Pankreasna ribonukleaza
(Preusmjereno sa stranice Ribonukleaza A)
| Pankreasna ribonukleaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| |||||||||
| Pankreasna ribonukleaza I, Human | |||||||||
| Identifikatori | |||||||||
| EC broj | 3.1.27.5 | ||||||||
| CAS broj | 9001-99-4 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Pankreasna ribonukleaza (EC 3.1.27.5, RNaze, RNaze I, RNaze A, pankreasna RNaze, ribonukleaza I, endoribonukleaza I, ribonukleinska fosfataza, alkalinska ribonukleaza, ribonukleaza, gen S glikoproteini, Ceratitis capitata alkalinska ribonukleaza, SLSG glikoproteini, gen S lokus-specifični glikoproteini, ribonukleat 3'-pirimidino-oligonukleotidohidrolaza) je enzim sa sistematskim imenom '.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Endonukleolitičko presecanje do nukleozid 3'-fosfata i 3'-fosfooligonukleotida koji se završavaju sa Cp ili Up uz formiranje 2',3'-cikličnih fosfatnih intermedijera
- ↑ Anfinsen, C.B. and White, F.H., Jr. (1961). „The ribonucleases: occurrence, structure, and properties”. u: Boyer, P.D., Lardy, H. and Myrbäck, K.. The Enzymes. 5 (2nd izd.). New York: Academic Press. str. 95-122.
- ↑ Beard, J.R. and Razzell, W.E. (1964). „Purification of alkaline ribonuclease II from mitochondrial and soluble fractions of liver”. J. Biol. Chem. 239: 4186-4193. PMID 14247667.
- ↑ Cannistraro, V.J. and Kennell, D. (1989). „Purification and characterization of ribonuclease M and mRNA degradation in Escherichia coli”. Int. J. Biochem. 181: 363-370. PMID 2653829.
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.