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1. Define que es la filosofía. R= es lo que estudia a las causas primeras de los fenómenos de nuestro entorno 2. ¿Qué hecho histórico marca el fin de la edad media? R=la caída de Constantinopla 3. Nombra 3 filósofos renacentistas... more
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      BiologyMedicinePreventionChemicals
To elucidate possible mechanism(s) of carcinogenic action of tetrahydrofuran (THF) that had been demonstrated in previous inhalation studies, groups of male F344 rats and female B6C3F 1 mice were exposed to dynamic atmospheric ...
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      BiologyApoptosisMedicineCell Division
A formal validation study was performed, in order to investigate whether the commercially-available reconstructed human epidermis (RHE) models, EPISKIN®, EpiDerm™ and SkinEthic®, are suitable for in vitro skin absorption testing. The skin... more
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      BiologyMedicineHumansCaffeine
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      Scanning Electron MicroscopyCarbon NanotubesTransmission Electron MicroscopyAerosols
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      ChemistryEnvironmental MonitoringMedicineAerosols
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      ENVIRONMENTAL SCIENCE AND MANAGEMENTPharmacology and pharmaceutical sciences
The mouse local lymph node assay (LLNA) has become the preferred test for evaluating the dermal sensitization potential of chemicals and requirements are now emerging for its use in the evaluation of their formulated products, especially... more
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      European UnionPharmaceutical ChemistryBlock CopolymerHumans
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      GermanyHumansCaffeineTestosterone
It is clear that contact allergens vary substantially with regard to the relative potency with which they are able to induce skin sensitisation. Considerations of potency will in the future become a significant factor in the... more
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      Risk assessmentMedicineEuropean CommissionHumans
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      Risk assessmentAerosolsLongevityPulmonary fibrosis
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      ToxicologyEuropean UnionMedicineAnimals
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      ArchivesCytogeneticsMutagenesisToxicity
Microfine metallic oxides such as titanium dioxide or zinc oxide have been found to be highly protective against harmful UV rays. Because their long-term use could potentially lead to health effects if significant amounts of these... more
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      ChemistryTitaniumPharmaceutical ChemistryMedicine
Pregnant Wistar rats were administered 0, 100, 400 or 1000 mg mono-n-butylamine hydrochloride/kg body weight/day by gavage on days 6 through 15 post coitum (sperm-positive=day 0), or inhaled mono-n-butylamine 0, 17, 50 or 152 ppm... more
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      Free RadicalPregnancyFemaleAnimals
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      AerosolsPregnancyFemaleAnimals