Methylenetetrahydrofolate Reductase (NADPH2)
"Methylenetetrahydrofolate Reductase (NADPH2)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A flavoprotein amine oxidoreductase that catalyzes the reversible conversion of 5-methyltetrahydrofolate to 5,10-methylenetetrahydrofolate. This enzyme was formerly classified as EC 1.1.1.171.
| Descriptor ID |
D042965
|
| MeSH Number(s) |
D08.811.682.662.290 D12.776.331.775
|
| Concept/Terms |
Methylenetetrahydrofolate Reductase (NADPH2)- Methylenetetrahydrofolate Reductase (NADPH2)
- Methylenetetrahydrofolate Reductase (NADPH)
- Methylene-THF Reductase (NADPH)
- Methylenetetrahydrofolate Reductase
- 5,10-Methylenetetrahydrofolate Reductase (NADPH)
- Methylene Tetrahydrofolate Reductase
- Tetrahydrofolate Reductase, Methylene
|
Below are MeSH descriptors whose meaning is more general than "Methylenetetrahydrofolate Reductase (NADPH2)".
Below are MeSH descriptors whose meaning is more specific than "Methylenetetrahydrofolate Reductase (NADPH2)".
This graph shows the total number of publications written about "Methylenetetrahydrofolate Reductase (NADPH2)" by people in this website by year, and whether "Methylenetetrahydrofolate Reductase (NADPH2)" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 3 | 3 |
| 2000 | 0 | 3 | 3 |
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 2 | 2 |
| 2003 | 1 | 2 | 3 |
| 2004 | 2 | 1 | 3 |
| 2005 | 3 | 0 | 3 |
| 2006 | 3 | 1 | 4 |
| 2007 | 8 | 5 | 13 |
| 2008 | 0 | 4 | 4 |
| 2009 | 2 | 1 | 3 |
| 2010 | 7 | 2 | 9 |
| 2011 | 5 | 2 | 7 |
| 2012 | 2 | 1 | 3 |
| 2013 | 1 | 3 | 4 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 3 | 4 |
| 2016 | 1 | 2 | 3 |
| 2017 | 2 | 2 | 4 |
| 2019 | 0 | 1 | 1 |
| 2020 | 1 | 1 | 2 |
| 2021 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
Below are the most recent publications written about "Methylenetetrahydrofolate Reductase (NADPH2)" by people in Profiles.
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Newborn Dried Blood Spot Folate in Relation to Maternal Self-reported Folic Acid Intake, Autism Spectrum Disorder, and Developmental Delay. Epidemiology. 2024 Jul 01; 35(4):527-541.
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Investigating the Association of MTHFR C677T Gene Polymorphism with Recurrent Spontaneous Abortion Among Azerbaijani Women from Northwest Iran. Genet Test Mol Biomarkers. 2023 Oct; 27(10):339-344.
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Associations between Genetic Variants and Blood Biomarkers of One-Carbon Metabolism in Postmenopausal Women from the Women's Health Initiative Observational Study. J Nutr. 2022 04 01; 152(4):1099-1106.
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Shifting landscapes of human MTHFR missense-variant effects. Am J Hum Genet. 2021 07 01; 108(7):1283-1300.
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Prenatal Multivitamin Use and MTHFR Genotype Are Associated with Newborn Cord Blood DNA Methylation. Int J Environ Res Public Health. 2020 12 09; 17(24).
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Genetic variants in the MTHFR are not associated with fatty liver disease. Liver Int. 2020 08; 40(8):1934-1940.
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Clinical evaluation of germline polymorphisms associated with capecitabine toxicity in breast cancer: TBCRC-015. Breast Cancer Res Treat. 2020 Jun; 181(3):623-633.
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MTHFR gene polymorphisms and susceptibility to rheumatoid arthritis: a meta-analysis based on 16 studies. Clin Rheumatol. 2020 Aug; 39(8):2267-2279.
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Meta-analysis of association of FTO genetic variation with PCOS must account for obesity. Genomics. 2020 05; 112(3):2164-2165.
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Partitioning of One-Carbon Units in Folate and Methionine Metabolism Is Essential for Neural Tube Closure. Cell Rep. 2017 Nov 14; 21(7):1795-1808.