Cell Transdifferentiation
"Cell Transdifferentiation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A naturally occurring phenomenon where terminally differentiated cells dedifferentiate to the point where they can switch CELL LINEAGES. The cells then differentiate into other cell types.
| Descriptor ID |
D054338
|
| MeSH Number(s) |
G04.356
|
| Concept/Terms |
Cell Transdifferentiation- Cell Transdifferentiation
- Cell Transdifferentiations
- Transdifferentiations, Cell
- Transdifferentiation, Cell
|
Below are MeSH descriptors whose meaning is more general than "Cell Transdifferentiation".
Below are MeSH descriptors whose meaning is more specific than "Cell Transdifferentiation".
This graph shows the total number of publications written about "Cell Transdifferentiation" by people in this website by year, and whether "Cell Transdifferentiation" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2008 | 5 | 6 | 11 |
| 2009 | 8 | 5 | 13 |
| 2010 | 7 | 2 | 9 |
| 2011 | 5 | 2 | 7 |
| 2012 | 8 | 0 | 8 |
| 2013 | 9 | 6 | 15 |
| 2014 | 4 | 5 | 9 |
| 2015 | 6 | 4 | 10 |
| 2016 | 2 | 4 | 6 |
| 2017 | 6 | 8 | 14 |
| 2018 | 6 | 3 | 9 |
| 2019 | 2 | 3 | 5 |
| 2020 | 5 | 3 | 8 |
| 2021 | 2 | 4 | 6 |
| 2022 | 0 | 1 | 1 |
| 2023 | 1 | 1 | 2 |
| 2024 | 1 | 1 | 2 |
Below are the most recent publications written about "Cell Transdifferentiation" by people in Profiles.
-
Long-range Atoh1 enhancers maintain competency for hair cell regeneration in the inner ear. Proc Natl Acad Sci U S A. 2024 Dec 17; 121(51):e2418098121.
-
Adiponectin-induced activation of ERK1/2 drives fibrosis in retinal pigment epithelial cells. Hum Cell. 2024 Oct 26; 38(1):8.
-
Temporal evolution reveals bifurcated lineages in aggressive neuroendocrine small cell prostate cancer trans-differentiation. Cancer Cell. 2023 12 11; 41(12):2066-2082.e9.
-
FoxO1 regulates adipose transdifferentiation and iron influx by mediating Tgfβ1 signaling pathway. Redox Biol. 2023 07; 63:102727.
-
Activation of the EGFR/MAPK pathway drives transdifferentiation of quiescent niche cells to stem cells in the Drosophila testis niche. Elife. 2022 04 25; 11.
-
Human alveolar type 2 epithelium transdifferentiates into metaplastic KRT5+ basal cells. Nat Cell Biol. 2022 01; 24(1):10-23.
-
Programmed genomic instability regulates neural transdifferentiation of human brain microvascular pericytes. Genome Biol. 2021 12 09; 22(1):334.
-
Acinar cell clonal expansion in pancreas homeostasis and carcinogenesis. Nature. 2021 09; 597(7878):715-719.
-
Enhancer decommissioning imposes an epigenetic barrier to sensory hair cell regeneration. Dev Cell. 2021 09 13; 56(17):2471-2485.e5.
-
Upregulation of FGF9 in Lung Adenocarcinoma Transdifferentiation to Small Cell Lung Cancer. Cancer Res. 2021 07 15; 81(14):3916-3929.