"Ochronosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The yellowish discoloration of connective tissue due to deposition of HOMOGENTISIC ACID (a brown-black pigment). This is due to defects in the metabolism of PHENYLALANINE and TYROSINE. Ochronosis occurs in ALKAPTONURIA, but has also been associated with exposure to certain chemicals (e.g., PHENOL, trinitrophenol, BENZENE DERIVATIVES).
| Descriptor ID |
D009794
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| MeSH Number(s) |
C23.550.744
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Ochronosis".
Below are MeSH descriptors whose meaning is more specific than "Ochronosis".
This graph shows the total number of publications written about "Ochronosis" by people in this website by year, and whether "Ochronosis" was a major or minor topic of these publications.
Below are the most recent publications written about "Ochronosis" by people in Profiles.
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Clinical Images: Ochronotic arthropathy. Arthritis Rheumatol. 2017 11; 69(11):2208.
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Ochronosis in a murine model of alkaptonuria is synonymous to that in the human condition. Osteoarthritis Cartilage. 2012 Aug; 20(8):880-6.
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Clinical images: synovial fluid clues to ochronosis. Arthritis Rheum. 2012 Feb; 64(2):473.
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Exogenous ochronosis. An update on clinical features, causative agents and treatment options. Am J Clin Dermatol. 2001; 2(4):213-7.
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Multiple familiar occurrence of ochronotic arthropathy. Orthopedics. 1998 May; 21(5):590-2.