"MicroRNAs" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Small double-stranded, non-protein coding RNAs, 21-25 nucleotides in length generated from single-stranded microRNA gene transcripts by the same RIBONUCLEASE III, Dicer, that produces small interfering RNAs (RNA, SMALL INTERFERING). They become part of the RNA-INDUCED SILENCING COMPLEX and repress the translation (TRANSLATION, GENETIC) of target RNA by binding to homologous 3'UTR region as an imperfect match. The small temporal RNAs (stRNAs), let-7 and lin-4, from C. elegans, are the first 2 miRNAs discovered, and are from a class of miRNAs involved in developmental timing.
| Descriptor ID |
D035683
|
| MeSH Number(s) |
D13.150.650.319 D13.444.735.150.319 D13.444.735.790.552.500
|
| Concept/Terms |
MicroRNAs- MicroRNAs
- MicroRNA
- miRNAs
- Micro RNA
- RNA, Micro
- miRNA
Primary MicroRNA- Primary MicroRNA
- MicroRNA, Primary
- Primary miRNA
- miRNA, Primary
- pri-miRNA
- pri miRNA
|
Below are MeSH descriptors whose meaning is more general than "MicroRNAs".
Below are MeSH descriptors whose meaning is more specific than "MicroRNAs".
This graph shows the total number of publications written about "MicroRNAs" by people in this website by year, and whether "MicroRNAs" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 1 | 2 |
| 2003 | 1 | 1 | 2 |
| 2004 | 3 | 1 | 4 |
| 2005 | 15 | 7 | 22 |
| 2006 | 12 | 8 | 20 |
| 2007 | 30 | 10 | 40 |
| 2008 | 55 | 20 | 75 |
| 2009 | 88 | 13 | 101 |
| 2010 | 116 | 19 | 135 |
| 2011 | 126 | 29 | 155 |
| 2012 | 126 | 33 | 159 |
| 2013 | 155 | 39 | 194 |
| 2014 | 159 | 38 | 197 |
| 2015 | 165 | 41 | 206 |
| 2016 | 116 | 39 | 155 |
| 2017 | 112 | 37 | 149 |
| 2018 | 117 | 32 | 149 |
| 2019 | 103 | 34 | 137 |
| 2020 | 105 | 34 | 139 |
| 2021 | 86 | 16 | 102 |
| 2022 | 86 | 4 | 90 |
| 2023 | 81 | 1 | 82 |
| 2024 | 49 | 13 | 62 |
| 2025 | 4 | 1 | 5 |
Below are the most recent publications written about "MicroRNAs" by people in Profiles.
-
The mutational landscape and functional effects of noncoding ultraconserved elements in human cancers. Sci Adv. 2025 Feb 21; 11(8):eado2830.
-
Peripheral blood miRNAs are associated with airflow below threshold in children with asthma. Respir Res. 2025 Jan 24; 26(1):38.
-
Rapid and quantitative functional interrogation of human enhancer variant activity in live mice. Nat Commun. 2025 Jan 06; 16(1):409.
-
Selective diagnostics of Amyotrophic Lateral Sclerosis, Alzheimer's and Parkinson's Diseases with machine learning and miRNA. Metab Brain Dis. 2025 Jan 02; 40(1):79.
-
Supramolecular DNA Nanodevice Assembled via RCA and HCR Cascade Reaction on Tetrahedral DNA Nanostructure for Sensitive Detection and Intracellular Imaging of Dual-miRNAs Associated with Liver Cancer. Anal Chem. 2025 Jan 14; 97(1):686-693.
-
miRNAome-metabolome wide association study reveals effects of miRNA regulation in eosinophilia and airflow obstruction in childhood asthma. EBioMedicine. 2025 Feb; 112:105534.
-
Bioengineered miR-7-5p modulates non-small cell lung cancer cell metabolism to improve therapy. Mol Pharmacol. 2025 Jan; 107(1):100006.
-
MicroRNA in pediatric pulmonary hypertension microRNA profiling to inform disease classification, severity, and treatment response in pediatric pulmonary hypertension. Am J Physiol Heart Circ Physiol. 2025 Jan 01; 328(1):H47-H57.
-
Frontiers in pancreatic cancer on biomarkers, microenvironment, and immunotherapy. Cancer Lett. 2025 Feb 01; 610:217350.
-
Associations between human milk EV-miRNAs and oligosaccharide concentrations in human milk. Front Immunol. 2024; 15:1463463.