Chitinase-3-Like Protein 1
"Chitinase-3-Like Protein 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A lectin that binds CHITIN, but lacks chitinase activity. It may be involved in tissue remodeling and cellular responses to the environment, including the response of type 2 HELPER T-CELLS to INFLAMMATION and sensitization to ALLERGENS. Mutations in the CHI3L1 gene are associated with ASTHMA.
| Descriptor ID |
D000071451
|
| MeSH Number(s) |
D08.811.277.450.207.500 D12.776.503.070
|
| Concept/Terms |
Chitinase-3-Like Protein 1- Chitinase-3-Like Protein 1
- Chitinase 3 Like Protein 1
- Cartilage Glycoprotein 39
- Glycoprotein 39, Cartilage
- GP-39 Protein
- GP 39 Protein
- YLK-40 Protein
- YLK 40 Protein
- CHI3L1 Protein
- CGP-39 Protein
- CGP 39 Protein
|
Below are MeSH descriptors whose meaning is more general than "Chitinase-3-Like Protein 1".
Below are MeSH descriptors whose meaning is more specific than "Chitinase-3-Like Protein 1".
This graph shows the total number of publications written about "Chitinase-3-Like Protein 1" by people in this website by year, and whether "Chitinase-3-Like Protein 1" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 3 | 3 |
| 2003 | 0 | 5 | 5 |
| 2004 | 0 | 2 | 2 |
| 2005 | 0 | 2 | 2 |
| 2006 | 0 | 5 | 5 |
| 2007 | 0 | 7 | 7 |
| 2008 | 0 | 5 | 5 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 2 | 2 |
| 2012 | 0 | 2 | 2 |
| 2014 | 0 | 2 | 2 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 2 | 3 |
| 2018 | 2 | 2 | 4 |
| 2019 | 0 | 3 | 3 |
| 2020 | 2 | 4 | 6 |
| 2021 | 2 | 2 | 4 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 3 | 3 |
| 2024 | 1 | 4 | 5 |
| 2025 | 0 | 1 | 1 |
Below are the most recent publications written about "Chitinase-3-Like Protein 1" by people in Profiles.
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Multifaceted Biomarkers Suggest a Similar Profile of CNS Pathology in Relapsing and Progressive MS. Eur J Neurol. 2025 Feb; 32(2):e70052.
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Pharmacodynamic effects of semorinemab on plasma and CSF biomarkers of Alzheimer's disease pathophysiology. Alzheimers Dement. 2024 Dec; 20(12):8855-8866.
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KLOTHO KL-VS heterozygosity is associated with diminished age-related neuroinflammation, neurodegeneration, and synaptic dysfunction in older cognitively unimpaired adults. Alzheimers Dement. 2024 08; 20(8):5347-5356.
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Downstream Biomarker Effects of Gantenerumab or Solanezumab in Dominantly Inherited Alzheimer Disease: The DIAN-TU-001 Randomized Clinical Trial. JAMA Neurol. 2024 Jun 01; 81(6):582-593.
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Pursuing Clinical Predictors and Biomarkers for Progression in ILD: Analysis of the Pulmonary Fibrosis Foundation (PFF) Registry. Lung. 2024 06; 202(3):269-273.
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Association of Plasma YKL-40 With MRI, CSF, and Cognitive Markers of Brain Health and Dementia. Neurology. 2024 Feb 27; 102(4):e208075.
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Diagnostic Utility of Cerebrospinal Fluid Biomarkers in Patients with Rapidly Progressive Dementia. Ann Neurol. 2024 Feb; 95(2):299-313.
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Cerebrospinal fluid biomarkers in the Longitudinal Early-onset Alzheimer's Disease Study. Alzheimers Dement. 2023 11; 19 Suppl 9:S115-S125.
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Urinary Biomarkers of Tubular Health and Risk for Kidney Function Decline or Mortality in Diabetes. Am J Nephrol. 2022; 53(11-12):775-785.
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Sex-dependent neuro-deconvolution analysis of Alzheimer's disease brain transcriptomes according to CHI3L1 expression levels. J Neuroimmunol. 2022 12 15; 373:577977.