Mode of action
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Recent papers in Mode of action
The present study was undertaken to elucidate the mode of action of methanol extract from aerial parts of L. caulescens (TC-MELc) as spasmolytic agent on in vitro rat ileum test, and investigate the possible antibacterial activity of... more
Polar transport of the phytohormone auxin mediates various processes in plant growth and development, such as apical dominance, tropisms, vascular patterning and axis formation. This view is based largely on the effects of polar auxin... more
Increasing numbers of proteins, nucleic acids and other molecular entities have been explored as therapeutic targets, hundreds of which are targets of approved and clinical trial drugs. Knowledge of these targets and corresponding drugs,... more
Cysteine proteases (falcipains), a papain-family of enzymes of Plasmodium falciparum, are responsible for haemoglobin degradation and thus necessary for its survival during asexual life cycle phase inside the human red blood cells while... more
During the last decade, there has been clear progress in using threshold in risk assessment but its acceptance by scientists is still under debate. Contrary to indirect DNA-damaging agents, DNA-reactive agents have been assumed to have a... more
We outline the most significant features of a research conducted in the last years within three National Research Projects. First, we will discuss some shared, strategic research-choices and guidelines, validated by research results.... more
The production of herbicide resistant plants using molecular and cellular techniques, including mutant selection, cloning, plant transformation and protoplast fusion, is discussed in relation to the mode of action of the herbicide as well... more
The effect of ozone on post-harvest decay of table grapes was studied both with regard to its effectiveness and its possible mode of action. Ozone concentrations fell rapidly upon contact with organic matter and the amount which reacted... more
Rats chronically exposed to acrylonitrile (ACN) have shown a dose-dependent increase in the incidence of astrocytomas in the brain. The mechanism(s) by which ACN induces cancer in rodents has not been established. ACN does not appear to... more
... Francis P. Wong and Wayne F. Wilcox, Department of Plant Pathology, Cornell University, New York Agricultural Experiment Station, Geneva, NY 14456 Plasmopara viticola (Berk. & Curt.) Berl. & Toni., the causal... more