PATHOPHYSIOLOGY OF PEDIATRIC COMMUNITY-ACQUIRED PNEUMONIA ( c )
Etiology:
Predisposing factor:
Virus ( Streptococcus Pneumoniae,
* Age (11 months)
S. Aureus)
Precipitating factor:
*Environment
Affected Part:
LUNGS
Aspiration of secretion containing microbes
Failure of defense mechanisms
Invasion of lower respiratory tract
Activation of B cells
Release of antibodies
Antigen-antibody reaction
Antigen antibody complexes adhere to the
mucosal lining
Infection lodges stimulates in the
parenchyma
Lung invasion
Narrowing air passage (pallor, tachypnea)
Leukocytes increased (fever)
Mucosal irritation (cough)
Ineffective airway clearance