CIR Biomédicas

Long-lasting insecticidal net screens (LLIS) fitted to domestic windows and doors in combination with targeted treatment (TT) of the most productive Aedes aegypti breeding sites were evaluated for their impact on dengue vector indices in a cluster-randomised trial in Mexico between 2011 and 2013. Sequentially over 2 years, LLIS and TT were deployed in 10 treatment clusters (100 houses/cluster) and followed up over 24 months. Cross-sectional surveys quantified infestations of adult mosquitoes, immature stages at baseline (pre-intervention) and in four post-intervention samples at 6-monthly intervals. Identical surveys were carried out in 10 control clusters that received no treatment. LLIS clusters had significantly lower infestations compared to control clusters at 5 and 12 months after installation, as measured by adult (male and female) and pupal-based vector indices. After addition of TT to the intervention houses in intervention clusters, indices remained significantly lower in ...

Dengue prevention efforts rely on control of virus vectors. We investigated use of insecticide-treated screens permanently affixed to windows and doors in Mexico and found that the screens significantly reduced infestations of Aedes aegypti mosquitoes in treated houses. Our findings demonstrate the value of this method for dengue virus vector control.

La enfermedad de Chagas en México es principalmente transmitida por chinches de la familia Triatominae de la cual en el país se cuenta con el registro de 13 especies comprobadas como vectores de Tripanosoma cruzi. En este país no existen registros de susceptibilidad del vector al control químico. Por lo anterior, se determino en una población de Triatoma pallidipennis del estado de Morelos la susceptibilidad a permetrina y deltametrina, mediante la técnica de aplicación tópica (WHO 2005) realizando la determinación de DL 50 y DL 90 para ambos insecticidas. El estado de la población estudiada fue determinado como resistente a deltametrina y a permetrina debido a que exhibió un valor >1000 RR en comparación a una cepa susceptible (Picollo, et al. 2002). Se ha comprobado que la resistencia a piretroides puede estar relacionada a la aplicación sistemática e indiscriminada de plaguicidas y el deterioro de los programas de control; debido a que estos insecticidas son utilizados para el...

Background There is an increased need to mitigate the emergence of insecticide resistance and incorporate new formulations and modes of application to control the urban vector Aedes aegypti. Most research and development of insecticide formulations for the control of Ae. aegypti has focused on their peridomestic use as truck-mounted ULV-sprays or thermal fogs despite the widespread knowledge that most resting Ae. aegypti are found indoors. A recent modification of indoor residual spraying (IRS), termed targeted IRS (TIRS) works by restricting applications to 1.5 m down to the floor and on key Ae. aegypti resting sites (under furniture). TIRS also opens the possibility of evaluating novel residual insecticide formulations currently being developed for malaria IRS. Methods We evaluated the residual efficacy of chlorfenapyr, formulated as Sylando 240SC, for 12 months on free-flying field-derived pyrethroid-resistant Ae. aegypti using a novel experimental house design in Merida, Mexico....