Paraparesis, Tropical Spastic
"Paraparesis, Tropical Spastic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subacute paralytic myeloneuropathy occurring endemically in tropical areas such as the Caribbean, Colombia, India, and Africa, as well as in the southwestern region of Japan; associated with infection by HUMAN T-CELL LEUKEMIA VIRUS I. Clinical manifestations include a slowly progressive spastic weakness of the legs, increased reflexes, Babinski signs, incontinence, and loss of vibratory and position sensation. On pathologic examination inflammatory, demyelination, and necrotic lesions may be found in the spinal cord. (Adams et al., Principles of Neurology, 6th ed, p1239)
| Descriptor ID |
D015493
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| MeSH Number(s) |
C02.782.815.200.470.710 C10.228.228.618.500 C10.228.854.525.700
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| Concept/Terms |
Paraparesis, Tropical Spastic- Paraparesis, Tropical Spastic
- Parapareses, Tropical Spastic
- Spastic Parapareses, Tropical
- Spastic Paraparesis, Tropical
- Tropical Spastic Parapareses
- HTLV I Associated Myelopathies
- HTLV-I-Associated Myelopathy
- HTLV I Associated Myelopathy
- HTLV-I-Associated Myelopathies
- Myelopathies, HTLV-I-Associated
- Myelopathy, HTLV-I-Associated
- HTLV-I-Associated Myelopathy-Tropical Spastic Paraparesis
- HTLV I Associated Myelopathy Tropical Spastic Paraparesis
- Tropical Spastic Paraparesis
- Myelopathies, HTLV I Associated
- Myelopathy, Htlv-1-Associated
- Htlv-1-Associated Myelopathies
- Htlv-1-Associated Myelopathy
- Myelopathies, Htlv-1-Associated
- Myelopathy, Htlv 1 Associated
- Myelopathy, Human T-Lymphotropic Virus Type 1 Associated
- Myelopathy, Human T Lymphotropic Virus Type 1 Associated
- Paraplegia, Tropical Spastic
- Paraplegias, Tropical Spastic
- Spastic Paraplegia, Tropical
- Spastic Paraplegias, Tropical
- Tropical Spastic Paraplegia
- Tropical Spastic Paraplegias
- Familial Spastic Paraparesis, Htlv-1-Associated
- Familial Spastic Paraparesis, Htlv 1 Associated
- Human T-Lymphotropic Virus Type 1 Associated Myelopathy
- Human T Lymphotropic Virus Type 1 Associated Myelopathy
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Below are MeSH descriptors whose meaning is more general than "Paraparesis, Tropical Spastic".
Below are MeSH descriptors whose meaning is more specific than "Paraparesis, Tropical Spastic".
This graph shows the total number of publications written about "Paraparesis, Tropical Spastic" by people in this website by year, and whether "Paraparesis, Tropical Spastic" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 1999 | 1 | 1 | 2 |
| 2001 | 0 | 1 | 1 |
| 2003 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 1 | 2 |
| 2009 | 1 | 0 | 1 |
| 2010 | 2 | 0 | 2 |
| 2016 | 1 | 1 | 2 |
| 2017 | 2 | 0 | 2 |
| 2018 | 0 | 2 | 2 |
| 2019 | 2 | 0 | 2 |
| 2020 | 4 | 1 | 5 |
| 2022 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
Below are the most recent publications written about "Paraparesis, Tropical Spastic" by people in Profiles.
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Dendritic Cells Pulsed with HAM/TSP Exosomes Sensitize CD4 T Cells to Enhance HTLV-1 Infection, Induce Helper T-Cell Polarization, and Decrease Cytotoxic T-Cell Response. Viruses. 2024 Sep 10; 16(9).
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Efficacy of Corticosteroid Therapy for HTLV-1-Associated Myelopathy: A Randomized Controlled Trial (HAMLET-P). Viruses. 2022 01 12; 14(1).
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Effectiveness and safety of non-tumor necrosis factor inhibitor therapy for anti-human T-cell leukemia virus type 1 antibody-positive rheumatoid arthritis. Mod Rheumatol. 2021 Sep; 31(5):972-978.
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HLA-B*35 as a new marker for susceptibility to human T-cell lymphotropic virus type 1 (HTLV-1) Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP) in patients living in Argentina. Retrovirology. 2020 09 03; 17(1):29.
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Creation and validation of a bladder dysfunction symptom score for HTLV-1-associated myelopathy/tropical spastic paraparesis. Orphanet J Rare Dis. 2020 07 03; 15(1):175.
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Mortality and risk of progression to adult T cell leukemia/lymphoma in HTLV-1-associated myelopathy/tropical spastic paraparesis. Proc Natl Acad Sci U S A. 2020 05 26; 117(21):11685-11691.
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Acupuncture in the treatment of HTLV-I-associated myelopathy / tropical spastic Paraparesis. J Neurovirol. 2020 06; 26(3):415-421.
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Use of cerebrospinal fluid CXCL10 and neopterin as biomarkers in HTLV-1-associated myelopathy/tropical spastic paraparesis treated with steroids. J Neurol Neurosurg Psychiatry. 2020 03; 91(3):321-323.
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Real-world clinical course of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) in Japan. Orphanet J Rare Dis. 2019 10 21; 14(1):227.
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Brief Report: Attenuated Effectiveness of Tumor Necrosis Factor Inhibitors for Anti-Human T Lymphotropic Virus Type I Antibody-Positive Rheumatoid Arthritis. Arthritis Rheumatol. 2018 07; 70(7):1014-1021.