Retinoblastoma-Like Protein p130
"Retinoblastoma-Like Protein p130" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A negative regulator of the CELL CYCLE that undergoes PHOSPHORYLATION by CYCLIN-DEPENDENT KINASES. RBL2 contains a conserved pocket region that binds E2F4 TRANSCRIPTION FACTOR and E2F5 TRANSCRIPTION FACTOR. RBL2 also interacts with viral ONCOPROTEINS such as POLYOMAVIRUS TUMOR ANTIGENS; ADENOVIRUS E1A PROTEINS; and PAPILLOMAVIRUS E7 PROTEINS.
| Descriptor ID |
D050717
|
| MeSH Number(s) |
D12.776.624.776.735 D12.776.660.794 D12.776.744.755
|
| Concept/Terms |
Retinoblastoma-Like Protein p130- Retinoblastoma-Like Protein p130
- p130, Retinoblastoma-Like Protein
- Retinoblastoma Like Protein p130
- Retinoblastoma-Like Protein 2
- Retinoblastoma Like Protein 2
- RBL2 Protein
|
Below are MeSH descriptors whose meaning is more general than "Retinoblastoma-Like Protein p130".
Below are MeSH descriptors whose meaning is more specific than "Retinoblastoma-Like Protein p130".
This graph shows the total number of publications written about "Retinoblastoma-Like Protein p130" by people in this website by year, and whether "Retinoblastoma-Like Protein p130" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 3 | 3 |
| 1997 | 0 | 2 | 2 |
| 1998 | 0 | 4 | 4 |
| 1999 | 0 | 4 | 4 |
| 2000 | 0 | 7 | 7 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 5 | 5 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 3 | 3 |
| 2005 | 1 | 3 | 4 |
| 2006 | 0 | 1 | 1 |
| 2007 | 2 | 0 | 2 |
| 2008 | 1 | 0 | 1 |
| 2009 | 2 | 0 | 2 |
| 2010 | 2 | 1 | 3 |
| 2011 | 1 | 2 | 3 |
| 2014 | 1 | 1 | 2 |
| 2024 | 0 | 1 | 1 |
Below are the most recent publications written about "Retinoblastoma-Like Protein p130" by people in Profiles.
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RBL2 represses the transcriptional activity of Multicilin to inhibit multiciliogenesis. Cell Death Dis. 2024 01 22; 15(1):81.
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Rb family proteins enforce the homeostasis of quiescent hematopoietic stem cells by repressing Socs3 expression. J Exp Med. 2017 Jul 03; 214(7):1901-1912.
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Structural mechanisms of DREAM complex assembly and regulation. Genes Dev. 2015 May 01; 29(9):961-74.
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Rb suppresses human cone-precursor-derived retinoblastoma tumours. Nature. 2014 Oct 16; 514(7522):385-8.
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Organ size control is dominant over Rb family inactivation to restrict proliferation in vivo. Cell Rep. 2014 Jul 24; 8(2):371-81.
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The specific role of pRb in p16 (INK4A) -mediated arrest of normal and malignant human breast cells. Cell Cycle. 2012 Mar 01; 11(5):1008-13.
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MicroRNA profiling predicts a variance in the proliferative potential of cardiac progenitor cells derived from neonatal and adult murine hearts. J Mol Cell Cardiol. 2012 Jan; 52(1):264-72.
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Rb and p130 control cell cycle gene silencing to maintain the postmitotic phenotype in cardiac myocytes. J Cell Biol. 2011 Aug 08; 194(3):407-23.
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Critical role of the Rb family in myoblast survival and fusion. PLoS One. 2011 Mar 10; 6(3):e17682.
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G1 arrest and differentiation can occur independently of Rb family function. J Cell Biol. 2010 Nov 15; 191(4):809-25.