Experience Proteomics Researcher

I was brought up in a small town called Batu Pahat, working my way up to win a Malaysian government scholarship for undergraduate studies which allowed me to enrol in the Imperial College in Biotechnology. I was then offered a research scholarship by the National University of Singapore to work on my PhD project based on the 2-D gel technology, classical biochemical methods and MALDI-TOF MS. Not satisfied, I then acquired skills in mass spectrometry especially FT and Orbitrap, as well as in different types of chromatography which facilitates separation of proteins, peptides and post-translational modifications. I am actively involved in biological and biochemical research in the fields of stem cells and signal transduction. Since 2 years ago, I have also extended my reach to the integration of genomics, transcriptomics and proteomics. From time to time, I am also contacted for reviewing manuscripts submitted to international peer reviewed journals such as Proteomics and Nature Nanotechnology. I am open for all opportunities in bioanalytical research, especially in exploring possible future new directions, questions and applications in biodiversity and their conservation, renewable bio-energy resources, synthetic organisms and synthetic biology. My ORCID profile is available in http://orcid.org/0000-0001-7878-7534. 刘德耀，马来西亚华裔，毕业于伦敦帝国理工学院，又于2005在新加坡国立大学获取博士学位。从事蛋白质组研究逾十年，对飞行时间质谱（TOF）﹑ 离子阱（ion trap）﹑ 傅立叶变换静电场轨道阱（FT Orbitrap）与傅立叶变换离子回旋共振（FT-ICR）的操作以及流程优化有相当的经验，尤其善于利用各种气相离子裂解技术：如碰撞诱导解离（CAD）﹑ 更高能量碰撞诱导解离（HCD）与电子转移解离（ETD）来达到蛋白以及其修饰（磷酸化和泛素化）的测序和定量的目的。现任职于荷兰乌得勒支大学-荷兰国家蛋白质组中心，利用各种分析技术来解决生物及生化课题，尤其在干细胞研究，Wnt 信号转导及整合基因组﹑转录组﹑蛋白质组方面陆续于优质科学期刊如：自然（Nature）﹑ 细胞（Cell）和其子刊等发表论文。对将来的工作重心始终保持开的态度。不过希望能在蛋白质组技术的运用与合成生物学或合成基因组学结合，在环境与物种保育及再生能源等领域做出贡献。