"Binding Sites, Antibody" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Local surface sites on antibodies which react with antigen determinant sites on antigens (EPITOPES.) They are formed from parts of the variable regions of FAB FRAGMENTS.
| Descriptor ID |
D001666
|
| MeSH Number(s) |
G02.111.570.060.425.079 G02.111.570.120.408 G12.122.232 G12.125
|
| Concept/Terms |
Binding Sites, Antibody- Binding Sites, Antibody
- Antibody Binding Site
- Binding Site, Antibody
- Paratopes
- Paratope
- Antibody Binding Sites
|
Below are MeSH descriptors whose meaning is more general than "Binding Sites, Antibody".
Below are MeSH descriptors whose meaning is more specific than "Binding Sites, Antibody".
This graph shows the total number of publications written about "Binding Sites, Antibody" by people in this website by year, and whether "Binding Sites, Antibody" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 3 | 3 |
| 1996 | 1 | 3 | 4 |
| 1997 | 0 | 5 | 5 |
| 1998 | 0 | 7 | 7 |
| 1999 | 0 | 4 | 4 |
| 2000 | 0 | 5 | 5 |
| 2001 | 1 | 6 | 7 |
| 2002 | 1 | 6 | 7 |
| 2003 | 2 | 3 | 5 |
| 2004 | 0 | 9 | 9 |
| 2005 | 1 | 1 | 2 |
| 2006 | 1 | 6 | 7 |
| 2007 | 1 | 1 | 2 |
| 2008 | 0 | 4 | 4 |
| 2009 | 0 | 4 | 4 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 5 | 6 |
| 2012 | 1 | 5 | 6 |
| 2013 | 0 | 3 | 3 |
| 2014 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 0 | 3 | 3 |
| 2019 | 0 | 1 | 1 |
| 2020 | 1 | 2 | 3 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
Below are the most recent publications written about "Binding Sites, Antibody" by people in Profiles.
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A Paratope-Enhanced Method to Determine Breadth and Depth TCR Clonal Metrics of the Private Human T-Cell Vaccine Response after SARS-CoV-2 Vaccination. Int J Mol Sci. 2023 Sep 18; 24(18).
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Rapid discovery of diverse neutralizing SARS-CoV-2 antibodies from large-scale synthetic phage libraries. MAbs. 2022 Jan-Dec; 14(1):2002236.
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Structural Characterization of a Minimal Antibody against Human APOBEC3B. Viruses. 2021 04 12; 13(4).
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A compact vocabulary of paratope-epitope interactions enables predictability of antibody-antigen binding. Cell Rep. 2021 03 16; 34(11):108856.
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Bi-paratopic and multivalent VH domains block ACE2 binding and neutralize SARS-CoV-2. Nat Chem Biol. 2021 01; 17(1):113-121.
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Multifaceted Effects of Antigen Valency on B Cell Response Composition and Differentiation In Vivo. Immunity. 2020 09 15; 53(3):548-563.e8.
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When two are better than one: Modeling the mechanisms of antibody mixtures. PLoS Comput Biol. 2020 05; 16(5):e1007830.
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Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein. PLoS Pathog. 2020 03; 16(3):e1008373.
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Harnessing Avidity: Quantifying the Entropic and Energetic Effects of Linker Length and Rigidity for Multivalent Binding of Antibodies to HIV-1. Cell Syst. 2019 11 27; 9(5):466-474.e7.
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Engineering Improved Antiphosphotyrosine Antibodies Based on an Immunoconvergent Binding Motif. J Am Chem Soc. 2018 12 05; 140(48):16615-16624.