Trehalaza
Изглед
Trehalaza | |||||||||
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Identifikatori | |||||||||
EC broj | 3.2.1.28 | ||||||||
CAS broj | 9025-52-9 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz pregled | ||||||||
BRENDA | BRENDA pristup | ||||||||
ExPASy | NiceZyme pregled | ||||||||
KEGG | KEGG pristup | ||||||||
MetaCyc | metabolički put | ||||||||
PRIAM | profil | ||||||||
Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Trehalaza (EC 3.2.1.28, Alpha,alpha-trehalase) je enzim sa sistematskim imenom alfa,alfa-trehaloza glukohidrolaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- alfa,alfa-trehaloza + H2O beta-D-glukoza + alfa-D-glukoza
Ovaj enzim je anomer-invertujuće glukozidaze koja katalizuje hidrolizu alfa-glukozidne O-veze alfa,alfa-trehaloze.
Reference
[уреди | уреди извор]- ^ Myrbäck, K. and Örtenblad, B. (1937). „Trehalose und Hefe. II. Trehalasewirkung von Hefepräparaten”. Biochem. Z. 291: 61—69.
- ^ Kalf, G.F. & Rieder, S.V. (1958). „The preparation and properties of trehalase”. J. Biol. Chem. 230: 691—698. PMID 13525386.
- ^ Hehre, E.J., Sawai, T., Brewer, C.F., Nakano, M. and Kanda, T. (1982). „Trehalase: stereocomplementary hydrolytic and glucosyl transfer reactions with α- and β-D-glucosyl fluoride”. Biochemistry. 21: 3090—3097. PMID 7104311.
- ^ Mori, H., Lee, J.H., Okuyama, M., Nishimoto, M., Ohguchi, M., Kim, D., Kimura, A. and Chiba, S. (2009). „Catalytic reaction mechanism based on α-secondary deuterium isotope effects in hydrolysis of trehalose by European honeybee trehalase”. Biosci. Biotechnol. Biochem. 73: 2466—2473. PMID 19897915.
Literatura
[уреди | уреди извор]- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
[уреди | уреди извор]- Alpha,alpha-trehalase на US National Library of Medicine Medical Subject Headings (MeSH)