INTRODUCING
DENVAX IMMUNOTHERAPY
Your Customised Treatment in Cancer
WHAT ' S I NDS I DE
Intr o d u c t ion............................1
What I s I mmunotherapy?.........2
Abou t D e n vax Cancer
Immu n o t herapy..... ..................4
Diff e r e n c e Between
Chem o t h erapy &
Immu n o t herapy..... ..................6
Mess a g e F rom Director............7
Denv a x I m munotherapy
Vide o s . . . . . ............... .................8
Denv a x S u ccess Stories...........9
How T o B e gin Your Denvax
Trea t m e nt.............. ...............10
Denv a x P a tient Reviews.........11
The D e n v a x Clinics Locations &
Addr e s s e s .............................12
Stay C o n n ected with Denvax..13
ABOUT DENVAX Your Personalised Care in Cancer
Cancer is rising to epidemic proportions. Unless we change the rules of treating cancer, we
cannot make progress in bringing cures.
Cancer prevention is one way of reducing the suffering and mortality in this disease. The other
way is early diagnosis along with a comprehensive treatment plan. For a very long time, we have
seen patients struggle with cancer. We also know cancer needs a different approach in order to
defeat it and that we need to move fast. Thankfully, Immunotherapy has come up in a big way,
bringing not just hope but also cures in this disease.
We, at The Denvax Clinics, have the largest experience of 18+ years in treating various cancers
using "your own cancer-fighting cells" called Dendritic cells. Dendritic cells are potent cells of the
immune system and an important component of Immunotherapy. Denvax is Dendritic cell-based
Immunotherapy, a treatment that harnesses the power of immune system to attack cancer, and it
does this with so much finesse and precision, that there's almost negligible collateral damage
resulting in minimal side effects.
From our clinical experience, we find that Denvax helps most cancer patients in varying degrees.
The majority of the patients respond favorably in some form or the other. A minority may show
no response at all, whereas a small group may even enter into a cure. At The Denvax Clinics, we
keep making endeavors and progress to better the clinical outcomes and help our patients
achieve long and disease-free life."
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IMMUNOTHERAPY
-THE BREAKTHROUGH CANCER TREATMENT
raditionally, we have been treating cancer by attacking it with chemotherapy, radiation, or by removing it
with surgery. For a very long time, physicians have been trying to kill the mutating cells using these "cut
burn and poison" techniques which treats a large number of patients and that's remarkable. Yet, there
remains a large group of patients that do not respond to these treatments, are drug resistant, experience
numerous side effects and have disease of progressive nature.
But now there's a new and effective approach to treat cancer- one that acts on the patient's immune
system, instead of cancer.
Our immune system is the most effective natural defense against any disease. Anything that's not supposed
to be in the body, gets destroyed by the immune system. Cells of the immune system are on constant
patrol to attack and destroy any invaders that make us sick, including cells that mutate to develop into
cancer.
What's the best way to treat cancer?
Cancer is best treated by a multi-modal approach. A multi-modal approach is a comprehensive approach
that includes surgery, radiation, chemotherapy as well as immunotherapy. It also includes alternative and
complementary systems of medicine. Cancer is a difficult-to-treat disease, hence a comprehensive
approach is the best way to treat it. Both cancer and its treatment bring a lot of suffering to the patient. It is
not enough to treat cancer with conventional methods alone, without treating the pain, fatigue, the
depression that comes with it.
A cancer patient needs a complete treatment plan to get rid of cancer and the associated problems.
How does the cancer-killing process take place?
The immune cells such as T cells and Dendritic cells (the key antigen-presenting cells) defend and protect
the body.
The Dendritic cells patrol the body looking for cancer cells and other organisms causing diseases. (They act
as informer cells). The T cells, on the other hand, are the soldiers of the immune system that actually do the
cancer-killing process.
When the Dendritic cell finds a suspicious cell, it sends a specific signal to the T cell to multiply and attack
the suspicious cell. That's how the cancer-killing process takes place.
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The question is why doesn't the immune system fight cancer already?
The answer is, it does try to kill cancer, but cancer evades the immune responses. In other words, cancer
escapes or hides from the immune system shuts down the defences and avoids the fight.
What is cancer immunotherapy, the new breakthrough in science?
