Voltage-Gated Sodium Channels
"Voltage-Gated Sodium Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of membrane proteins that selectively conduct SODIUM ions due to changes in the TRANSMEMBRANE POTENTIAL DIFFERENCE. They typically have a multimeric structure with a core alpha subunit that defines the sodium channel subtype and several beta subunits that modulate sodium channel activity.
| Descriptor ID |
D061566
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| MeSH Number(s) |
D12.776.157.530.400.875.750 D12.776.543.550.450.875.750 D12.776.543.585.400.875.750 D12.776.631.960
|
| Concept/Terms |
Voltage-Gated Sodium Channels- Voltage-Gated Sodium Channels
- Channels, Voltage-Gated Sodium
- Voltage Gated Sodium Channels
- Sodium Channels, Voltage-Gated
- Sodium Channels, Voltage Gated
|
Below are MeSH descriptors whose meaning is more general than "Voltage-Gated Sodium Channels".
Below are MeSH descriptors whose meaning is more specific than "Voltage-Gated Sodium Channels".
This graph shows the total number of publications written about "Voltage-Gated Sodium Channels" by people in this website by year, and whether "Voltage-Gated Sodium Channels" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2012 | 1 | 4 | 5 |
| 2013 | 2 | 2 | 4 |
| 2014 | 6 | 1 | 7 |
| 2015 | 1 | 3 | 4 |
| 2016 | 3 | 1 | 4 |
| 2017 | 2 | 1 | 3 |
| 2019 | 2 | 1 | 3 |
| 2020 | 5 | 1 | 6 |
| 2021 | 5 | 0 | 5 |
| 2022 | 2 | 0 | 2 |
| 2023 | 1 | 0 | 1 |
| 2024 | 0 | 1 | 1 |
| 2025 | 0 | 1 | 1 |
Below are the most recent publications written about "Voltage-Gated Sodium Channels" by people in Profiles.
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Differential encoding of mammalian proprioception by voltage-gated sodium channels. Sci Adv. 2025 Jan 10; 11(2):eads6660.
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A self-eliminating allelic-drive reverses insecticide resistance in Drosophila leaving no transgene in the population. Nat Commun. 2024 Nov 17; 15(1):9961.
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LRRC37B is a human modifier of voltage-gated sodium channels and axon excitability in cortical neurons. Cell. 2023 12 21; 186(26):5766-5783.e25.
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Regulating voltage-gated ion channels with nanobodies. Nat Commun. 2022 Dec 09; 13(1):7557.
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Quaternary structure independent folding of voltage-gated ion channel pore domain subunits. Nat Struct Mol Biol. 2022 06; 29(6):537-548.
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Differential effects of modified batrachotoxins on voltage-gated sodium channel fast and slow inactivation. Cell Chem Biol. 2022 04 21; 29(4):615-624.e5.
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Developmental dynamics of voltage-gated sodium channel isoform expression in the human and mouse brain. Genome Med. 2021 08 23; 13(1):135.
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Rate-dependent effects of lidocaine on cardiac dynamics: Development and analysis of a low-dimensional drug-channel interaction model. PLoS Comput Biol. 2021 06; 17(6):e1009145.
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Enhanced excitability of cortical neurons in low-divalent solutions is primarily mediated by altered voltage-dependence of voltage-gated sodium channels. Elife. 2021 05 11; 10.
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Venom-Derived Peptides Inhibiting Voltage-Gated Sodium and Calcium Channels in Mammalian Sensory Neurons. Adv Exp Med Biol. 2021; 1349:3-19.