Papers by Dr. Chandan Kumar
Agricultural Reviews, 2014
Bookmarks Related papers MentionsView impact
Bookmarks Related papers MentionsView impact
Home Health Care Services Quarterly, 2013
The poor maternal health care service utilization among adolescent women remains an intimidating ... more The poor maternal health care service utilization among adolescent women remains an intimidating challenge in Malawi. This study examines the factors associated with the utilization of selected maternal health care services among married adolescent women (aged 15-19 years) using data from the Malawi Demographic and Health Survey, 2010. Maternal age, household economic status, and status of the child were found to be significant factors associated with at least four antenatal care visits; whereas personal barriers, birth order and interval, religion, and ethnic group explain the variation in the utilization of postnatal care within 42 days of delivery.
Bookmarks Related papers MentionsView impact
EC DIABETES AND METABOLIC RESEARCH, 2017
Diabetes is a chronic metabolic disorder and syndrome in which glucose level raises in the blood ... more Diabetes is a chronic metabolic disorder and syndrome in which glucose level raises in the blood (hyperglycemia) due to deficiency or diminished effectiveness of insulin with a strong hereditary basis. It is usually associated with passage of sugar in the urine and initially characterized by a loss of glucose homeostasis with disturbances of carbohydrate, fat and protein metabolism resulting due to defects in insulin secretion , insulin action or both. Diabetes is known to all as slow fatal disease but it is curable one with change in healthy lifestyle. So Diabetes mellitus (DM) is a common major public health problem of today's society in the world affecting millions of people. It is seventh in rank among the leading cause of death and third primarily because of the high rate of cardiovascular disease in people with diabetes. The prevalence of diabetes mellitus is increasing with ageing of the population and lifestyle changes associated with rapid urbanization and westernization due to increased consumption of high calorie and high fat diets and sedentary lifestyle. It is calculated that there are about 150 million people suffering with diabetes at present and this figure may rise to 300 million by 2025. The factors for this steep rise include genetic predisposition, urbanization, ethnicity, insulin resistance and central obesity. Presently, about 40-60% of subjects aged above 40 years in the world are suffering from diabetes mellitus and no fully effective cure is available for the disease. The majority of acute deaths due to insulin deficiency have been reduced due to insulin therapy from 1922, but later on various life threatening side effects have been illustrated. Type-I (insulin-dependent) diabetes, with early age onset, carries higher risk of heart attacks, stroke, nephropathy and peripheral vascular disease. Type-II (insulin non-dependent) diabetes mellitus and associated cardio-vascular diseases (CVD) have reached global epidemic proportions. Insulin resistance individual has commonly increased triglyceride concentrations and elevated total cholesterol concentrations, with increased concentrations of small dense LDL (Low density lipoprotein) and decreased concentrations of HDL (High Density Lipoprotein). The Type-I and Type-II diabetes contribute about 10% and 90% of diabetic population, respectively. The chronic hyperglycemia of diabetes is associated with long-term damage, dysfunction and failure of various organs especially the eyes, kidneys, nerves, heart and blood vessels. Several pathogenic processes are involved in the development of diabetes. These range from autoimmune destruction of the β-cells of the pancreas with consequent insulin deficiency to abnormalities that result in resistance to insulin action. The basis of the abnormalities in carbohydrate, fat and protein metabolism in diabetes is deficient action of insulin on target tissues. Symptoms of marked hyperglycemia include polyuria, polydipsia, weight loss, sometimes with polyphagia and blurred vision. Impairment of growth and susceptibility to certain infections may also accompany chronic hyperglycemia. Acute, life-threatening consequences of diabetes are hyperglycemia with ketoacidosis or nonketotic hyperosmolar syndrome. Long-term complications of diabetes include retinopathy with potential loss of vision; nephropathy leading to renal failure; peripheral neuropathy with risk of foot ulcers, amputation and charcot joints and autonomic neuropathy causing gastrointestinal, genitourinary, cardiovascular symptoms and sexual dysfunction. Patients with diabetes have an increased incidence of atherosclerotic cardiovascular, peripheral vascular and cerebrovascu-lar disease. Hypertension, abnormalities of lipoprotein metabolism and periodontal disease are often found in people with diabetes. The emotional, social impact of diabetes and the demands of therapy may cause significant psychosocial dysfunction in patients and their families. Diabetes and its complications are strongly associated with higher oxidative stress caused by reactive oxygen species (ROS)
Bookmarks Related papers MentionsView impact
ICAR, New Delhi Publication
Bookmarks Related papers MentionsView impact
Adverse effects of herbal products have often been ignored
apparently due to its common use and a... more Adverse effects of herbal products have often been ignored
apparently due to its common use and acceptance over allopathic. Diverse studies on the medicinal properties of Nigella sativa are easily accessible, nevertheless, very few concerns for its toxicity.
