"Kininogens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Endogenous peptides present in most body fluids. Certain enzymes convert them to active KININS which are involved in inflammation, blood clotting, complement reactions, etc. Kininogens belong to the cystatin superfamily. They are cysteine proteinase inhibitors. HIGH-MOLECULAR-WEIGHT KININOGEN; (HMWK); is split by plasma kallikrein to produce BRADYKININ. LOW-MOLECULAR-WEIGHT KININOGEN; (LMWK); is split by tissue kallikrein to produce KALLIDIN.
| Descriptor ID |
D007704
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| MeSH Number(s) |
D12.644.276.812.654 D12.776.124.125.635 D12.776.467.812.654 D12.776.811.420 D23.119.630 D23.469.050.375.425 D23.529.812.654
|
| Concept/Terms |
Kininogens- Kininogens
- Prokinins
- Prekinins
- Cystatins, Kininogen
- Kininogen Cystatins
|
Below are MeSH descriptors whose meaning is more general than "Kininogens".
Below are MeSH descriptors whose meaning is more specific than "Kininogens".
This graph shows the total number of publications written about "Kininogens" by people in this website by year, and whether "Kininogens" was a major or minor topic of these publications.
Below are the most recent publications written about "Kininogens" by people in Profiles.
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A genetic association study of circulating coagulation factor VIII and von Willebrand factor levels. Blood. 2024 05 02; 143(18):1845-1855.
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A High-Content Screen Identifies Drugs That Restrict Tumor Cell Extravasation across the Endothelial Barrier. Cancer Res. 2021 02 01; 81(3):619-633.
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Changes in the Glycosylation of Kininogen and the Development of a Kininogen-Based Algorithm for the Early Detection of HCC. Cancer Epidemiol Biomarkers Prev. 2017 05; 26(5):795-803.
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Peptidomic Identification of Serum Peptides Diagnosing Preeclampsia. PLoS One. 2013; 8(6):e65571.
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Substrate specificity studies of the cysteine peptidases falcipain-2 and falcipain-3 from Plasmodium falciparum and demonstration of their kininogenase activity. Mol Biochem Parasitol. 2013 Feb; 187(2):111-6.
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Intracellular proteolysis of kininogen by malaria parasites promotes release of active kinins. Malar J. 2012 May 07; 11:156.
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Detection and diagnostic applicability of human urinary kininogen in kala-azar patients. Parasitol Res. 2012 Oct; 111(4):1851-5.
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Different effect of hydrogelation on antifouling and circulation properties of dextran-iron oxide nanoparticles. Mol Pharm. 2012 Mar 05; 9(3):539-45.
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Coagulation, fibrinolytic and inhibitory proteins in acute myocardial infarction and angina pectoris. Am J Med. 1994 Jun; 96(6):571.
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Blood coagulation, fibrinolytic, and inhibitory proteins in end-stage renal disease: effect of hemodialysis. Am J Kidney Dis. 1994 Jun; 23(6):828-35.