"Cellular Senescence" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Process by which cells irreversibly stop dividing and enter a state of permanent growth arrest without undergoing CELL DEATH. Senescence can be induced by DNA DAMAGE or other cellular stresses, such as OXIDATIVE STRESS.
| Descriptor ID |
D016922
|
| MeSH Number(s) |
G04.043
|
| Concept/Terms |
Cell Aging- Cell Aging
- Cellular Ageing
- Ageing, Cellular
- Aging, Cell
- Senescence, Replicative
- Cellular Aging
- Aging, Cellular
- Replicative Senescence
- Cell Ageing
- Ageing, Cell
Senescence-Associated Secretory Phenotype- Senescence-Associated Secretory Phenotype
- Phenotype, Senescence-Associated Secretory
- Secretory Phenotype, Senescence-Associated
- Senescence Associated Secretory Phenotype
|
Below are MeSH descriptors whose meaning is more general than "Cellular Senescence".
Below are MeSH descriptors whose meaning is more specific than "Cellular Senescence".
This graph shows the total number of publications written about "Cellular Senescence" by people in this website by year, and whether "Cellular Senescence" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 2 | 2 |
| 1996 | 2 | 7 | 9 |
| 1997 | 0 | 4 | 4 |
| 1998 | 2 | 7 | 9 |
| 1999 | 5 | 6 | 11 |
| 2000 | 5 | 5 | 10 |
| 2001 | 4 | 8 | 12 |
| 2002 | 5 | 3 | 8 |
| 2003 | 6 | 14 | 20 |
| 2004 | 5 | 4 | 9 |
| 2005 | 5 | 10 | 15 |
| 2006 | 7 | 5 | 12 |
| 2007 | 13 | 6 | 19 |
| 2008 | 15 | 12 | 27 |
| 2009 | 14 | 8 | 22 |
| 2010 | 15 | 12 | 27 |
| 2011 | 23 | 13 | 36 |
| 2012 | 18 | 21 | 39 |
| 2013 | 18 | 25 | 43 |
| 2014 | 21 | 22 | 43 |
| 2015 | 19 | 19 | 38 |
| 2016 | 12 | 14 | 26 |
| 2017 | 23 | 9 | 32 |
| 2018 | 22 | 14 | 36 |
| 2019 | 33 | 14 | 47 |
| 2020 | 25 | 18 | 43 |
| 2021 | 22 | 16 | 38 |
| 2022 | 5 | 17 | 22 |
| 2023 | 10 | 17 | 27 |
| 2024 | 18 | 16 | 34 |
| 2025 | 4 | 1 | 5 |
Below are the most recent publications written about "Cellular Senescence" by people in Profiles.
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CircFUNDC1 interacts with CDK9 to promote mitophagy in nucleus pulposus cells under oxidative stress and ameliorates intervertebral disc degeneration. Cell Death Dis. 2025 Feb 13; 16(1):94.
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Cellular senescence induced by cholesterol accumulation is mediated by lysosomal ABCA1 in APOE4 and AD. Mol Neurodegener. 2025 Feb 04; 20(1):15.
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Transcriptomic markers of biological aging in breast cancer survivors: a longitudinal study. J Natl Cancer Inst. 2025 Feb 01; 117(2):312-321.
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Senescence-related genes are associated with the immunopathology signature of American tegumentary leishmaniasis lesions and may predict progression to mucosal leishmaniasis. Clin Exp Immunol. 2025 Jan 21; 219(1).
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FBP1 controls liver cancer evolution from senescent MASH hepatocytes. Nature. 2025 Jan; 637(8045):461-469.
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The Critical Role of Autophagy and Phagocytosis in the Aging Brain. Int J Mol Sci. 2024 Dec 25; 26(1).
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Development of Calcium-Dependent Phospholipase A2 Inhibitors to Target Cellular Senescence and Oxidative Stress in Neurodegenerative Diseases. Antioxid Redox Signal. 2024 Dec; 41(16-18):1100-1116.
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Senescent cell depletion alleviates obesity-related metabolic and cardiac disorders. Mol Metab. 2025 Jan; 91:102065.
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Telomere length and chronotype among women in the California Teachers Study (CTS). Chronobiol Int. 2024 Nov; 41(11):1480-1491.
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Arginine metabolism is a biomarker of red blood cell and human aging. Aging Cell. 2025 Feb; 24(2):e14388.