"tau Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Microtubule-associated proteins that are mainly expressed in neurons. Tau proteins constitute several isoforms and play an important role in the assembly of tubulin monomers into microtubules and in maintaining the cytoskeleton and axonal transport. Aggregation of specific sets of tau proteins in filamentous inclusions is the common feature of intraneuronal and glial fibrillar lesions (NEUROFIBRILLARY TANGLES; NEUROPIL THREADS) in numerous neurodegenerative disorders (ALZHEIMER DISEASE; TAUOPATHIES).
| Descriptor ID |
D016875
|
| MeSH Number(s) |
D12.776.220.600.450.510 D12.776.631.560.510
|
| Concept/Terms |
tau Proteins- tau Proteins
- Proteins, tau
- tau Protein
- Protein, tau
|
Below are MeSH descriptors whose meaning is more general than "tau Proteins".
Below are MeSH descriptors whose meaning is more specific than "tau Proteins".
This graph shows the total number of publications written about "tau Proteins" by people in this website by year, and whether "tau Proteins" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 3 | 3 | 6 |
| 1996 | 2 | 4 | 6 |
| 1997 | 3 | 2 | 5 |
| 1998 | 8 | 6 | 14 |
| 1999 | 8 | 1 | 9 |
| 2000 | 2 | 2 | 4 |
| 2001 | 13 | 6 | 19 |
| 2002 | 7 | 3 | 10 |
| 2003 | 8 | 8 | 16 |
| 2004 | 11 | 4 | 15 |
| 2005 | 11 | 10 | 21 |
| 2006 | 14 | 18 | 32 |
| 2007 | 14 | 15 | 29 |
| 2008 | 16 | 17 | 33 |
| 2009 | 15 | 24 | 39 |
| 2010 | 29 | 30 | 59 |
| 2011 | 34 | 14 | 48 |
| 2012 | 31 | 28 | 59 |
| 2013 | 28 | 30 | 58 |
| 2014 | 26 | 24 | 50 |
| 2015 | 41 | 18 | 59 |
| 2016 | 42 | 19 | 61 |
| 2017 | 62 | 22 | 84 |
| 2018 | 50 | 31 | 81 |
| 2019 | 63 | 45 | 108 |
| 2020 | 48 | 40 | 88 |
| 2021 | 46 | 55 | 101 |
| 2022 | 17 | 88 | 105 |
| 2023 | 13 | 85 | 98 |
| 2024 | 70 | 48 | 118 |
| 2025 | 13 | 2 | 15 |
Below are the most recent publications written about "tau Proteins" by people in Profiles.
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18F-MK-6240 tau PET in patients at-risk for chronic traumatic encephalopathy. Mol Neurodegener. 2025 Feb 25; 20(1):23.
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Early Alzheimer's Disease with frequent neuritic plaques harbors neocortical tau seeds distinct from primary age-related tauopathy. Nat Commun. 2025 Feb 21; 16(1):1851.
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Retinal ganglion cell vulnerability to pathogenic tau in Alzheimer's disease. Acta Neuropathol Commun. 2025 Feb 15; 13(1):31.
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Phospho-tau serine-262 and serine-356 as biomarkers of pre-tangle soluble tau assemblies in Alzheimer's disease. Nat Med. 2025 Feb; 31(2):574-588.
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Searching for the cellular underpinnings of the selective vulnerability to tauopathic insults in Alzheimer's disease. Commun Biol. 2025 Feb 07; 8(1):195.
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Alzheimer Disease Blood Biomarkers and Cognition Among Individuals With Diabetes and Overweight or Obesity. JAMA Netw Open. 2025 Feb 03; 8(2):e2458149.
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Role of tau versus TDP-43 pathology on medial temporal lobe atrophy in aging and Alzheimer's disease. Alzheimers Dement. 2025 Feb; 21(2):e14582.
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Machine learning prediction of tau-PET in Alzheimer's disease using plasma, MRI, and clinical data. Alzheimers Dement. 2025 Feb; 21(2):e14600.
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Methods to crosswalk between cognitive test scores using data from the Alzheimer's Disease Neuroimaging Cohort. Alzheimers Dement. 2025 Feb; 21(2):e14597.
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Monoaminergic neurotransmitters are bimodal effectors of tau aggregation. Sci Adv. 2025 Jan 31; 11(5):eadr8055.