Papers by Abdullah Alkushi
Objective: The purpose of this anatomical study was to explore the morphological, parameters, top... more Objective: The purpose of this anatomical study was to explore the morphological, parameters, topography and diameter of neurovascular pedicles of the semitendinosus muscle. Materials and Methods: The study was conducted on 46 formalin fixed adult human cadaveric lower limbs (20 right and 26 left), at the Department of Human Anatomy, Faculty of Medicine, Umm al Qura University, MakkahSaudi Arabia. The semitendinosus muscle was dissected and studied regarding its origin, insertion, parameters and the number and points of entry of the supplying nerves and diameters of arteries just before entery to the semitendinosus muscle. Results: The mean width of ST fleshy part near origin, at middle and before overlap part were 2.07±0.41, 3.01±0.48, 2.46±0.44 cm respectively. ST muscle thickness mean of fleshy and tendentious parts were 1.45±0.28, 0.39±0.53 cm respectively.1-3neurovascular pedicles entering into the ST muscle. The distance of the entry of neurovascular pedicle to the ST muscle f...
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Honey is a substance produced by bees from the nectar of plants. It is used as a medicine. It is ... more Honey is a substance produced by bees from the nectar of plants. It is used as a medicine. It is known for its biological properties, having antibacterial, antifungal and healing properties. This work was designed to explore the effect of honey extracts on healing of gastric ulcer in experimental rats. Thirty male albino rats (170+5g bw) were used and allocated into 6 equal groups. Group1 (Gp-1) used as negative control while the Gp2-5 were given aspirin orally (200mg/kg bw), and Gp3-5 were treated with honey at doses of 3.5, 7 and 14 ml/kg bw, for seven days respectively. The length of gastric ulcer, volume of gastric juice, total acidity, pH value, and histopathological changes of the stomach were examined. The results revealed that treated orally with honey extracts reduced the length of gastric ulcer, total acidity, volume of gastric juice, and ameliorate histopathological changes caused by Acetylsalicylate. It is concluded that, honey could be used for healing acute gastric ulc...
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Article history: Received 18 December 2016 Accepted 16 February 2017 Available online 25 February... more Article history: Received 18 December 2016 Accepted 16 February 2017 Available online 25 February 2017
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The Gracilis muscle anatomy has been documented by some authors, statistical and observations dat... more The Gracilis muscle anatomy has been documented by some authors, statistical and observations data has been described, but it need re-explored for many metrical and non-metrical parameters, so the purpose of this study was to explore the morphological, parameters, topography and identify the vascular pedicles ofGracilis muscle including their number, caliber,and their locations. Alsothe whole length of Gracilis muscle in relation to the length of the lower limb and gender. The study was conducted on 46 preserved formalin fixed adult human cadaveric lower limbs (26 left and 20 right), The Gracilis muscle was exposed, dissected and studied regarding its origin, insertion, parameters and the number and points of entry of the supplying neurovascular pedicles and diameters of arteries just before entry to the Gracilis muscle.Gracilis muscle mean of total length, fleshy part length, overlap length, tendon length were 46.73±3.91, 21.29±3.57, 11.63±3.45 and13.82±1.52 cm respectively.The mea...
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Pakistan Journal of Nutrition, 2018
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The Professional Medical Journal, 2015
Background: Anterior cruciate ligament (ACL) is commonly injured especiallyin sportsmen. Autograf... more Background: Anterior cruciate ligament (ACL) is commonly injured especiallyin sportsmen. Autografts using tissue from various sources including the quadriceps tendonand patellar ligament are popular but still controversial due to varying degree of success. Themorphological characteristics of the quadriceps tendon and the patellar ligament are of primeimportance for this purpose. Objectives: This cadaveric study was undertaken to evaluate themorphometric characteristics of the quadriceps tendon and patellar ligament as an autograft forACL reconstructive surgery. Study design: Qualitative cadaveric study. Material and methods:The morphometric observations of the quadriceps tendon and patellar ligament on 36 (18 maleand 18 female) adult formalin fixed cadavers were recorded by dissection. The observationsincluded the length, breadth and thickness of the quadriceps tendon and the patellar ligamentand were recorded on both sides separately in the male and female subjects. The data wereta...
