Receptors, Adrenergic, beta-2
"Receptors, Adrenergic, beta-2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of beta-adrenergic receptors (RECEPTORS, ADRENERGIC, BETA). The adrenergic beta-2 receptors are more sensitive to EPINEPHRINE than to NOREPINEPHRINE and have a high affinity for the agonist TERBUTALINE. They are widespread, with clinically important roles in SKELETAL MUSCLE; LIVER; and vascular, bronchial, gastrointestinal, and genitourinary SMOOTH MUSCLE.
| Descriptor ID |
D018343
|
| MeSH Number(s) |
D12.776.543.750.670.300.300.340.200 D12.776.543.750.695.150.300.340.725 D12.776.543.750.720.330.300.340.200
|
| Concept/Terms |
Receptors, Adrenergic, beta-2- Receptors, Adrenergic, beta-2
- beta 2 Adrenergic Receptors
- Receptor, Adrenergic, beta-2
- Receptors, beta-2 Adrenergic
- Receptors, beta 2 Adrenergic
- Adrenergic beta-2 Receptors
- Adrenergic beta 2 Receptors
- Receptors, Adrenergic beta-2
- beta-2 Receptors, Adrenergic
- Adrenergic Receptor, beta-2
- Adrenergic Receptor, beta 2
- Receptor, beta-2 Adrenergic
- beta-2 Adrenergic Receptor
- beta-2 Adrenergic Receptors
- Adrenergic Receptors, beta-2
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Adrenergic, beta-2".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Biogenic Amine [D12.776.543.750.670]
- Receptors, Catecholamine [D12.776.543.750.670.300]
- Receptors, Adrenergic [D12.776.543.750.670.300.300]
- Receptors, Adrenergic, beta [D12.776.543.750.670.300.300.340]
- Receptors, Adrenergic, beta-2 [D12.776.543.750.670.300.300.340.200]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Catecholamine [D12.776.543.750.695.150]
- Receptors, Adrenergic [D12.776.543.750.695.150.300]
- Receptors, Adrenergic, beta [D12.776.543.750.695.150.300.340]
- Receptors, Adrenergic, beta-2 [D12.776.543.750.695.150.300.340.725]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Catecholamine [D12.776.543.750.720.330]
- Receptors, Adrenergic [D12.776.543.750.720.330.300]
- Receptors, Adrenergic, beta [D12.776.543.750.720.330.300.340]
- Receptors, Adrenergic, beta-2 [D12.776.543.750.720.330.300.340.200]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Adrenergic, beta-2".
This graph shows the total number of publications written about "Receptors, Adrenergic, beta-2" by people in this website by year, and whether "Receptors, Adrenergic, beta-2" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 1 | 2 |
| 1996 | 1 | 1 | 2 |
| 1997 | 2 | 0 | 2 |
| 1998 | 1 | 2 | 3 |
| 1999 | 2 | 0 | 2 |
| 2000 | 2 | 0 | 2 |
| 2001 | 7 | 3 | 10 |
| 2002 | 7 | 4 | 11 |
| 2003 | 6 | 4 | 10 |
| 2004 | 6 | 2 | 8 |
| 2005 | 6 | 4 | 10 |
| 2006 | 6 | 2 | 8 |
| 2007 | 10 | 6 | 16 |
| 2008 | 9 | 2 | 11 |
| 2009 | 13 | 2 | 15 |
| 2010 | 7 | 3 | 10 |
| 2011 | 12 | 4 | 16 |
| 2012 | 8 | 5 | 13 |
| 2013 | 11 | 5 | 16 |
| 2014 | 12 | 2 | 14 |
| 2015 | 7 | 7 | 14 |
| 2016 | 11 | 5 | 16 |
| 2017 | 6 | 2 | 8 |
| 2018 | 8 | 2 | 10 |
| 2019 | 6 | 1 | 7 |
| 2020 | 3 | 4 | 7 |
| 2021 | 4 | 2 | 6 |
| 2022 | 1 | 0 | 1 |
| 2023 | 3 | 0 | 3 |
Below are the most recent publications written about "Receptors, Adrenergic, beta-2" by people in Profiles.
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Gαs is dispensable for β-arrestin coupling but dictates GRK selectivity and is predominant for gene expression regulation by β2-adrenergic receptor. J Biol Chem. 2023 11; 299(11):105293.
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Constrained catecholamines gain β2AR selectivity through allosteric effects on pocket dynamics. Nat Commun. 2023 04 14; 14(1):2138.
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Passing the βAR: PI3Kγ Is the Judge of β Adrenergic Receptor Resensitization. Circ Res. 2023 03 17; 132(6):704-706.
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Elucidation of a dynamic interplay between a beta-2 adrenergic receptor, its agonist, and stimulatory G protein. Proc Natl Acad Sci U S A. 2023 03 07; 120(10):e2215916120.
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Non-canonical β-adrenergic activation of ERK at endosomes. Nature. 2022 11; 611(7934):173-179.
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ADRB2 haplotypes and asthma exacerbations in children and young adults: An individual participant data meta-analysis. Clin Exp Allergy. 2021 09; 51(9):1157-1171.
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Defining a Role for G-Protein Coupled Receptor/cAMP/CRE-Binding Protein Signaling in Hair Follicle Stem Cell Activation. J Invest Dermatol. 2022 01; 142(1):53-64.e3.
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Exploring the Activation Process of the β2AR-Gs Complex. J Am Chem Soc. 2021 07 28; 143(29):11044-11051.
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Ligand-specific pharmacogenetic effects of nonsynonymous mutations. Pharmacogenet Genomics. 2021 06 01; 31(4):75-82.
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Skin-Resident β2AR Signaling Delays Burn Wound Healing. J Invest Dermatol. 2021 08; 141(8):2098-2101.e4.