Cancer immunotherapy is an approach to defeat cancer, by unmasking cancer, unleashing the power of the
immune system and starting the fight, again. Cancer immunotherapy is often understood as a recent
discovery when in actuality it dates back to antiquity. Despite its long history, it has blossomed into fruition
only in recent years with the advances of multiple forms of treatment, including cancer vaccines, adoptive
cell transfer, chimeric antigen (CAR) T cell, and immune checkpoint inhibitors. The good part is that our
immune system has an amazing capacity for remembering disease-causing agents so immunotherapy
promises a unique opportunity to treat cancer successfully and achieve prolonged remission.
A graphical representation of the cancer-killing process
Can Immunotherapy bring a cure to cancer?
Several studies are showing that Immunotherapy has the power to "cure" cancer, a word used with caution
by Oncologists. The immune system once activated against cancer, not only kills cancer but also memorises
the event of killing. Thus when cancer arises again, the immune system mounts an attack against it, in the
same way, it did the first time, killing the recurrent cancer cells and bringing about a cure in cancer. Unless
we give the immune system a chance to eradicate cancer, we can not be sure of complete recovery or cure.
"The good physician treats the disease,
The great physician treats the patient who has the disease."
-Sir William Osler, 1849-1919 Page 3
DENVAX CANCER
IMMUNOTHERAPY
Let Your Immune System Treat Your Cancer
Denvax is Dendritic Cell Therapy,
- that works to boost immunity against your cancer
DENVAX: DENDRITIC CELL THERAPY FOR CANCER
Dendritic cells are cells of the immune system that help in the fight against cancer.
Denvax is your personalized cancer treatment that involves cancer-fighting dendritic cells. Being
autologous, it is non-toxic and does not interfere with an ongoing treatment plan or the patient’s daily
routine.
Denvax is a treatment for most solid tumors, including lymphoma and multiple myeloma. It can be given
at any stage of the disease. It is targeted therapy and comes under the 4th modality of cancer treatment
called cancer Immunotherapy. The other three are Surgery, Radiation and Chemotherapy.
DENVAX: HOW DOES IT WORK?
In cancer, the immune system fails. As a result, the cells of the immune system fail to recognize the cancer
cells. The immune system doesn’t “see” tumors as foreign or dangerous, and doesn’t mount a strong attack
against them.
Another reason tumors may not stimulate an immune response is that cancer cells develop ways to escape
the immune system.
A dendritic cell is a specialized cell that boosts immune responses in our body, by correcting the failure to
recognize the cancer cell. The activated immune system then circulates throughout the body and destroys
the cancer cells.
DENVAX USES
Denvax is an Adjuvant/Additional treatment plan. It helps to fight cancer by killing the cancer cells. It
works by activating the immune system against cancer. Cancer is best treated by a multi-disciplinary
approach. The other treatment modalities including surgery, radiation and chemotherapy also help to kill
the cancer cells. Denvax adds to this arsenal of killing cancer. It helps to improve quality of life, prolong
life and give better clinical outcomes.
Denvax has little or no conflict with other treatment modalities. Being autologous (self), it is almost non-
toxic and does not interfere with the patient’s ongoing treatment plan or his/her daily routine. In stage IV
patients, it works as palliative therapy, which helps in giving comfort to the patient.
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METHOD OF DENVAX PREPARATION
In this technique, the patient’s own blood cells are taken and transformed into dendritic cells that are
trained to fight cancer cells. These dendritic cells given back to the patient initiate a fight against the
disease at the cellular level and help in stopping cancer.
The first dose manufactured is given to the patient on the 10th day of blood collection. Subsequent doses
are administered at 2- weeks intervals.
HOW TO BEGIN DENVAX TREATMENT?
To begin Denvax treatment, the patient or the attendant is required to contact our office, preferably nearby
the patient's location. The patient is then required to send his reports and a short video, explaining or
showing his/her current clinical status.
The doctor evaluates the patient's clinical condition and may or may not advise Denvax, based on Eligibility
Criteria. Patients willing to take Denvax treatment are required to fill and sign an Informed Consent Form.
The logistics team then works on the collection of blood drawn from the patient’s home. They assign a
trained technical staff to travel to the patient’s location for blood collection.
It takes 8 days to manufacture Denvax. The patient may choose to get the Denvax dose in the comforts of
their home or visit any of the Denvax clinics for receiving the dose. Trained technical staff along with Denvax
dose is sent to the patient's home for administration. The technical staff leaves the patient's home only after
the dose is safely received by the patient. Further doses are administered the same way.
HOW SAFE IS DENVAX?
