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Spermidine cures flies of senior moments

Nature Neuroscience volume 16, pages 1363–1364 (2013)Cite this article

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Gupta et al. report in this issue that, in Drosophila melanogaster, a dietary supplement of spermidine—a polyamine originally isolated from semen—protects against cognitive aging by acting through the autophagic pathway.

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Figure 1: Possible mechanisms for protection against cognitive aging by dietary spermidine.

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Authors and Affiliations

  1. Ronald L. Davis is in the Department of Neuroscience, Scripps Research Institute Florida, Jupiter, Florida, USA.,

    Ronald L Davis

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  1. Ronald L Davis
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Correspondence to Ronald L Davis.

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The author declares no competing financial interests.

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Davis, R. Spermidine cures flies of senior moments. Nat Neurosci 16, 1363–1364 (2013). https://doi.org/10.1038/nn.3518

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