"Spasms, Infantile" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An epileptic syndrome characterized by the triad of infantile spasms, hypsarrhythmia, and arrest of psychomotor development at seizure onset. The majority present between 3-12 months of age, with spasms consisting of combinations of brief flexor or extensor movements of the head, trunk, and limbs. The condition is divided into two forms: cryptogenic (idiopathic) and symptomatic (secondary to a known disease process such as intrauterine infections; nervous system abnormalities; BRAIN DISEASES, METABOLIC, INBORN; prematurity; perinatal asphyxia; TUBEROUS SCLEROSIS; etc.). (From Menkes, Textbook of Child Neurology, 5th ed, pp744-8)
| Descriptor ID |
D013036
|
| MeSH Number(s) |
C10.228.140.490.375.760 C10.228.140.490.493.875
|
| Concept/Terms |
Spasms, Infantile- Spasms, Infantile
- Infantile Spasm
- Infantile Spasms
- Lightning Attacks
- Attack, Lightning
- Attacks, Lightning
- Lightning Attack
- West Syndrome
- Syndrome, West
Jackknife Seizures- Jackknife Seizures
- Jackknife Seizure
- Seizure, Jackknife
- Seizures, Jackknife
Symptomatic Infantile Spasms- Symptomatic Infantile Spasms
- Infantile Spasm, Symptomatic
- Infantile Spasms, Symptomatic
- Spasm, Symptomatic Infantile
- Spasms, Symptomatic Infantile
- Symptomatic Infantile Spasm
- Symptomatic West Syndrome
- Syndrome, Symptomatic West
- West Syndrome, Symptomatic
Salaam Attacks- Salaam Attacks
- Attacks, Salaam
- Salaam Seizures
- Seizures, Salaam
Cryptogenic Infantile Spasms- Cryptogenic Infantile Spasms
- Cryptogenic Infantile Spasm
- Infantile Spasm, Cryptogenic
- Infantile Spasms, Cryptogenic
- Spasm, Cryptogenic Infantile
- Spasms, Cryptogenic Infantile
- Cryptogenic West Syndrome
- Syndrome, Cryptogenic West
- West Syndrome, Cryptogenic
Nodding Spasm- Nodding Spasm
- Nodding Spasms
- Spasm, Nodding
- Spasms, Nodding
|
Below are MeSH descriptors whose meaning is more general than "Spasms, Infantile".
Below are MeSH descriptors whose meaning is more specific than "Spasms, Infantile".
This graph shows the total number of publications written about "Spasms, Infantile" by people in this website by year, and whether "Spasms, Infantile" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 2 | 3 |
| 1996 | 1 | 0 | 1 |
| 1999 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2001 | 2 | 0 | 2 |
| 2002 | 6 | 1 | 7 |
| 2003 | 1 | 1 | 2 |
| 2004 | 3 | 2 | 5 |
| 2005 | 1 | 2 | 3 |
| 2006 | 1 | 1 | 2 |
| 2007 | 4 | 1 | 5 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 1 | 2 |
| 2010 | 1 | 2 | 3 |
| 2011 | 2 | 0 | 2 |
| 2013 | 7 | 0 | 7 |
| 2014 | 3 | 1 | 4 |
| 2015 | 4 | 0 | 4 |
| 2016 | 4 | 0 | 4 |
| 2017 | 10 | 2 | 12 |
| 2018 | 10 | 1 | 11 |
| 2019 | 8 | 1 | 9 |
| 2020 | 15 | 0 | 15 |
| 2021 | 9 | 0 | 9 |
| 2022 | 10 | 1 | 11 |
| 2023 | 9 | 0 | 9 |
| 2024 | 8 | 2 | 10 |
Below are the most recent publications written about "Spasms, Infantile" by people in Profiles.
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Modification of a parent-report sleep scale for individuals with CDKL5 deficiency disorder: a psychometric study. J Clin Sleep Med. 2024 Dec 01; 20(12):1887-1893.
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Deletions in the CDKL5 5' untranslated region lead to CDKL5 deficiency disorder. Am J Med Genet A. 2025 Jan; 197(1):e63843.
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Psychometric evaluation of clinician- and caregiver-reported clinical severity assessments for individuals with CDKL5 deficiency disorder. Epilepsia. 2024 Oct; 65(10):3064-3075.
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Caregiver Perspective of Benefits and Side Effects of Anti-Seizure Medications in CDKL5 Deficiency Disorder from an International Database. CNS Drugs. 2024 Sep; 38(9):719-732.
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A Multicenter Training and Interrater Reliability Study of the BASED Score for Infantile Epileptic Spasms Syndrome. J Clin Neurophysiol. 2025 03 01; 42(3):230-234.
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Effects of ganaxolone on non-seizure outcomes in CDKL5 Deficiency Disorder: Double-blind placebo-controlled randomized trial. Eur J Paediatr Neurol. 2024 Jul; 51:140-146.
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Computational EEG attributes predict response to therapy for epileptic spasms. Clin Neurophysiol. 2024 Jul; 163:39-46.
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Epileptic spasms relapse is associated with response latency but not conventional attributes of post-treatment EEG. Epilepsia Open. 2024 Jun; 9(3):1034-1041.
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Biomimetic Deep Learning Networks With Applications to Epileptic Spasms and Seizure Prediction. IEEE Trans Biomed Eng. 2024 03; 71(3):1056-1067.
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Adapting a measure of gross motor skills for individuals with CDKL5 deficiency disorder: A psychometric study. Epilepsy Res. 2024 Feb; 200:107287.