"Lipoprotein Lipase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme of the hydrolase class that catalyzes the reaction of triacylglycerol and water to yield diacylglycerol and a fatty acid anion. The enzyme hydrolyzes triacylglycerols in chylomicrons, very-low-density lipoproteins, low-density lipoproteins, and diacylglycerols. It occurs on capillary endothelial surfaces, especially in mammary, muscle, and adipose tissue. Genetic deficiency of the enzyme causes familial hyperlipoproteinemia Type I. (Dorland, 27th ed) EC 3.1.1.34.
| Descriptor ID |
D008071
|
| MeSH Number(s) |
D08.811.277.352.100.430
|
| Concept/Terms |
Lipoprotein Lipase- Lipoprotein Lipase
- Lipase, Lipoprotein
- Diglyceride Lipase
- Lipase, Diglyceride
- Heparin-Clearing Factor
- Factor, Heparin-Clearing
- Heparin Clearing Factor
- Post-Heparin Lipase
- Lipase, Post-Heparin
- Post Heparin Lipase
- Postheparin Lipase
- Lipase, Postheparin
- Postheparin Lipoprotein Lipase
- Lipase, Postheparin Lipoprotein
- Lipoprotein Lipase, Postheparin
- Diacylglycerol Lipase
- Lipase, Diacylglycerol
- Lipemia-Clearing Factor
- Factor, Lipemia-Clearing
- Lipemia Clearing Factor
|
Below are MeSH descriptors whose meaning is more general than "Lipoprotein Lipase".
Below are MeSH descriptors whose meaning is more specific than "Lipoprotein Lipase".
This graph shows the total number of publications written about "Lipoprotein Lipase" by people in this website by year, and whether "Lipoprotein Lipase" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 5 | 2 | 7 |
| 1996 | 5 | 1 | 6 |
| 1997 | 4 | 1 | 5 |
| 1998 | 2 | 2 | 4 |
| 1999 | 3 | 1 | 4 |
| 2000 | 3 | 2 | 5 |
| 2001 | 3 | 1 | 4 |
| 2002 | 4 | 2 | 6 |
| 2003 | 5 | 4 | 9 |
| 2004 | 2 | 4 | 6 |
| 2005 | 3 | 1 | 4 |
| 2006 | 8 | 1 | 9 |
| 2007 | 4 | 4 | 8 |
| 2008 | 6 | 3 | 9 |
| 2009 | 3 | 7 | 10 |
| 2010 | 6 | 3 | 9 |
| 2011 | 7 | 5 | 12 |
| 2012 | 8 | 1 | 9 |
| 2013 | 0 | 2 | 2 |
| 2014 | 8 | 3 | 11 |
| 2015 | 5 | 1 | 6 |
| 2016 | 12 | 2 | 14 |
| 2017 | 6 | 0 | 6 |
| 2018 | 5 | 2 | 7 |
| 2019 | 4 | 1 | 5 |
| 2020 | 4 | 3 | 7 |
| 2021 | 2 | 1 | 3 |
| 2022 | 2 | 1 | 3 |
| 2023 | 3 | 2 | 5 |
| 2024 | 4 | 0 | 4 |
Below are the most recent publications written about "Lipoprotein Lipase" by people in Profiles.
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Distinct strategies for intravascular triglyceride metabolism in hearts of mammals and lower vertebrate species. JCI Insight. 2024 Sep 17; 9(20).
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APOA5 deficiency causes hypertriglyceridemia by reducing amounts of lipoprotein lipase in capillaries. J Lipid Res. 2024 07; 65(7):100578.
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Carboxyl-terminal sequences in APOA5 are important for suppressing ANGPTL3/8 activity. Proc Natl Acad Sci U S A. 2024 Apr 23; 121(17):e2322332121.
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Quantification of lipoprotein lipase in mouse plasma with a sandwich enzyme-linked immunosorbent assay. J Lipid Res. 2024 04; 65(4):100532.
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Hypertriglyceridemia in Apoa5-/- mice results from reduced amounts of lipoprotein lipase in the capillary lumen. J Clin Invest. 2023 12 01; 133(23).
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Imaging the ANGPTL3/8-mediated regulation of lipoprotein lipase in the heart. J Lipid Res. 2023 12; 64(12):100467.
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The lipoprotein lipase that is shuttled into capillaries by GPIHBP1 enters the glycocalyx where it mediates lipoprotein processing. Proc Natl Acad Sci U S A. 2023 Oct 31; 120(44):e2313825120.
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Inverse effects of APOC2 and ANGPTL4 on the conformational dynamics of lid-anchoring structures in lipoprotein lipase. Proc Natl Acad Sci U S A. 2023 05 02; 120(18):e2221888120.
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Intracapillary LPL levels in brown adipose tissue, visualized with an antibody-based approach, are regulated by ANGPTL4 at thermoneutral temperatures. Proc Natl Acad Sci U S A. 2023 02 21; 120(8):e2219833120.
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Modulation of Milk and Lipid Synthesis and Secretion in a3-Dimensional Mouse Mammary Epithelial Cell Culture Model: Effects of Palmitate and Orlistat. Nutrients. 2022 Nov 22; 14(23).