"Lactones" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cyclic esters of hydroxy carboxylic acids, containing a 1-oxacycloalkan-2-one structure. Large cyclic lactones of over a dozen atoms are MACROLIDES.
| Descriptor ID |
D007783
|
| MeSH Number(s) |
D02.540
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Lactones".
Below are MeSH descriptors whose meaning is more specific than "Lactones".
This graph shows the total number of publications written about "Lactones" by people in this website by year, and whether "Lactones" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 3 | 3 | 6 |
| 1997 | 2 | 0 | 2 |
| 1998 | 3 | 0 | 3 |
| 1999 | 2 | 3 | 5 |
| 2000 | 3 | 0 | 3 |
| 2001 | 2 | 1 | 3 |
| 2002 | 5 | 2 | 7 |
| 2003 | 8 | 1 | 9 |
| 2004 | 4 | 4 | 8 |
| 2005 | 9 | 8 | 17 |
| 2006 | 8 | 4 | 12 |
| 2007 | 4 | 2 | 6 |
| 2008 | 7 | 4 | 11 |
| 2009 | 6 | 4 | 10 |
| 2010 | 8 | 4 | 12 |
| 2011 | 7 | 4 | 11 |
| 2012 | 5 | 9 | 14 |
| 2013 | 5 | 4 | 9 |
| 2014 | 8 | 1 | 9 |
| 2015 | 4 | 2 | 6 |
| 2016 | 3 | 4 | 7 |
| 2017 | 2 | 2 | 4 |
| 2018 | 4 | 1 | 5 |
| 2019 | 4 | 1 | 5 |
| 2020 | 3 | 3 | 6 |
| 2021 | 2 | 2 | 4 |
| 2022 | 0 | 2 | 2 |
| 2023 | 1 | 2 | 3 |
| 2024 | 2 | 1 | 3 |
Below are the most recent publications written about "Lactones" by people in Profiles.
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Marizomib for patients with newly diagnosed glioblastoma: A randomized phase 3 trial. Neuro Oncol. 2024 Sep 05; 26(9):1670-1682.
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A sustainable bioprocess technology for producing food-flavour (+)-γ-decalactone from castor oil-derived ricinoleic acid using enzymatic activity of Candida parapsilosis: Scale-up optimization and purification using novel composite. J Biotechnol. 2024 Sep 20; 393:17-30.
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From UK-2A to florylpicoxamid: Active learning to identify a mimic of a macrocyclic natural product. J Comput Aided Mol Des. 2024 Apr 17; 38(1):19.
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Synthase-selected sorting approach identifies a beta-lactone synthase in a nudibranch symbiotic bacterium. Microbiome. 2023 06 13; 11(1):130.
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Hyperpolarized δ-[1- 13C]gluconolactone imaging visualizes response to TERT or GABPB1 targeting therapy for glioblastoma. Sci Rep. 2023 03 30; 13(1):5190.
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Maize resistance to witchweed through changes in strigolactone biosynthesis. Science. 2023 01 06; 379(6627):94-99.
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Clinical pharmacokinetics of kavalactones after oral dosing of standardized kava extract in healthy volunteers. J Ethnopharmacol. 2022 Oct 28; 297:115514.
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Enzymatic assembly of the salinosporamide γ-lactam-β-lactone anticancer warhead. Nat Chem Biol. 2022 05; 18(5):538-546.
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aPC/PAR1 confers endothelial anti-apoptotic activity via a discrete, β-arrestin-2-mediated SphK1-S1PR1-Akt signaling axis. Proc Natl Acad Sci U S A. 2021 12 07; 118(49).
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Characterization of Different Forms of Kava (Piper methysticum) Products by UPLC-MS/MS. Planta Med. 2022 Nov; 88(14):1348-1359.