"Hyperinsulinism" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A syndrome with excessively high INSULIN levels in the BLOOD. It may cause HYPOGLYCEMIA. Etiology of hyperinsulinism varies, including hypersecretion of a beta cell tumor (INSULINOMA); autoantibodies against insulin (INSULIN ANTIBODIES); defective insulin receptor (INSULIN RESISTANCE); or overuse of exogenous insulin or HYPOGLYCEMIC AGENTS.
| Descriptor ID |
D006946
|
| MeSH Number(s) |
C18.452.394.968
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Hyperinsulinism".
Below are MeSH descriptors whose meaning is more specific than "Hyperinsulinism".
This graph shows the total number of publications written about "Hyperinsulinism" by people in this website by year, and whether "Hyperinsulinism" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1996 | 0 | 1 | 1 |
| 1997 | 3 | 1 | 4 |
| 1998 | 5 | 2 | 7 |
| 1999 | 2 | 3 | 5 |
| 2000 | 3 | 3 | 6 |
| 2001 | 2 | 7 | 9 |
| 2002 | 3 | 3 | 6 |
| 2003 | 1 | 5 | 6 |
| 2004 | 4 | 2 | 6 |
| 2005 | 2 | 3 | 5 |
| 2006 | 7 | 7 | 14 |
| 2007 | 3 | 5 | 8 |
| 2008 | 2 | 4 | 6 |
| 2009 | 0 | 1 | 1 |
| 2010 | 4 | 2 | 6 |
| 2011 | 4 | 1 | 5 |
| 2012 | 2 | 2 | 4 |
| 2013 | 1 | 4 | 5 |
| 2014 | 2 | 2 | 4 |
| 2015 | 1 | 1 | 2 |
| 2016 | 0 | 4 | 4 |
| 2017 | 3 | 5 | 8 |
| 2018 | 3 | 1 | 4 |
| 2019 | 5 | 3 | 8 |
| 2020 | 1 | 1 | 2 |
| 2021 | 4 | 1 | 5 |
| 2022 | 6 | 0 | 6 |
| 2023 | 2 | 0 | 2 |
| 2024 | 1 | 0 | 1 |
Below are the most recent publications written about "Hyperinsulinism" by people in Profiles.
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Discovery and Clinical Proof-of-Concept of RLY-2608, a First-in-Class Mutant-Selective Allosteric PI3Kα Inhibitor That Decouples Antitumor Activity from Hyperinsulinemia. Cancer Discov. 2024 Feb 08; 14(2):240-257.
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Association of dietary insulinemic and inflammatory potential with risk of liver cancer and chronic liver disease mortality in postmenopausal women: a prospective cohort study. Am J Clin Nutr. 2023 09; 118(3):530-537.
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MBOAT7-driven lysophosphatidylinositol acylation in adipocytes contributes to systemic glucose homeostasis. J Lipid Res. 2023 04; 64(4):100349.
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Postdiagnostic Inflammatory, Hyperinsulinemic, and Insulin-Resistant Diets and Lifestyles and the Risk of Prostate Cancer Progression and Mortality. Cancer Epidemiol Biomarkers Prev. 2022 09 02; 31(9):1760-1768.
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Hyperinsulinemia Is Highly Associated With Markers of Hepatocytic Senescence in Two Independent Cohorts. Diabetes. 2022 09 01; 71(9):1929-1936.
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Rapamycin/metformin co-treatment normalizes insulin sensitivity and reduces complications of metabolic syndrome in type 2 diabetic mice. Aging Cell. 2022 09; 21(9):e13666.
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Face-sparing Congenital Generalized Lipodystrophy Type 1 Associated With Nonclassical Congenital Adrenal Hyperplasia. J Clin Endocrinol Metab. 2022 08 18; 107(9):2433-2438.
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A low n-6 to n-3 polyunsaturated fatty acid ratio diet improves hyperinsulinaemia by restoring insulin clearance in obese youth. Diabetes Obes Metab. 2022 07; 24(7):1267-1276.
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Experimentally Induced Hyperinsulinemia Fails to Induce Polycystic Ovary Syndrome-like Traits in Female Rhesus Macaques. Int J Mol Sci. 2022 Feb 27; 23(5).
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The Physiology of Insulin Clearance. Int J Mol Sci. 2022 Feb 05; 23(3).