"Cantharidin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A toxic compound, isolated from the Spanish fly or blistering beetle (Lytta (Cantharis) vesicatoria) and other insects. It is a potent and specific inhibitor of protein phosphatases 1 (PP1) and 2A (PP2A). This compound can produce severe skin inflammation, and is extremely toxic if ingested orally.
| Descriptor ID |
D002193
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| MeSH Number(s) |
D03.633.100.127.125
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cantharidin".
Below are MeSH descriptors whose meaning is more specific than "Cantharidin".
This graph shows the total number of publications written about "Cantharidin" by people in this website by year, and whether "Cantharidin" was a major or minor topic of these publications.
Below are the most recent publications written about "Cantharidin" by people in Profiles.
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Therapeutic Approaches and Special Considerations for Treating Molluscum Contagiosum. J Drugs Dermatol. 2021 Nov 01; 20(11):1185-1190.
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Pooled Results of Two Randomized Phase III Trials Evaluating VP-102, a Drug-Device Combination Product Containing Cantharidin 0.7% (w/v) for the Treatment of Molluscum Contagiosum. Am J Clin Dermatol. 2021 Mar; 22(2):257-265.
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Safety and Efficacy of VP-102, a Proprietary, Drug-Device Combination Product Containing Cantharidin, 0.7% (w/v), in Children and Adults With Molluscum Contagiosum: Two Phase 3 Randomized Clinical Trials. JAMA Dermatol. 2020 12 01; 156(12):1315-1323.
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The Crg1 N-Terminus Is Essential for Methyltransferase Activity and Cantharidin Resistance in Saccharomyces cerevisiae. Biochemistry. 2019 04 02; 58(13):1799-1809.
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The natural anticancer agent cantharidin alters GPI-anchored protein sorting by targeting Cdc1-mediated remodeling in endoplasmic reticulum. J Biol Chem. 2019 03 15; 294(11):3837-3852.
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Safety and efficacy of topical cantharidin for the treatment of pediatric molluscum contagiosum: a prospective, randomized, double-blind, placebo-controlled pilot trial. Int J Dermatol. 2018 Aug; 57(8):1001-1006.
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Cantharidin is Superior to Trichloroacetic Acid for the Treatment of Non-mucosal Genital Warts: A Pilot Randomized Controlled Trial. Clin Exp Obstet Gynecol. 2018; 45(3):383-386.
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The utility of cantharidin for the treatment of molluscum contagiosum. Pediatr Dermatol. 2015 Mar-Apr; 32(2):295.
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Cantharidins induce ER stress and a terminal unfolded protein response in OSCC. J Dent Res. 2015 Feb; 94(2):320-9.
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A novel small molecule methyltransferase is important for virulence in Candida albicans. ACS Chem Biol. 2013 Dec 20; 8(12):2785-93.