GPR156
GPR156 (G protein spregnuti receptor 156) je ljudski gen koji kodira G protein spregnuti receptor iz familije metabotropnih glutamatnih receptora.[1] Po homologiji sekvence ovaj gen je moguća podjedinica GABAB receptora, međutim kad je izražen u ćelijama sam ili sa drugim GABAB podjedinicama, on je manifestuje respons na GABAB ligande. Funkcija ovog gena do sad nije razjašnjena.[2]
| G protein spregnuti receptor 156 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||||
| Simboli | GPR156; GABABL; PGR28 | ||||||||||
| Vanjski ID | OMIM: 610464 MGI: 2653880 HomoloGene: 17683 IUPHAR: GPR156 GeneCards: GPR156 Gene | ||||||||||
| |||||||||||
| Pregled RNK izražavanja | |||||||||||
 | |||||||||||
 | |||||||||||
| podaci | |||||||||||
| Ortolozi | |||||||||||
| Vrsta | Čovek | Miš | |||||||||
| Entrez | 165829 | 239845 | |||||||||
| Ensembl | ENSG00000175697 | ENSMUSG00000046961 | |||||||||
| UniProt | Q8NFN8 | Q6PCP7 | |||||||||
| RefSeq (mRNA) | NM_001168271.1 | NM_153394.2 | |||||||||
| RefSeq (protein) | NP_001161743.1 | NP_700443.2 | |||||||||
| Lokacija (UCSC) |
Chr 3: 119.88 - 120 Mb |
Chr 16: 37.92 - 38.01 Mb | |||||||||
| PubMed pretraga | [1] | [2] | |||||||||
Reference
уреди- ^ „Entrez Gene: GPR156 G protein-coupled receptor 156”.
- ^ Calver AR, Michalovich D, Testa TT, Robbins MJ, Jaillard C, Hill J, Szekeres PG, Charles KJ, Jourdain S, Holbrook JD, Boyfield I, Patel N, Medhurst AD, Pangalos MN (2003). „Molecular cloning and characterisation of a novel GABAB-related G-protein coupled receptor”. Brain Res. Mol. Brain Res. 110 (2): 305—17. PMID 12591167. doi:10.1016/S0169-328X(02)00662-9.
Literatura
уреди- Strausberg RL; Feingold EA; Grouse LH; et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899—903. PMC 139241
. PMID 12477932. doi:10.1073/pnas.242603899. - Calver AR; Michalovich D; Testa TT; et al. (2003). „Molecular cloning and characterisation of a novel GABAB-related G-protein coupled receptor.”. Brain Res. Mol. Brain Res. 110 (2): 305—17. PMID 12591167. doi:10.1016/S0169-328X(02)00662-9.
- Vassilatis DK; Hohmann JG; Zeng H; et al. (2003). „The G protein-coupled receptor repertoires of human and mouse.”. Proc. Natl. Acad. Sci. U.S.A. 100 (8): 4903—8. PMC 153653 . PMID 12679517. doi:10.1073/pnas.0230374100.
- Gerhard DS; Wagner L; Feingold EA; et al. (2004). „The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”. Genome Res. 14 (10B): 2121—7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504.