"DNA Mismatch Repair" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A DNA repair pathway involved in correction of errors introduced during DNA replication when an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. Excinucleases recognize the BASE PAIR MISMATCH and cause a segment of polynucleotide chain to be excised from the daughter strand, thereby removing the mismatched base. (from Oxford Dictionary of Biochemistry and Molecular Biology, 2001)
| Descriptor ID |
D053843
|
| MeSH Number(s) |
G02.111.222.220 G05.219.220
|
| Concept/Terms |
DNA Mismatch Repair- DNA Mismatch Repair
- Mismatch Repair, DNA
- Repair, DNA Mismatch
- Mismatch Repair
- Repair, Mismatch
|
Below are MeSH descriptors whose meaning is more general than "DNA Mismatch Repair".
Below are MeSH descriptors whose meaning is more specific than "DNA Mismatch Repair".
This graph shows the total number of publications written about "DNA Mismatch Repair" by people in this website by year, and whether "DNA Mismatch Repair" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 2 | 1 | 3 |
| 2007 | 4 | 4 | 8 |
| 2008 | 2 | 5 | 7 |
| 2009 | 3 | 4 | 7 |
| 2010 | 12 | 7 | 19 |
| 2011 | 8 | 3 | 11 |
| 2012 | 5 | 3 | 8 |
| 2013 | 10 | 3 | 13 |
| 2014 | 4 | 5 | 9 |
| 2015 | 10 | 2 | 12 |
| 2016 | 5 | 3 | 8 |
| 2017 | 6 | 4 | 10 |
| 2018 | 11 | 6 | 17 |
| 2019 | 8 | 7 | 15 |
| 2020 | 6 | 5 | 11 |
| 2021 | 6 | 12 | 18 |
| 2022 | 2 | 6 | 8 |
| 2023 | 0 | 7 | 7 |
| 2024 | 4 | 7 | 11 |
| 2025 | 1 | 0 | 1 |
Below are the most recent publications written about "DNA Mismatch Repair" by people in Profiles.
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Pembrolizumab in microsatellite-instability-high and mismatch-repair-deficient advanced solid tumors: updated results of the KEYNOTE-158 trial. Nat Cancer. 2025 Feb; 6(2):253-258.
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The landscape of primary mismatch repair deficient gliomas in children, adolescents, and young adults: a multi-cohort study. Lancet Oncol. 2025 Jan; 26(1):123-135.
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Nivolumab plus Ipilimumab in Microsatellite-Instability-High Metastatic Colorectal Cancer. N Engl J Med. 2024 Nov 28; 391(21):2014-2026.
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Analysis of Concordance Between Next-Generation Sequencing Assessment of Microsatellite Instability and Immunohistochemistry-Mismatch Repair From Solid Tumors. JCO Precis Oncol. 2024 Oct; 8:e2300648.
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MSH6-proficient crypt foci in MSH6 constitutional mismatch repair deficiency: reversion of a frameshifted coding microsatellite to its wild-type sequence. Fam Cancer. 2024 Nov; 23(4):569-577.
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The Proteogenomics of Prostate Cancer Radioresistance. Cancer Res Commun. 2024 09 01; 4(9):2463-2479.
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Somatic CpG hypermutation is associated with mismatch repair deficiency in cancer. Mol Syst Biol. 2024 Sep; 20(9):1006-1024.
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Differential Responses to Immune Checkpoint Inhibitors are Governed by Diverse Mismatch Repair Gene Alterations. Clin Cancer Res. 2024 May 01; 30(9):1906-1915.
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Somatic Mutations in Surgically Treated Colorectal Liver Metastases: An Overview. Cells. 2024 04 14; 13(8).
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Clinical and biological landscape of constitutional mismatch-repair deficiency syndrome: an International Replication Repair Deficiency Consortium cohort study. Lancet Oncol. 2024 May; 25(5):668-682.