"Epoxide Hydrolases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that catalyze reversibly the formation of an epoxide or arene oxide from a glycol or aromatic diol, respectively.
| Descriptor ID |
D004851
|
| MeSH Number(s) |
D08.811.277.340
|
| Concept/Terms |
Epoxide Hydrolases- Epoxide Hydrolases
- Hydrolases, Epoxide
- Epoxide Hydratases
- Hydratases, Epoxide
- Epoxide Hydrases
- Hydrases, Epoxide
9,10-Epoxypalmitic Acid Hydrase- 9,10-Epoxypalmitic Acid Hydrase
- 9,10 Epoxypalmitic Acid Hydrase
- Acid Hydrase, 9,10-Epoxypalmitic
- Hydrase, 9,10-Epoxypalmitic Acid
|
Below are MeSH descriptors whose meaning is more general than "Epoxide Hydrolases".
Below are MeSH descriptors whose meaning is more specific than "Epoxide Hydrolases".
This graph shows the total number of publications written about "Epoxide Hydrolases" by people in this website by year, and whether "Epoxide Hydrolases" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 6 | 1 | 7 |
| 1996 | 2 | 1 | 3 |
| 1997 | 3 | 0 | 3 |
| 1998 | 2 | 0 | 2 |
| 1999 | 6 | 1 | 7 |
| 2000 | 9 | 1 | 10 |
| 2001 | 5 | 3 | 8 |
| 2002 | 5 | 0 | 5 |
| 2003 | 6 | 0 | 6 |
| 2004 | 8 | 1 | 9 |
| 2005 | 17 | 1 | 18 |
| 2006 | 15 | 1 | 16 |
| 2007 | 12 | 1 | 13 |
| 2008 | 15 | 1 | 16 |
| 2009 | 18 | 1 | 19 |
| 2010 | 16 | 2 | 18 |
| 2011 | 19 | 5 | 24 |
| 2012 | 33 | 0 | 33 |
| 2013 | 20 | 5 | 25 |
| 2014 | 21 | 4 | 25 |
| 2015 | 25 | 3 | 28 |
| 2016 | 17 | 1 | 18 |
| 2017 | 21 | 5 | 26 |
| 2018 | 19 | 4 | 23 |
| 2019 | 21 | 3 | 24 |
| 2020 | 30 | 11 | 41 |
| 2021 | 19 | 8 | 27 |
| 2022 | 12 | 5 | 17 |
| 2023 | 10 | 14 | 24 |
| 2024 | 9 | 4 | 13 |
Below are the most recent publications written about "Epoxide Hydrolases" by people in Profiles.
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Strategies for the Immobilization and Signal Amplification of a Double Nanobody Sandwich ELISA for Human Microsomal Epoxide Hydrolase. Anal Chem. 2024 Dec 10; 96(49):19605-19614.
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Metabolomics reveals soluble epoxide hydrolase as a therapeutic target for high-sucrose diet-mediated gut barrier dysfunction. Proc Natl Acad Sci U S A. 2024 Nov 26; 121(48):e2409841121.
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Salt-sensitive hypertension in GR mutant rats is associated with altered plasma polyunsaturated fatty acid levels and aortic vascular reactivity. Pflugers Arch. 2025 Jan; 477(1):37-53.
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Randomized, double-blind, phase 1a single-ascending dose and food effect studies assessing safety and pharmacokinetics of EC5026 in healthy volunteers. Clin Transl Sci. 2024 Sep; 17(9):e70033.
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Triazine herbicide prometryn alters epoxide hydrolase activity and increases cytochrome P450 metabolites in murine livers via lipidomic profiling. Sci Rep. 2024 08 19; 14(1):19135.
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Preclinical Evaluation of Soluble Epoxide Hydrolase Inhibitor AMHDU against Neuropathic Pain. Int J Mol Sci. 2024 Aug 14; 25(16).
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Cytochrome P450-soluble epoxide hydrolase oxylipins, depression and cognition in type 2 diabetes. J Diabetes Complications. 2024 Sep; 38(9):108826.
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Design and Synthesis of sEH/HDAC6 Dual-Targeting Inhibitors for the Treatment of Inflammatory Pain. J Med Chem. 2024 Aug 08; 67(15):12887-12911.
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Effects of sEH inhibition on the eicosanoid and cytokine storms in SARS-CoV-2-infected mice. FASEB J. 2024 May 31; 38(10):e23692.
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Enhancing cancer immunotherapy via inhibition of soluble epoxide hydrolase. Proc Natl Acad Sci U S A. 2024 Feb 13; 121(7):e2314085121.