"MERRF Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mitochondrial encephalomyopathy characterized clinically by a mixed seizure disorder, myoclonus, progressive ataxia, spasticity, and a mild myopathy. Dysarthria, optic atrophy, growth retardation, deafness, and dementia may also occur. This condition tends to present in childhood and to be transmitted via maternal lineage. Muscle biopsies reveal ragged-red fibers and respiratory chain enzymatic defects. (From Adams et al., Principles of Neurology, 6th ed, p986)
| Descriptor ID |
D017243
|
| MeSH Number(s) |
C05.651.460.620.530 C10.228.140.163.100.545 C10.228.140.490.375.130.650.700 C10.228.140.490.493.063.650.700 C10.668.491.500.500.550 C16.320.565.189.545 C18.452.132.100.545 C18.452.648.189.545 C18.452.660.560.620.530
|
| Concept/Terms |
MERRF Syndrome- MERRF Syndrome
- Syndrome, MERRF
- Myoclonic Epilepsy with Ragged Red Fibers
- Fukuhara Syndrome
- Syndrome, Fukuhara
- MERRF
- Myoclonus with Epilepsy with Ragged Red Fibers
- Myoencephalopathy Ragged-Red Fiber Disease
- Myoencephalopathy Ragged Red Fiber Disease
- Myoclonic Epilepsy Associated with Ragged-Red Fibers
- Myoclonic Epilepsy Associated with Ragged Red Fibers
- Myoclonic Epilepsy with Ragged-Red Fibers
- Fukuhara Disease
- Myoclonic Epilepsy and Ragged Red Fibers
|
Below are MeSH descriptors whose meaning is more general than "MERRF Syndrome".
- Diseases [C]
- Musculoskeletal Diseases [C05]
- Muscular Diseases [C05.651]
- Mitochondrial Myopathies [C05.651.460]
- Mitochondrial Encephalomyopathies [C05.651.460.620]
- MERRF Syndrome [C05.651.460.620.530]
- Nervous System Diseases [C10]
- Central Nervous System Diseases [C10.228]
- Brain Diseases [C10.228.140]
- Brain Diseases, Metabolic [C10.228.140.163]
- Brain Diseases, Metabolic, Inborn [C10.228.140.163.100]
- MERRF Syndrome [C10.228.140.163.100.545]
- Epilepsy [C10.228.140.490]
- Epilepsy, Generalized [C10.228.140.490.375]
- Epilepsies, Myoclonic [C10.228.140.490.375.130]
- Myoclonic Epilepsies, Progressive [C10.228.140.490.375.130.650]
- MERRF Syndrome [C10.228.140.490.375.130.650.700]
- Epileptic Syndromes [C10.228.140.490.493]
- Epilepsies, Myoclonic [C10.228.140.490.493.063]
- Myoclonic Epilepsies, Progressive [C10.228.140.490.493.063.650]
- MERRF Syndrome [C10.228.140.490.493.063.650.700]
- Neuromuscular Diseases [C10.668]
- Muscular Diseases [C10.668.491]
- Mitochondrial Myopathies [C10.668.491.500]
- Mitochondrial Encephalomyopathies [C10.668.491.500.500]
- MERRF Syndrome [C10.668.491.500.500.550]
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
- Genetic Diseases, Inborn [C16.320]
- Metabolism, Inborn Errors [C16.320.565]
- Brain Diseases, Metabolic, Inborn [C16.320.565.189]
- MERRF Syndrome [C16.320.565.189.545]
- Nutritional and Metabolic Diseases [C18]
- Metabolic Diseases [C18.452]
- Brain Diseases, Metabolic [C18.452.132]
- Brain Diseases, Metabolic, Inborn [C18.452.132.100]
- MERRF Syndrome [C18.452.132.100.545]
- Metabolism, Inborn Errors [C18.452.648]
- Brain Diseases, Metabolic, Inborn [C18.452.648.189]
- MERRF Syndrome [C18.452.648.189.545]
- Mitochondrial Diseases [C18.452.660]
- Mitochondrial Myopathies [C18.452.660.560]
- Mitochondrial Encephalomyopathies [C18.452.660.560.620]
- MERRF Syndrome [C18.452.660.560.620.530]
Below are MeSH descriptors whose meaning is more specific than "MERRF Syndrome".
This graph shows the total number of publications written about "MERRF Syndrome" by people in this website by year, and whether "MERRF Syndrome" was a major or minor topic of these publications.
Below are the most recent publications written about "MERRF Syndrome" by people in Profiles.
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Correcting human mitochondrial mutations with targeted RNA import. Proc Natl Acad Sci U S A. 2012 Mar 27; 109(13):4840-5.
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Myocardial flow regulation in people with mitochondrial myopathy, encephalopathy, lactic acidosis, stroke-like episodes/myoclonic epilepsy and ragged red fibers and other mitochondrial syndromes. Coron Artery Dis. 2003 May; 14(3):197-205.
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mtDNA mutations confer cellular sensitivity to oxidant stress that is partially rescued by calcium depletion and cyclosporin A. Biochem Biophys Res Commun. 1997 Oct 09; 239(1):139-45.
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MERRF syndrome with overwhelming lactic acidosis. Pediatr Neurol. 1996 Jan; 14(1):57-61.
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Mitochondrial disorders: analysis of their clinical and imaging characteristics. AJNR Am J Neuroradiol. 1993 Sep-Oct; 14(5):1119-37.