"Glutarates" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Derivatives of glutaric acid (the structural formula (COO-)2C3H6), including its salts and esters.
Descriptor ID |
D005977
|
MeSH Number(s) |
D02.241.081.337.351
|
Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Glutarates".
Below are MeSH descriptors whose meaning is more specific than "Glutarates".
This graph shows the total number of publications written about "Glutarates" by people in this website by year, and whether "Glutarates" was a major or minor topic of these publications.
View timeline visualization
Year | Major Topic | Minor Topic | Total |
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1995 | 2 | 0 | 2 |
1996 | 1 | 1 | 2 |
1999 | 2 | 0 | 2 |
2001 | 1 | 0 | 1 |
2005 | 2 | 1 | 3 |
2006 | 2 | 1 | 3 |
2007 | 1 | 0 | 1 |
2008 | 1 | 0 | 1 |
2009 | 1 | 0 | 1 |
2010 | 4 | 0 | 4 |
2011 | 2 | 0 | 2 |
2012 | 2 | 1 | 3 |
2013 | 1 | 2 | 3 |
2014 | 2 | 1 | 3 |
2015 | 5 | 2 | 7 |
2016 | 2 | 3 | 5 |
2017 | 2 | 4 | 6 |
2018 | 5 | 1 | 6 |
2019 | 1 | 0 | 1 |
2020 | 2 | 1 | 3 |
2021 | 2 | 0 | 2 |
2022 | 0 | 3 | 3 |
2023 | 0 | 1 | 1 |
2024 | 2 | 0 | 2 |
Below are the most recent publications written about "Glutarates" by people in Profiles.
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Autophagic signaling promotes systems-wide remodeling in skeletal muscle upon oncometabolic stress by D2-HG. Mol Metab. 2024 Aug; 86:101969.
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D-2-HG Inhibits IDH1mut Glioma Growth via FTO Inhibition and Resultant m6A Hypermethylation. Cancer Res Commun. 2024 03 22; 4(3):876-894.
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(R)-2-Hydroxyglutarate Inhibits KDM5 Histone Lysine Demethylases to Drive Transformation in IDH-Mutant Cancers. Cancer Discov. 2023 06 02; 13(6):1478-1497.
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Spectroscopic imaging of D-2-hydroxyglutarate and other metabolites in pre-surgical patients with IDH-mutant lower-grade gliomas. J Neurooncol. 2022 Aug; 159(1):43-52.
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Inhibition of D-2HG leads to upregulation of a proinflammatory gene signature in a novel HLA-A2/HLA-DR1 transgenic mouse model of IDH1R132H-expressing glioma. J Immunother Cancer. 2022 05; 10(5).
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A feedback loop engaging propionate catabolism intermediates controls mitochondrial morphology. Nat Cell Biol. 2022 04; 24(4):526-537.
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Inborn errors of metabolism associated with 3-methylglutaconic aciduria. Clin Chim Acta. 2021 Nov; 522:96-104.
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Low pH Facilitates Heterodimerization of Mutant Isocitrate Dehydrogenase IDH1-R132H and Promotes Production of 2-Hydroxyglutarate. Biochemistry. 2021 06 29; 60(25):1983-1994.
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R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m6A/PFKP/LDHB axis. Mol Cell. 2021 03 04; 81(5):922-939.e9.
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Neuroprotective effects of a dendrimer-based glutamate carboxypeptidase inhibitor on superoxide dismutase transgenic mice after neonatal hypoxic-ischemic brain injury. Neurobiol Dis. 2021 01; 148:105201.