X Chromosome Inactivation
"X Chromosome Inactivation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A dosage compensation process occurring at an early embryonic stage in mammalian development whereby, at random, one X CHROMOSOME of the pair is repressed in the somatic cells of females.
| Descriptor ID |
D049951
|
| MeSH Number(s) |
G05.308.203.249.970
|
| Concept/Terms |
X Chromosome Inactivation- X Chromosome Inactivation
- Chromosome Inactivation, X
- Inactivation, X Chromosome
- Lyonization
- X-Inactivation
- X Inactivation
- Inactivation, X
- X Inactivations
|
Below are MeSH descriptors whose meaning is more general than "X Chromosome Inactivation".
Below are MeSH descriptors whose meaning is more specific than "X Chromosome Inactivation".
This graph shows the total number of publications written about "X Chromosome Inactivation" by people in this website by year, and whether "X Chromosome Inactivation" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 4 | 0 | 4 |
| 2006 | 8 | 1 | 9 |
| 2007 | 2 | 3 | 5 |
| 2008 | 6 | 2 | 8 |
| 2009 | 1 | 5 | 6 |
| 2010 | 3 | 4 | 7 |
| 2011 | 4 | 2 | 6 |
| 2012 | 3 | 3 | 6 |
| 2013 | 5 | 5 | 10 |
| 2014 | 2 | 2 | 4 |
| 2015 | 5 | 4 | 9 |
| 2016 | 10 | 2 | 12 |
| 2017 | 4 | 4 | 8 |
| 2018 | 5 | 4 | 9 |
| 2019 | 2 | 3 | 5 |
| 2020 | 3 | 3 | 6 |
| 2021 | 2 | 2 | 4 |
| 2022 | 1 | 1 | 2 |
| 2023 | 1 | 1 | 2 |
| 2024 | 2 | 3 | 5 |
Below are the most recent publications written about "X Chromosome Inactivation" by people in Profiles.
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A de novo int22h-1/int22h-2-flanked Xq28 deletion-associated preferential X-inactivation in a female with severe hemophilia B. Pediatr Blood Cancer. 2024 Dec; 71(12):e31332.
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A critical role for X-chromosome architecture in mammalian X-chromosome dosage compensation. Curr Opin Genet Dev. 2024 Aug; 87:102235.
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Cell-type-specific effects of age and sex on human cortical neurons. Neuron. 2024 Aug 07; 112(15):2524-2539.e5.
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Distributed X chromosome inactivation in brain circuitry is associated with X-linked disease penetrance of behavior. Cell Rep. 2024 04 23; 43(4):114068.
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Dissection of protein and RNA regions required for SPEN binding to XIST A-repeat RNA. RNA. 2024 02 16; 30(3):240-255.
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Impaired dynamic X-chromosome inactivation maintenance in T cells is a feature of spontaneous murine SLE that is exacerbated in female-biased models. J Autoimmun. 2023 09; 139:103084.
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Potato Virus X Inactivation and Characterization. Methods Mol Biol. 2023; 2671:257-271.
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A lifelong duty: how Xist maintains the inactive X chromosome. Curr Opin Genet Dev. 2022 08; 75:101927.
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Genes That Escape X Chromosome Inactivation Modulate Sex Differences in Valve Myofibroblasts. Circulation. 2022 02 15; 145(7):513-530.
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Xist nucleates local protein gradients to propagate silencing across the X chromosome. Cell. 2021 12 09; 184(25):6174-6192.e32.