Objective: The present study was designed to evaluate cytotoxicity of ethanolic extract of Nigella sativa seed (NSEte) at various dose levels.
Results: The mitotic indices revealed no statistically significant variation. There were no changes in number of micronuclei when compared to control. The mutagenic indices were found insignificantly variable when compared to control.
Conclusion: It was concluded therefore, that the doses of ethanol extract of Nigella sativa seed used in this study are safe and are highly unlikely to have any adverse effect.
Bookmarks Related papers MentionsView impact
Bookmarks Related papers MentionsView impact
Bookmarks Related papers MentionsView impact
Journal of Pharmacognosy and Phytochemistry, 2013; Vol. 2(1): 199-208
Bookmarks Related papers MentionsView impact
The Bioscan, 2010; 2: 423-429
Bookmarks Related papers MentionsView impact
The Bioscan, 2010; 2: 335-341
Bookmarks Related papers MentionsView impact
Wayamba Journal of animal science (e-journal); Vol. 3: ISSN: 2012-578X (WJAS ID 1320125426; 2011-11-01)
Bookmarks Related papers MentionsView impact
Indian Journal of Dairy Science, 2011; 64(1): 33-38.
Bookmarks Related papers MentionsView impact
Biospectra, 2010; 5(1): 23-26
Bookmarks Related papers MentionsView impact
Biospectra, 2010; 5(2): 293-298
Bookmarks Related papers MentionsView impact
Columban Journal of Life Science, 2010; 11(1-2): 37-40
Bookmarks Related papers MentionsView impact
Columban Journal of Life Science, 2010; 11(1-2): 71-73
Bookmarks Related papers MentionsView impact
Uploads
Papers by Dr. Chandan Kumar
apparently due to its common use and acceptance over allopathic. Diverse studies on the medicinal properties of Nigella sativa are easily accessible, nevertheless, very few concerns for its toxicity.
Objective: The present study was designed to evaluate cytotoxicity of ethanolic extract of Nigella sativa seed (NSEte) at various dose levels.
Results: The mitotic indices revealed no statistically significant variation. There were no changes in number of micronuclei when compared to control. The mutagenic indices were found insignificantly variable when compared to control.
Conclusion: It was concluded therefore, that the doses of ethanol extract of Nigella sativa seed used in this study are safe and are highly unlikely to have any adverse effect.
apparently due to its common use and acceptance over allopathic. Diverse studies on the medicinal properties of Nigella sativa are easily accessible, nevertheless, very few concerns for its toxicity.
Objective: The present study was designed to evaluate cytotoxicity of ethanolic extract of Nigella sativa seed (NSEte) at various dose levels.
Results: The mitotic indices revealed no statistically significant variation. There were no changes in number of micronuclei when compared to control. The mutagenic indices were found insignificantly variable when compared to control.
Conclusion: It was concluded therefore, that the doses of ethanol extract of Nigella sativa seed used in this study are safe and are highly unlikely to have any adverse effect.