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Advances in Reproductive Sciences, 2016
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International Journal of Morphology, 2019
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Pharmacognosy Magazine, 2018
Context: Diabetes mellitus and its increasing effect on endocrine functionality have been widely ... more Context: Diabetes mellitus and its increasing effect on endocrine functionality have been widely observed. Aims: The present study aims at investigating the histopathological changes of splenic cells in diabetic rats. Subjects and Methods: The experiment was conducted on adult male albino rats. They were categorized into four groups: Group I (negative control; fed with standard basal diet [SBD]), Group II (positive control; fed with SBD), Group III (fed on SBD + dose of 50 mg/kg of body weight royal jelly [RJ]) and Group IV were given orally RJ 100 mg/kg of b.wt. The food intake ratio and body weight gain were monitored on a weekly basis. The blood sample and organ tissue samples were collected at the end of feeding and biochemical and immunological analysis was performed for determining the blood glucose level and immune status of the investigated rats. Superoxide dismutase activity was also determined. Results: The results showed increased antioxidant enzymes and lowered glucose levels in diabetic rats fed with RJ. Conclusion: Histopathology tissues indicated moderate to extreme cellular transformations upon treated rats. The histopathological variations in treated rat cells were found to be evident. For this reason, there is likelihood that RJ may have an effect on splenic tissue repair in diabetic rats. Abbreviations used: RJ: Royal jelly; SBD: Standard basal diet; SPSS: Statistical package for the social science; STZ: Streptozotocin; BWG: Body weight gain; SD: Standard deviation.
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International Journal of Pharma and Bio Sciences, 2017
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Journal of Obesity & Weight Loss Therapy, 2016
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Open Journal of Gastroenterology, 2016
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International Journal of Pharma and Bio Sciences, 2017
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Forensic Medicine and Anatomy Research, 2017
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Folia Morphologica, 2017
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International Journal of Anatomy and Research, 2016
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International Journal of Anatomy and Research, 2016
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Life Science Journal
Objectives: This study was designed to evaluate the effect of Zingiber officinale extract on oxid... more Objectives: This study was designed to evaluate the effect of Zingiber officinale extract on oxidative stress and plasma lipid profile in rats through antioxidant enzymatic activities, some selective biochemical analysis and histopathological examination on liver, kidney and stomach in rats through pathological investigation by histpathological and ultra structure lesions. Methods: Thirty male albino rats of body weight 150-200 gm, were divided randomly into 5 equal groups as follow: Group I; normal control, Groups; II & III; received aqueous extract of Zingiber officinale (200 & 400 mg/kg b wt.) respectively. Groups; IV & V received Zingiber officinale ethanol extract (200 & 400 mg/kg b wt.) respectively. The extracts were orally administered daily for 30 days. At the end of experiment period, tissues specimens were obtained from all groups and were fixed in 10% neutral buffered formalin for histopathological and ultra structure examination. Results: GSH level revealed significant ...
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Pharmaceutics
Gut modulation by multi-strain probiotics (MSPs) is considered an effective strategy for treating... more Gut modulation by multi-strain probiotics (MSPs) is considered an effective strategy for treating inflammatory bowel disease (IBD). The combination of nanomaterial-based MSPs can improve their viability and resistance and can allow their targeted release in the gastrointestinal tract to be achieved. Thus, our aim is to investigate the prospective role of MSP integration into nanomaterials (MSPNPs) and the underlying molecular mechanisms supporting their application as an alternative therapy for IBD using a colitis rat model. To induce the colitis model, rats received 5% DSS, and the efficacy of disease progression after oral administration of MSPNPs was assessed by evaluating the severity of clinical signs, inflammatory response, expressions of tight-junction-related genes and NLRP3 inflammasome and caspase-1 genes, microbial composition and histopathological examination of colonic tissues. The oral administration of MSPNPs successfully alleviated the colonic damage induced by DSS a...
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Objectives: To investigate the effect of electrical stimulation of different anatomical variation... more Objectives: To investigate the effect of electrical stimulation of different anatomical variations of sacral surface on early recovery of urinary continence after radical prostatectomy. Methods: Twenty of 53 consecutive patients who underwent prostatectomy by a single surgeon were enrolled in this study. Ten patients were prospectively randomized to two groups; five patients in Sacral foramena stimulation group received postoperative surface electrical stimulation of sacral foramina area while five patients in control group did not received any electrical stimulation. Selection of remaining ten patients depended on sacral hiatus anatomical variations, assessed by plan X-rays. Of the ten patients, five patients with sacral hiatus subtotals were grouped under SHS1 while 5 patients with sacral hiatus totals were grouped as SHS2. Electrical stimulation for each group began 7 days after catheter removal, thrice a week for 8 weeks. Each of the 24 treatment sessions for each group composed of 20 minutes for sacral electrical stimulation. Continence was evaluated at baseline, 4 and 8 weeks using the 24-hour pad test and according to the incontinence section of the International Continence Society questionnaire. Results: After 2 weeks of treatment, the mean leakage weight was comparable between SFS group and SHS1 group while it was significantly lowered in SHS2 as compared to SFS and SHS1 groups. Comparing mean leakage weight at 8 weeks revealed further significant reduction in SHS2 group than in SFS and SHS1 groups. Moreover, percentage of continent patients was highest in SHS2 N. A. ElSawy et al. 2 group after 8 weeks of treatment followed by SHS1, SFS and control respectively. Conclusions: Electrical stimulation of sacral hiatus surface area may provide better stimulation for sacral nerve than sacral foramena surface area and appears to be effective treatment for early recovery of urinary continence after radical prostatectomy.
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Papers by Abdullah Alkushi