"PC12 Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A CELL LINE derived from a PHEOCHROMOCYTOMA of the rat ADRENAL MEDULLA. PC12 cells stop dividing and undergo terminal differentiation when treated with NERVE GROWTH FACTOR, making the line a useful model system for NERVE CELL differentiation.
| Descriptor ID |
D016716
|
| MeSH Number(s) |
A11.251.210.190.750 A11.251.860.180.750 A11.299.500
|
| Concept/Terms |
PC12 Cells- PC12 Cells
- PC12 Cell
- Pheochromocytoma Cell Line
- Cell Line, Pheochromocytoma
- Cell Lines, Pheochromocytoma
- Pheochromocytoma Cell Lines
|
Below are MeSH descriptors whose meaning is more general than "PC12 Cells".
Below are MeSH descriptors whose meaning is more specific than "PC12 Cells".
This graph shows the total number of publications written about "PC12 Cells" by people in this website by year, and whether "PC12 Cells" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 10 | 11 |
| 1996 | 1 | 17 | 18 |
| 1997 | 1 | 12 | 13 |
| 1998 | 1 | 14 | 15 |
| 1999 | 0 | 11 | 11 |
| 2000 | 0 | 25 | 25 |
| 2001 | 0 | 16 | 16 |
| 2002 | 1 | 20 | 21 |
| 2003 | 1 | 18 | 19 |
| 2004 | 0 | 22 | 22 |
| 2005 | 0 | 15 | 15 |
| 2006 | 0 | 21 | 21 |
| 2007 | 0 | 23 | 23 |
| 2008 | 0 | 18 | 18 |
| 2009 | 0 | 15 | 15 |
| 2010 | 1 | 15 | 16 |
| 2011 | 0 | 15 | 15 |
| 2012 | 0 | 17 | 17 |
| 2013 | 0 | 13 | 13 |
| 2014 | 0 | 11 | 11 |
| 2015 | 0 | 5 | 5 |
| 2016 | 0 | 7 | 7 |
| 2017 | 0 | 4 | 4 |
| 2018 | 0 | 8 | 8 |
| 2019 | 0 | 6 | 6 |
| 2020 | 0 | 6 | 6 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 2 | 2 |
| 2023 | 0 | 2 | 2 |
| 2024 | 0 | 1 | 1 |
Below are the most recent publications written about "PC12 Cells" by people in Profiles.
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Synergy between Laminin-Derived Elastin-like Polypeptides (LELPs) Optimizes Cell Spreading. Biomacromolecules. 2024 07 08; 25(7):4001-4013.
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An LRP1-binding motif in cellular prion protein replicates cell-signaling activities of the full-length protein. JCI Insight. 2023 08 08; 8(15).
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Optimization of thermoresponsive chitosan/β-glycerophosphate hydrogels for injectable neural tissue engineering application. Colloids Surf B Biointerfaces. 2023 Apr; 224:113193.
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Cellular prion protein in human plasma-derived extracellular vesicles promotes neurite outgrowth via the NMDA receptor-LRP1 receptor system. J Biol Chem. 2022 03; 298(3):101642.
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α1-Antitrypsin derived SP16 peptide demonstrates efficacy in rodent models of acute and neuropathic pain. FASEB J. 2022 01; 36(1):e22093.
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Conformational specificity of opioid receptors is determined by subcellular location irrespective of agonist. Elife. 2021 05 20; 10.
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3D In Vitro Neuron on a Chip for Probing Calcium Mechanostimulation. Adv Biosyst. 2020 10; 4(10):e2000080.
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A soluble derivative of PrPC activates cell-signaling and regulates cell physiology through LRP1 and the NMDA receptor. J Biol Chem. 2020 10 09; 295(41):14178-14188.
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Nerve growth factor from Indian Russell's viper venom (RVV-NGFa) shows high affinity binding to TrkA receptor expressed in breast cancer cells: Application of fluorescence labeled RVV-NGFa in the clinical diagnosis of breast cancer. Biochimie. 2020 Sep; 176:31-44.
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Upregulation of RIN3 induces endosomal dysfunction in Alzheimer's disease. Transl Neurodegener. 2020 06 18; 9(1):26.