Denvax has negligible adverse effects or toxicity as compared to chemotherapy. Being an
autologous treatment it is safe and has minimal side effects. Some patients may experience
fever for a day or two after taking Denvax therapy.
Denvax is personalised Denvax is your It is a targeted Being non-toxic, it Denvax is not a Denvax targets
cancer medicine, which additional/adjuva treatment plan. It does not interfere drug; it is a micrometastasis: the
involves cancer-fighting nt treatment plan targets the cancer with the patient's process to disseminated cancer
dendritic cells. cells only, without treatment plan or rejuvenate the cells responsible for
harming the daily routine immune system, the recurrence and
healthy ones specifically relapse of cancer in
against cancer treated patients.
Denvax delays cancer Denvax is given in
THE DENVAX progression and improves
survival
combination with other
modalities of cancer treatment
ADVANTAGE Ease of Denvax manufacturing
and administration
Negligible adverse effects or
toxicity as compared to
Denvax helps prevent relapse chemotherapy
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DIFFERENCE BETWEEN CHEMOTHERAPY
AND IMMUNOTHERAPY
Our immune system is smart and strong, but sometimes that's not
enough to fight a disease like cancer. We know by now, there's a
treatment called immunotherapy that helps use your own immune
system to seek out and destroy cancer. It is different from how
chemotherapy works. Let us find out how:
CHEMOTHERAPY IMMUNOTHERAPY
1. Chemotherapy that attacks tumors 1. Immunotherapy treats you and your
directly. immune system
How does it work?
2. Chemo works as long as the drugs are One, immunotherapy can activate a robust,
in your system, stronger than the normal immune response
Two, it can teach your immune system how to
3. Chemo attacks all rapidly dividing cells, spot cancer cells and destroy them.
both healthy and cancerous, causing some
of the side effects you know, like hair loss 2. Immunotherapy may help your immune
and nausea. system long after treatment ends.
3. With immunotherapy, side effects are
different and can come from an overactive
immune system, and include skin rashes or
diarrhoea. They are less toxic compared to
chemotherapy.
4. With chemo, tumours may shrink
immediately. 4. Immunotherapy can take longer to treat
cancer. Sometimes tumours even appear to
grow before getting smaller.
Immunotherapy is already the standard of care for some
types of cancers, even at advanced stages. Immunotherapy is
changing the paradigm of cancer treatments. More
immunotherapies are available in ongoing clinical trials.
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MESSAGE FROM THE
DIRECTORS
Dr Jamal A Khan, MD
Dr Sharmin Yaqin, MD
Dear Friends,
We, at The Denvax Clinics, strive to Cancer is a dynamic disease process and
ensure we give the best possible keeps evolving. At times, it makes
treatment for our patients suffering from unexpected turns. For this reason, we tailor-
cancer. We understand the pain and made each person's treatment plan, to
suffering patients undergo in this maximise the benefit. Where required, we
disease. Hence, we constantly make advise surgery, radiation, chemotherapy
endeavours to upgrade our system, keep and/or palliative treatment plans. Our aim is
a close contact with our patients and do to optimise the treatment outcomes for each
our best in the treatment we offer. patient.
We try to individualise each treatment Additionally, we ensure that our patient is
plan, best suited for the patient's needs well nourished, free from pain, and living a
and demands. Denvax is a tailor-made life of dignity. We are equipped with a team
treatment and is best used in of doctors for the follow-ups and continued
combination with other treatment patient management, as well as a nursing
modalities. The best approach to treat home for an extra layer of supportive care.
cancer is using and Integrative/Multi-
disciplinary approach, ie using We do our best to ensure we are with you in
conventional methods, like surgery, this struggle. Wishing you the best of health
radiation and chemotherapy, in addition and happiness,
to immunotherapy. This is done to
strengthen the arsenal used in the fight Dr Sharmin Yaqin & Dr Jamal A Khan,
against cancer. Directors,
The Denvax Clinics & Optimum Therapeutics
Pvt. Ltd. India
Email: contact@denvaxindia.com
BUIL D I N G
18 YEARS OF
TRUST
FROM P A TIENTS AL L AROUND
THE W O R LD
Dr Sharmin Yaqin, MD Dr Jamal A Khan, MD
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DENVAX IMMUNOTHERAPY
VIDEOS
Page 8
DENVAX
SUCCESS STORIES
Page 9
DENVAX
HOW TO BEGIN YOUR TREATMENT
Contact The Denvax Clinics Near You
Send the Patient's Reports through Email/Whatsapp.Your Appointment for Video or
In-person consultation will be arranged once the doctors go through your reports.
