Cyclic AMP-Dependent Protein Kinase RIalpha Subunit
"Cyclic AMP-Dependent Protein Kinase RIalpha Subunit" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A type I cAMP-dependent protein kinase regulatory subunit that plays a role in confering CYCLIC AMP activation of protein kinase activity. It has a lower affinity for cAMP than the CYCLIC-AMP-DEPENDENT PROTEIN KINASE RIBETA SUBUNIT.
| Descriptor ID |
D054756
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.150.125.750.625 D12.644.360.200.125.750.625 D12.776.476.200.125.750.124
|
| Concept/Terms |
Cyclic AMP-Dependent Protein Kinase RIalpha Subunit- Cyclic AMP-Dependent Protein Kinase RIalpha Subunit
- Cyclic AMP Dependent Protein Kinase RIalpha Subunit
- RIalpha, cAMP Protein Kinase
- Regulatory Subunit RIalpha, Cyclic-AMP-Dependent Protein Kinase
- Regulatory Subunit RIalpha, Cyclic AMP Dependent Protein Kinase
- Protein Kinase A, RIalpha Subunit
- RIalpha, PKA
- PKA RIalpha
- Cyclic-AMP-Dependent Protein Kinase RIalpha Subunit
- RI alpha, cAMP Protein Kinase
- RIalpha, Protein Kinase A
|
Below are MeSH descriptors whose meaning is more general than "Cyclic AMP-Dependent Protein Kinase RIalpha Subunit".
Below are MeSH descriptors whose meaning is more specific than "Cyclic AMP-Dependent Protein Kinase RIalpha Subunit".
This graph shows the total number of publications written about "Cyclic AMP-Dependent Protein Kinase RIalpha Subunit" by people in this website by year, and whether "Cyclic AMP-Dependent Protein Kinase RIalpha Subunit" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 6 | 6 |
| 2005 | 0 | 4 | 4 |
| 2006 | 0 | 2 | 2 |
| 2007 | 1 | 4 | 5 |
| 2008 | 1 | 1 | 2 |
| 2009 | 2 | 0 | 2 |
| 2010 | 2 | 2 | 4 |
| 2011 | 1 | 2 | 3 |
| 2012 | 0 | 1 | 1 |
| 2013 | 3 | 1 | 4 |
| 2014 | 2 | 0 | 2 |
| 2015 | 2 | 0 | 2 |
| 2016 | 2 | 1 | 3 |
| 2017 | 3 | 0 | 3 |
| 2018 | 2 | 0 | 2 |
| 2019 | 3 | 0 | 3 |
| 2020 | 2 | 1 | 3 |
| 2021 | 2 | 2 | 4 |
| 2022 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
Below are the most recent publications written about "Cyclic AMP-Dependent Protein Kinase RIalpha Subunit" by people in Profiles.
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Molecular determinants and signaling effects of PKA RIα phase separation. Mol Cell. 2024 Apr 18; 84(8):1570-1584.e7.
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Superficial Angiomyxomas Frequently Demonstrate Loss of Protein Kinase A Regulatory Subunit 1 Alpha Expression: Immunohistochemical Analysis of 29 Cases and Cutaneous Myxoid Neoplasms With Histopathologic Overlap. Am J Surg Pathol. 2022 02 01; 46(2):226-232.
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The Tails of Protein Kinase A. Mol Pharmacol. 2022 04; 101(4):219-225.
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Characterizing protein kinase A (PKA) subunits as macromolecular regulators of PKA RIα liquid-liquid phase separation. J Chem Phys. 2021 Jun 14; 154(22):221101.
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Response To: Feasibility of a Tumor Progression Model in PRKAR1A-inactivated Melanomas. Am J Surg Pathol. 2021 06 01; 45(6):869-870.
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Noncanonical protein kinase A activation by oligomerization of regulatory subunits as revealed by inherited Carney complex mutations. Proc Natl Acad Sci U S A. 2021 05 25; 118(21).
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Structural analyses of the PKA RIIβ holoenzyme containing the oncogenic DnaJB1-PKAc fusion protein reveal protomer asymmetry and fusion-induced allosteric perturbations in fibrolamellar hepatocellular carcinoma. PLoS Biol. 2020 12; 18(12):e3001018.
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Phase Separation of a PKA Regulatory Subunit Controls cAMP Compartmentation and Oncogenic Signaling. Cell. 2020 09 17; 182(6):1531-1544.e15.
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Clinical, histopathologic, and molecular profiles of PRKAR1A-inactivated melanocytic neoplasms. J Am Acad Dermatol. 2021 Apr; 84(4):1069-1071.
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Genomic and Clinicopathologic Characteristics of PRKAR1A-inactivated Melanomas: Toward Genetic Distinctions of Animal-type Melanoma/Pigment Synthesizing Melanoma. Am J Surg Pathol. 2020 06; 44(6):805-816.