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Learning Plan Genbio 2 Week 1
Learning Plan Genbio 2 Week 1
SECONDARY DIVISION
SENIOR HIGH SCHOOL UNIT
Academic Year 2019- 2020
PRELIMINARY PART
Topic/ Lesson Name Pedigree Analysis & Sex Linkage and Recombination
Specific Learning Outcomes At the end of the lesson, the learners will be able to conduct the following with 75 % accuracy:
Resources Klug WS, Cummings MR, Spencer CA, Palladino MA. 2012. Essentials of genetics. 8th ed. Benjamin Cummings; 2012. 624 p.
Reece JB, Urry LA, Cain ML, Wasserman SA, Minorsky PV, Jackson RB. 2012. Campbell biology, 9th ed. The Benjamin Cummings
Publishing Co., Inc: 2012. 1464 p.
Bennett RL, Steinhaus KA, Uhrich SB, O’Sullivan CK, Resta RG, Lochner-Doyle D, Markel DS, Vincent V, Hamanishi J.
Recommendations for standardized human pedigree nomenclature. Am J Human Genet. 1995; 56:745-752.
Dates
A. Introduction/ Video Clip Showing: The Other Boleyn Girl Case Study: Three cases using pictures
Motivation
Objective of the Video: To stir the consciousness of the students
on prediction of genotypes and determine their understanding on
the subject matter.
Students are going to watch a video clip which shows a brief
history of the life of King Henry and his pursuit to have a next
heir.
They are going to take note of the events in the clip that struck Misconception: Common misconception is that baldness occurs only in
them. males. Emphasize that baldness does happen in women, although the
frequency is much lower and is therefore rare.
Guide questions to answer:
1. What were your expectations before watching the video clip?
2. How did you feel while and after watching the video clip?
3. What scenes strike you most and why?
B. Delivery of Day 1: Discussion on how to create a Pedigree Analysis. Day 2: Discussion about Sex Linkage and Recombination
instruction
Video Clip: The Pedigree of the Greatest Monarch in the world.
Activity: Make a Pedigree Analysis in the learner’s family using Activity: Thomas Hunt Morgan Experiment
a simple genetic trait.
C. Practice/ Drill 1. Divide learners into groups of four. Case Analysis and Application:
2. Provide copies of four sample pedigrees. (See samples in The last Emperor of Russia, Nicolas II, was married to Empress Alexandra,
Figure 2 at the end of this document.) and they had five children, Olga, Tatiana, Maria, Anastasia, and Alexis.
3. For each pedigree, provide questions for the group to answer Alexis was the only one who was afflicted with hemophilia or the royal
bleeding disease; all other members were normal.
I. Identify the mode of inheritance
Research on this medical condition and determine the mode of
II. Write down the genotypes of specific individuals inheritance.
III. Compute for the probability of having an affected If only Prince Alexis was afflicted with the disease, determine his
offspring genotype.
What could be the genotypes of the Emperor and Empress?
Is it possible that each daughter could have been a carrier?
Expected Expected
Cross
Genotypes Phenotypes
50% dominant:
5. Dd x dd 50% Dd: 50% dd
50% recessive
Prepared: Noted: