Fosforibozilglicinamid formiltransferaza
Изглед
Fosforibozilglicinamid formiltransferaza | |||||||||
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Identifikatori | |||||||||
EC broj | 2.1.2.2 | ||||||||
CAS broj | 2604945 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz pregled | ||||||||
BRENDA | BRENDA pristup | ||||||||
ExPASy | NiceZyme pregled | ||||||||
KEGG | KEGG pristup | ||||||||
MetaCyc | metabolički put | ||||||||
PRIAM | profil | ||||||||
Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Fosforibozilglicinamid formiltransferaza (EC 2.1.2.2, 2-amino-N-ribozilacetamid 5'-fosfatna transformilaza, GAR formiltransferaza, GAR transformilaza, glicinamid ribonukleotidna transformilaza, GAR TFaza, 5,10-meteniltetrahidrofolat:2-amino-N-ribozilacetamid ribonukleotid transformilaza) je enzim sa sistematskim imenom 10-formiltetrahidrofolat:5'-fosforibozilglicinamid N-formiltransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 10-formiltetrahidrofolat + N1-(5-fosfo-D-ribozil)glicinamid tetrahidrofolat + N2-formil-N1-(5-fosfo-D-ribozil)glicinamid
Reference
[уреди | уреди извор]- ^ Hartman, S.C. & Buchanan, J.M. (1959). „Biosynthesis of the purines. XXVI. The identification of the formyl donors of the transformylation reaction”. J. Biol. Chem. 234: 1812—1816. PMID 13672969.
- ^ Smith, G.K., Benkovic, P.A. and Benkovic, S.J. (1981). „L(-)-10-Formyltetrahydrofolate is the cofactor for glycinamide ribonucleotide transformylase from chicken liver”. Biochemistry. 20: 4034—4036. PMID 7284307.
- ^ Warren, L. & Buchanan, J.M. (1957). „Biosynthesis of the purines. XIX. 2-Amino-N-ribosylacetamide 5′-phosphate (glycinamide ribotide) transformylase”. J. Biol. Chem. 229: 613—626. PMID 13502326.
Literatura
[уреди | уреди извор]- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Vidi još
[уреди | уреди извор]Spoljašnje veze
[уреди | уреди извор]- Phosphoribosylglycinamide+formyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)