"Proton Pump Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds that inhibit H(+)-K(+)-EXCHANGING ATPASE. They are used as ANTI-ULCER AGENTS and sometimes in place of HISTAMINE H2 ANTAGONISTS for GASTROESOPHAGEAL REFLUX.
| Descriptor ID |
D054328
|
| MeSH Number(s) |
D27.505.519.389.848
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Proton Pump Inhibitors".
Below are MeSH descriptors whose meaning is more specific than "Proton Pump Inhibitors".
This graph shows the total number of publications written about "Proton Pump Inhibitors" by people in this website by year, and whether "Proton Pump Inhibitors" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 2 | 0 | 2 |
| 1999 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 1 | 3 | 4 |
| 2003 | 2 | 2 | 4 |
| 2004 | 3 | 3 | 6 |
| 2005 | 4 | 3 | 7 |
| 2006 | 4 | 4 | 8 |
| 2007 | 4 | 3 | 7 |
| 2008 | 6 | 4 | 10 |
| 2009 | 5 | 2 | 7 |
| 2010 | 3 | 3 | 6 |
| 2011 | 5 | 1 | 6 |
| 2012 | 5 | 6 | 11 |
| 2013 | 9 | 9 | 18 |
| 2014 | 6 | 3 | 9 |
| 2015 | 6 | 6 | 12 |
| 2016 | 12 | 5 | 17 |
| 2017 | 15 | 6 | 21 |
| 2018 | 10 | 4 | 14 |
| 2019 | 10 | 4 | 14 |
| 2020 | 12 | 12 | 24 |
| 2021 | 5 | 13 | 18 |
| 2022 | 7 | 11 | 18 |
| 2023 | 3 | 10 | 13 |
| 2024 | 10 | 6 | 16 |
| 2025 | 3 | 0 | 3 |
Below are the most recent publications written about "Proton Pump Inhibitors" by people in Profiles.
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The effectiveness and risks of Treating people with Idiopathic Pulmonary fibrosis with the Addition of Lansoprazole (TIPAL): study protocol for a randomised placebo-controlled multicentre clinical trial. BMJ Open. 2025 Feb 05; 15(2):e088604.
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Comparing the efficacy of different proton pump inhibitor dosing regimens for the treatment of gastroesophageal reflux disease: a systematic review and meta-analysis. Dis Esophagus. 2025 Jan 07; 38(1).
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ACG Clinical Guideline: Diagnosis and Management of Eosinophilic Esophagitis. Am J Gastroenterol. 2025 Jan 01; 120(1):31-59.
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Proton Pump Inhibitor Use and Incident Cardiovascular Disease in Older Postmenopausal Women. J Am Geriatr Soc. 2025 Feb; 73(2):411-421.
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Management of Patients With Refractory Reflux-Like Symptoms Despite Proton Pump Inhibitor Therapy: Evidence-Based Consensus Statements. Aliment Pharmacol Ther. 2025 Feb; 61(4):636-650.
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Hepatotoxicity Score: A New Method to Adjust for Use of Potentially Hepatotoxic Medications by Chronic Liver Disease Status. Pharmacoepidemiol Drug Saf. 2024 12; 33(12):e70069.
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Cost-Effectiveness Analysis of Current Treatment Options for Eosinophilic Esophagitis. Am J Gastroenterol. 2025 Jan 01; 120(1):161-172.
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The Cost Effectiveness of Adjunctive Treatments for Proton Pump Inhibitor-Refractory Gastroesophageal Reflux Disease. Clin Drug Investig. 2024 Sep; 44(9):703-714.
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ACG Clinical Guideline: Treatment of Helicobacter pylori Infection. Am J Gastroenterol. 2024 Sep 01; 119(9):1730-1753.
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Analysis of immune checkpoint inhibitors for advanced non-small cell lung cancer in patients receiving antacids. Respir Investig. 2024 Nov; 62(6):951-959.