces four haploid cells.

_____10. Meiosis II is also called as reduction division.

Activity 2- Essay

Directions: Answer the question briefly but substantially.

1. What is going to happen if the brain cells are not arrested in G0 phase?
______________________________________________________________
______________________________________________________________
2. What are some stimulus that makes some of the cells proceed from G0 phase
to G1?
______________________________________________________________
______________________________________________________________
3. Chemotherapy drug such as vincristine and colchicine disrupt mitosis by binding
to tubulin ( the subunit of microtubules) and interfering with microtubule
assembly and disassembly. Exactly what mitotic structure is targeted by these
drugs and what effect would that have on cell division?
______________________________________________________________
______________________________________________________________
4. Explain how the random alignment of homologous chromosomes during
metaphase I contributes to the variation in gametes produced by meiosis?
______________________________________________________________
______________________________________________________________

Activity- Draw Me

Directions: Creatively illustrate all the different stages of mitosis and meiosis. Draw on
the space provided. Mitosis- PMAT,meiosis- PMAT I and PMAT II.

MITOSIS

13
Prophase Metaphase

Anaphase Telophase

MEIOSIS

Prophase I Metaphase I

Anaphase I Telophase I

14
Prophase II Metaphase II

Anaphase II Telophase II

15
Activity : How sex cells are formed?

Directions: Draw an illustration and explain the process of spermatogenesis and

oogenesis. Compose your explanation on the space provided below.

Spermatogenesis Oogenesis

Congratulations for trying your best in accomplishing this lesson. Try to

share the things you have learned with your classmates and friends.

16
How much have you improved? Check your
improvement index on Answer Key.
Multiple Choice.

Directions: Read each of the following questions carefully. Choose and circle the letter
of the best answer.

1. If a cell undergoes five mitotic cell division,the total number of chromosomes in

each daughter cells will be equal to_______?
A. 10 B. 16 C. 32 D. 64
2. What is the cell organelle that directly participates during cell division?
A. mitochondria B. vacuoles C. endoplasmic reticulum D. centrioles
3. This checkpoint ensures that the cell is large enough to divide and that enough
nutrients are available to support the resulting daughter cells?
A. G1 checkpoint B. G2 checkpoint C. S checkpoint D. M checkpoint
4. Which of the following is the correct sequence of mitotic phase?
A. telophase- anaphase- mataphase- prophase
B. prophase- anaphase-metaphase-telophase
C. prophase-metaphase-anaphase-telophase
D. prophase-metaphase-telophase-anaphase
5. In which stage of cell division do chromosomes line up in the equatorial plate?
A. prophase B. metaphase C. anaphase D. telophase
6. What is considered as the preparatory stage of the cell where the cell can
become dormant for a long period of time and will only undergo cell division
when the right amount of stimulus is achieved?
A. G0 B. S C. G1 D. interphase
7. Why do chromosomes coil during mitosis?
A. Allow chromosomes to increase potential energy.
B. Allow chromosomes to move without becoming entagled and breaking
C. Allow chromosomes to fit within nuclear envelope
D. Allow chromosomes to remain attached to each other
8. The chromosome becomes visible under a light microscope during which stage
of mitosis?
A. prophase B. metaphase C. anaphase D. telophase
9. If the M checkpoint is not cleared, what stage of mitosis will be blocked?
A. Prophase B. Metaphase C. Anaphase D. Telophase
10. A stage in the cell cycle where the cell grows fast along with the execution of
its routine metabolic processes- the synthesis of proteins and organelles needed
for cell division is _____________.
A. M phase B. G2 phase C. S phase D. G1 phase
11. Which of the following does mitosis normally accomplish?
A. production of two identical daughter cells
B. production of two unidentical daughter cells
C. production of haploid daughter cells
D. production of four daughter cells
12. The part of meiosis that is similar to mitosis is ______________.

17
 A. meiosis I B. anaphase I C. Meiosis II D. interkinesis
13. Which of the following events does not occur during some stages of interphase?
A. DNA replication C. increase in cell size
B. organelle synthesis D. separation of sister chromatids
14. Programmed cell death is known as ____________.
A. Apoptosis B. Oncogene C. Proto-oncogene D.Tumor suppressor gene
15. Which stage of the cell cycle where the cell is preparing for cell division of mitotic
phase?
A. G0 phase B. G1 phase C. S phase D. G2 phase

18
 19
What I Know
1.D 2. A 3. D 4. B 5. C 6. B 7. B 8. A 9. A 10. C 11. C 12. D 13. A 14. D 15.B
Whats In
Activity- Fact or Bluff
1.Fact 2.Bluff 3.Fact 4.Bluff 5.Bluff 6.Fact 7. Bluff 8. Fact 9. Fact 10. Fact
What’s New
Activity Learning
Activity-3-Pie Cycle Check B.
1.interphase and the mitotic phase
2.Gap 1, Synthesis,
Note:Answers focused
Gapon2 behavior of chromosomes and student’s reponse may vary.
3. after mitotic phase
4. cell only Chromosome Chromosome number
Stages undergo normalEvents
of Meiosis growthinprocesses
the cell
5.cells are not actively preparing to divide number 2N=46
2N=6
Prophase
What’s MoreI Synapsis,crossing over,nuclear membrane 6 46
Activity 1-Match me Matchdisintegrates
Me!!! etc,
Metaphase
1. A I 2. D 3. E Pair4.ofBhomologous
5. C chromosomes align at 6 46
Activity 2-Learning Check A.the equatorial plate
Note:Answers
Anaphase I focused on behavior Chromsomes move towards
of chromosomes and the
student’s
oppsite reponse may 6vary. 46
Chromosome Chromosome number
Stages of Mitosis polesEvents in the cell
Telophase I number 2N=6
Formation of two new haploid unidentical 2N=46
3 23
daughter cells
Prophase
Prophase II coiling
coilingand
and condensation of
condensationof chromatids 6 into 346 23
chromatids into chromosomes
chromosomes
Metaphase II
Metaphase alignment
alignment of chromosomes
of chromosomes at the equatorial
at the 6 346 23
equatorial
plate. plate.
Anaphase II splitting and movement of chromosomes 3 23
Anaphase splitting and movement of 6 46
towards the opposite poles
chromosomes towards the
Telophase II nuclear membrane reappears and
opposite poles 3 23
cytoplasmic division begins.Formation of
Telophase nuclear membrane reappears and 6 46
four haploid unidentical daughter cells
cytoplasmic division
begins.Formation of two new
diploid identical daughter cells.
What I Have Learned
Activity- Modified True or False
1.True 2. True 3. True 4. True 5. True 6. True 7. True 8. False 9. True 10. False
Activity 2- Essay- answers may vary
Assessment
1.B 2. D 3. B 4. C 5. B 6. A 7.B 8. A 9. C 10. D 11. A 12. C 13. D 14. A 15. D
 References

1. Book

Belardo,Gisselle M.,Yael Avissar et.al General Biology 1 Textbook Vibal

Group Inc.

Dela Pena,Garcilla Pangilinan General Biology 1 Combined Book 1&2 JFS

Publishing Services 2016.

Ching, Johnny A.,General Biology Compendium National Bookstore

Keeton/McFadden.,Elements of Biological Science 3rd Edtion , National

Bookstore, Inc.

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