Lymphocytes, Tumor-Infiltrating
"Lymphocytes, Tumor-Infiltrating" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Lymphocytes that show specificity for autologous tumor cells. Ex vivo isolation and culturing of TIL with interleukin-2, followed by reinfusion into the patient, is one form of adoptive immunotherapy of cancer.
| Descriptor ID |
D016246
|
| MeSH Number(s) |
A11.118.637.555.567.650 A15.145.229.637.555.567.650 A15.382.490.555.567.650
|
| Concept/Terms |
Lymphocytes, Tumor-Infiltrating- Lymphocytes, Tumor-Infiltrating
- Lymphocytes, Tumor Infiltrating
- Tumor-Infiltrating Lymphocytes
- Lymphocyte, Tumor-Infiltrating
- Tumor Infiltrating Lymphocytes
- Tumor-Infiltrating Lymphocyte
Tumor-Derived Activated Cells- Tumor-Derived Activated Cells
- Activated Cell, Tumor-Derived
- Activated Cells, Tumor-Derived
- Tumor Derived Activated Cells
- Tumor-Derived Activated Cell
|
Below are MeSH descriptors whose meaning is more general than "Lymphocytes, Tumor-Infiltrating".
Below are MeSH descriptors whose meaning is more specific than "Lymphocytes, Tumor-Infiltrating".
This graph shows the total number of publications written about "Lymphocytes, Tumor-Infiltrating" by people in this website by year, and whether "Lymphocytes, Tumor-Infiltrating" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 2 | 2 | 4 |
| 1996 | 5 | 1 | 6 |
| 1998 | 0 | 5 | 5 |
| 1999 | 2 | 2 | 4 |
| 2000 | 2 | 2 | 4 |
| 2001 | 1 | 2 | 3 |
| 2002 | 0 | 3 | 3 |
| 2003 | 1 | 5 | 6 |
| 2004 | 1 | 3 | 4 |
| 2005 | 1 | 2 | 3 |
| 2006 | 1 | 4 | 5 |
| 2007 | 4 | 2 | 6 |
| 2008 | 2 | 4 | 6 |
| 2009 | 2 | 5 | 7 |
| 2010 | 3 | 3 | 6 |
| 2011 | 5 | 5 | 10 |
| 2012 | 1 | 4 | 5 |
| 2013 | 3 | 5 | 8 |
| 2014 | 7 | 9 | 16 |
| 2015 | 8 | 14 | 22 |
| 2016 | 16 | 14 | 30 |
| 2017 | 11 | 12 | 23 |
| 2018 | 11 | 15 | 26 |
| 2019 | 11 | 21 | 32 |
| 2020 | 12 | 20 | 32 |
| 2021 | 18 | 24 | 42 |
| 2022 | 4 | 9 | 13 |
| 2023 | 1 | 9 | 10 |
| 2024 | 3 | 22 | 25 |
| 2025 | 2 | 1 | 3 |
Below are the most recent publications written about "Lymphocytes, Tumor-Infiltrating" by people in Profiles.
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Divergent transcriptional states and kinetics of circulating tumor-infiltrating lymphocyte repertoires with highly homologous T-cell receptor sequences in a patient during immunotherapy. J Immunother Cancer. 2025 Jan 25; 13(1).
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The XCL1-XCR1 axis supports intestinal tissue residency and antitumor immunity. J Exp Med. 2025 Mar 03; 222(2).
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Chemotherapy Drives Tertiary Lymphoid Structures That Correlate with ICI-Responsive TCF1+CD8+ T Cells in Metastatic Ovarian Cancer. Clin Cancer Res. 2025 Jan 06; 31(1):164-180.
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Integrated Germline and Somatic Features Reveal Divergent Immune Pathways Driving Response to Immune Checkpoint Blockade. Cancer Immunol Res. 2024 Dec 03; 12(12):1780-1795.
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Multidimensional Immunotyping of Human NF1-Associated Peripheral Nerve Sheath Tumors Uncovers Tumor-Associated Macrophages as Key Drivers of Immune Evasion in the Tumor Microenvironment. Clin Cancer Res. 2024 Dec 02; 30(23):5459-5472.
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Advances in cell therapy: progress and challenges in hematological and solid tumors. Trends Pharmacol Sci. 2024 Dec; 45(12):1119-1134.
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Mutation burden and anti-PD-1 outcomes are not universally associated with immune cell infiltration or lymphoid activation. Cancer Cell. 2024 Dec 09; 42(12):1985-1987.
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Exploring the therapeutic potential of precision T-Cell Receptors (TCRs) in targeting KRAS G12D cancer through in vitro development. Oncol Res. 2024; 32(12):1837-1850.
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Age-Associated Contraction of Tumor-Specific T Cells Impairs Antitumor Immunity. Cancer Immunol Res. 2024 Nov 04; 12(11):1525-1541.
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Artificial Intelligence-Powered Spatial Analysis of Tumor-Infiltrating Lymphocytes as a Potential Biomarker for Immune Checkpoint Inhibitors in Patients with Biliary Tract Cancer. Clin Cancer Res. 2024 Oct 15; 30(20):4635-4643.