"Muscular Atrophy, Spinal" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of disorders marked by progressive degeneration of motor neurons in the spinal cord resulting in weakness and muscular atrophy, usually without evidence of injury to the corticospinal tracts. Diseases in this category include Werdnig-Hoffmann disease and later onset SPINAL MUSCULAR ATROPHIES OF CHILDHOOD, most of which are hereditary. (Adams et al., Principles of Neurology, 6th ed, p1089)
| Descriptor ID |
D009134
|
| MeSH Number(s) |
C10.228.854.468 C10.574.562.500 C10.668.467.500
|
| Concept/Terms |
Muscular Atrophy, Spinal- Muscular Atrophy, Spinal
- Atrophy, Spinal Muscular
- Spinal Amyotrophy
- Amyotrophies, Spinal
- Amyotrophy, Spinal
- Spinal Amyotrophies
- Spinal Muscular Atrophy
Hereditary Motor Neuronopathy- Hereditary Motor Neuronopathy
- Hereditary Motor Neuronopathies
- Motor Neuronopathies, Hereditary
- Motor Neuronopathy, Hereditary
- Neuronopathies, Hereditary Motor
- Neuronopathy, Hereditary Motor
Scapuloperoneal Form of Spinal Muscular Atrophy- Scapuloperoneal Form of Spinal Muscular Atrophy
- Spinal Muscular Atrophy, Scapuloperoneal Form
- Spinal Muscular Atrophy, Scapuloperoneal
- Amyotrophy, Neurogenic Scapuloperoneal, New England Type
- Scapuloperoneal Spinal Muscular Atrophy
Progressive Muscular Atrophy- Progressive Muscular Atrophy
- Atrophies, Progressive Muscular
- Atrophy, Progressive Muscular
- Muscular Atrophies, Progressive
- Muscular Atrophy, Progressive
- Progressive Muscular Atrophies
- Progressive Myelopathic Muscular Atrophy
- Myelopathic Muscular Atrophy, Progressive
Bulbospinal Neuronopathy- Bulbospinal Neuronopathy
- Bulbospinal Neuronopathies
- Neuronopathies, Bulbospinal
- Neuronopathy, Bulbospinal
Myelopathic Muscular Atrophy- Myelopathic Muscular Atrophy
- Atrophy, Myelopathic Muscular
- Muscular Atrophy, Myelopathic
- Adult-Onset Spinal Muscular Atrophy
- Adult Onset Spinal Muscular Atrophy
- Muscular Atrophy, Adult Spinal
- Adult Spinal Muscular Atrophy
|
Below are MeSH descriptors whose meaning is more general than "Muscular Atrophy, Spinal".
Below are MeSH descriptors whose meaning is more specific than "Muscular Atrophy, Spinal".
This graph shows the total number of publications written about "Muscular Atrophy, Spinal" by people in this website by year, and whether "Muscular Atrophy, Spinal" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 2 | 0 | 2 |
| 1998 | 2 | 0 | 2 |
| 1999 | 1 | 0 | 1 |
| 2004 | 2 | 0 | 2 |
| 2005 | 5 | 0 | 5 |
| 2006 | 1 | 1 | 2 |
| 2007 | 0 | 1 | 1 |
| 2008 | 2 | 0 | 2 |
| 2009 | 2 | 1 | 3 |
| 2011 | 2 | 0 | 2 |
| 2012 | 2 | 4 | 6 |
| 2013 | 1 | 2 | 3 |
| 2014 | 2 | 0 | 2 |
| 2015 | 2 | 0 | 2 |
| 2016 | 1 | 1 | 2 |
| 2017 | 6 | 1 | 7 |
| 2018 | 6 | 0 | 6 |
| 2019 | 4 | 0 | 4 |
| 2020 | 8 | 1 | 9 |
| 2021 | 2 | 0 | 2 |
| 2022 | 5 | 0 | 5 |
| 2023 | 5 | 0 | 5 |
| 2024 | 4 | 1 | 5 |
Below are the most recent publications written about "Muscular Atrophy, Spinal" by people in Profiles.
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Improvement of TaC9-ABE mediated correction of human SMN2 gene. Biotechnol Bioeng. 2024 Oct; 121(10):3059-3067.
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Living with spinal muscular atrophy while working in critical care. Lancet Respir Med. 2024 Jul; 12(7):510-512.
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Modeling Spinal Muscular Atrophy in Zebrafish: Current Advances and Future Perspectives. Int J Mol Sci. 2024 Feb 06; 25(4).
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Mutation corrections in spinal muscular atrophy. Nat Biomed Eng. 2024 Feb; 8(2):111-113.
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Real-World Outcomes in Patients with Spinal Muscular Atrophy Treated with Onasemnogene Abeparvovec Monotherapy: Findings from the RESTORE Registry. J Neuromuscul Dis. 2024; 11(2):425-442.
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Daily Quantity and Kinematic Characteristics of Leg Movement in a Child With SMA (2 Copies SMN2). Pediatr Phys Ther. 2023 10 01; 35(4):486-492.
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Spinal Muscular Atrophy: A (Now) Treatable Neurodegenerative Disease. Pediatr Clin North Am. 2023 10; 70(5):963-977.
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Plastin 3 rescues BDNF-TrkB signaling in spinal muscular atrophy. J Cell Biol. 2023 03 06; 222(3).
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Newbornscreening SMA - From Pilot Project to Nationwide Screening in Germany. J Neuromuscul Dis. 2023; 10(1):55-65.
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Intrathecal Onasemnogene Abeparvovec for Sitting, Nonambulatory Patients with Spinal Muscular Atrophy: Phase I Ascending-Dose Study (STRONG). J Neuromuscul Dis. 2023; 10(3):389-404.