"Terfenadine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.
| Descriptor ID |
D016593
|
| MeSH Number(s) |
D02.455.426.559.389.115.800 D03.383.621.855
|
| Concept/Terms |
Terfenadine- Terfenadine
- Terfenidine
- alpha-(4-(1,1-Dimethylethyl)phenyl)-4-(hydroxydiphenylmethyl)-1-piperdinebutanol
|
Below are MeSH descriptors whose meaning is more general than "Terfenadine".
Below are MeSH descriptors whose meaning is more specific than "Terfenadine".
This graph shows the total number of publications written about "Terfenadine" by people in this website by year, and whether "Terfenadine" was a major or minor topic of these publications.
Below are the most recent publications written about "Terfenadine" by people in Profiles.
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Fexofenadine Plasma Concentrations to Estimate Systemic Exposure in Healthy Adults Using a Limited Sampling Strategy with a Population Pharmacokinetic Approach. Ther Drug Monit. 2023 08 01; 45(4):539-545.
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Bacterial metabolism rescues the inhibition of intestinal drug absorption by food and drug additives. Proc Natl Acad Sci U S A. 2020 07 07; 117(27):16009-16018.
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Cosmetic tattoo pigment reaction. Dermatol Online J. 2016 Jul 15; 22(7).
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In silico screening of the impact of hERG channel kinetic abnormalities on channel block and susceptibility to acquired long QT syndrome. J Mol Cell Cardiol. 2014 Jul; 72:126-37.
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Ketoconazole-associated preferential increase in dopamine D2 receptor occupancy in striatum compared to pituitary in vivo: role for drug transporters? J Clin Psychopharmacol. 2012 Feb; 32(1):110-3.
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Pharmacophore modeling for hERG channel facilitation. Biochem Biophys Res Commun. 2012 Feb 03; 418(1):161-6.
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Evaluation of in vivo P-glycoprotein phenotyping probes: a need for validation. Clin Pharmacokinet. 2010 Apr; 49(4):223-37.
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Narrowband ultraviolet B phototherapy is beneficial in antihistamine-resistant symptomatic dermographism: a pilot study. J Am Acad Dermatol. 2008 Nov; 59(5):752-7.
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Probenecid, but not cystic fibrosis, alters the total and renal clearance of fexofenadine. J Clin Pharmacol. 2008 Aug; 48(8):957-65.
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Lack of action potential-prolonging effect of terfenadine on rabbit myocardial tissue preparations. Biol Pharm Bull. 2004 Jan; 27(1):131-5.