Consultation with our Team of Doctors:
The patient's condition is assessed during the meeting, and appropriate treatment is
advised in prescription
Once you are ready for the Denvax treatment, blood collection shall be arranged from
your home or one of our Denvax clinics.
Blood collected will reach Denvax Manufacturing Facility and Denvax preparation
starts. This is considered Day 1 of the process.
After 10 days, the Denvax treatment is sent to your location or you receive it in the
Denvax Clinic near you. This will be your first dose.
Once it reaches your home, it is administered to you by one of our trained
technicians. Denvax is given as an IV infusion, under Ondansetrone cover in 20 mts.
Alternately, you can receive it in The Denvax Clinics under the supervision of nursing
staff. (Denvax is safe for home administration, being a biologic, autologous and a
non-toxic treatment.)
Your next dose will be given to you after 15 days from receiving your 1st dose. Your
subsequent doses will be given in the same manner, at -15 days interval.
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DENVAX
PATIENT REVIEWS
Farooqui Azam Firozkhan Khan
Mrs Merajunnisa , 52/F, Oral Cavity Cancer, with Abdominal and Mohd. Fareed, 40/M Cancer Tongue, Mumbai
Peritonial Metastasis, Hyderabad
Denvax is the best hospital for the treatment of cancer in India.
Dear Sir myself Farooqui my wife Mahraj Unnisa taking Denvax Our patient was in the last stage of cancer when we reached
treatment Alhamdolillah after six doses she is feeling herself Denvax but now he is totally fine without operation and without
very fit, weight increased, does not get tired. Mr Abdul helped heavy doses of chemo. May Allah bless him and his
me a lot and he is a very nice helpful man. team. Dr Jamal A. Khan and his team thanks a lot
Dr Bhupendira Singh Syed Habeeb
39/M, Oral Cavity Cancer, Bihar ‘Syed Share, 40/M, Tongue Cancer, Hyderabad
Denvax treatment in Cancer. Myself also doctor and | have so Hello Assalamualaikum Sayaed Sharif ka ilaj doctor Jamal Khan
much relief after taking dendritic cell treatment. |came with ke pass Panjagutta ke Hyderabad chal raha hai
hope here and Dr Jamal did not break it. acha improvmenta raha hai
Faizal Bhari Rajimul Shiekh
‘Sumaiya Bhari 26/F, Synovial Sarcoma, with Lung Metastasis ‘SK Rajibul32/M, Rectal Cancer, Mumba
Maine Dr Jamal ke yaha ilaaj karwaya mujhe fayda hua
Good treatment acche results aate hain Main ab theek hu
Mera abhi Pet scan hona hai
Read More
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THE DENVAX CLINICS, INDIA
Head Office Delhi Denvax Nursing Care Mumbai Office
18 Poorvi Marg Vasant Vihar 84 Poorvi Marg, Vasant Vihar, Shop No. 3,4,5, Mangaljyot
New Delhi 110057 India New Delhi 110057 India Society, Juhu Lane Andheri
West, Mumbai – 400058 India
63 Poorvi Marg Vasant Vihar Phone : 011 41060168,
New Delhi 110057 India 011 40239013 Phone : 022 26241501
Mobile : +91 77385 55971,
Phone : 011 41060168, +91 90041 80211
011 40239013
WhatsApp : +91 9958352455,
+91 7303876727
Hyderabad Office Ahmedabad Office Kolkata Office
5 Ground Floor, MGR Estate, G-1, Span Trade Center, Ground Floor, Block- 1, Sri
Dwarkapuri Colony, Panjagutta, Pritamnagar, Ellisbridge, Ram Nagar Complex, VIP
Hyderabad - 500082 Ahmedabad-380006 India Road, Kolkata – 700052, India
Phone : 040 42012113 Phone : 079 40396660 Phone : +91 8981555444,
+91 03325298007
Lucknow Office Patna Office
Eldeco Elegant, shop No 101, Upper Ground Floor, Surya
Vibhuti khand, Gomtinagar Palace, Boring Patliputra Road
(Opposite Kisan Bazaar) Patna-800013 Bihar
Lucknow 226010.UP.
Tel : 05224304264
Tel : 05224304264
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STAY CONNECTED WITH DENVAX
DENVAX
To know more, visit website Denvaxindia.com
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