"Interleukin-10" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytokine produced by a variety of cell types, including T-LYMPHOCYTES; MONOCYTES; DENDRITIC CELLS; and EPITHELIAL CELLS that exerts a variety of effects on immunoregulation and INFLAMMATION. Interleukin-10 combines with itself to form a homodimeric molecule that is the biologically active form of the protein.
| Descriptor ID |
D016753
|
| MeSH Number(s) |
D12.644.276.374.465.510 D12.776.467.374.465.510 D23.529.374.465.510
|
| Concept/Terms |
Interleukin-10- Interleukin-10
- Interleukin 10
- IL10
- IL-10
- CSIF-10
- Cytokine Synthesis Inhibitory Factor
|
Below are MeSH descriptors whose meaning is more general than "Interleukin-10".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-10".
This graph shows the total number of publications written about "Interleukin-10" by people in this website by year, and whether "Interleukin-10" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 5 | 6 |
| 1996 | 6 | 12 | 18 |
| 1997 | 7 | 5 | 12 |
| 1998 | 12 | 5 | 17 |
| 1999 | 10 | 14 | 24 |
| 2000 | 14 | 16 | 30 |
| 2001 | 7 | 10 | 17 |
| 2002 | 11 | 9 | 20 |
| 2003 | 12 | 20 | 32 |
| 2004 | 12 | 18 | 30 |
| 2005 | 11 | 10 | 21 |
| 2006 | 10 | 23 | 33 |
| 2007 | 9 | 15 | 24 |
| 2008 | 6 | 18 | 24 |
| 2009 | 13 | 19 | 32 |
| 2010 | 11 | 25 | 36 |
| 2011 | 8 | 29 | 37 |
| 2012 | 16 | 18 | 34 |
| 2013 | 18 | 22 | 40 |
| 2014 | 24 | 27 | 51 |
| 2015 | 11 | 25 | 36 |
| 2016 | 15 | 18 | 33 |
| 2017 | 9 | 16 | 25 |
| 2018 | 11 | 14 | 25 |
| 2019 | 7 | 12 | 19 |
| 2020 | 11 | 8 | 19 |
| 2021 | 7 | 10 | 17 |
| 2022 | 9 | 19 | 28 |
| 2023 | 4 | 11 | 15 |
| 2024 | 6 | 10 | 16 |
| 2025 | 1 | 0 | 1 |
Below are the most recent publications written about "Interleukin-10" by people in Profiles.
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Fluoxetine promotes IL-10-dependent metabolic defenses to protect from sepsis-induced lethality. Sci Adv. 2025 Feb 14; 11(7):eadu4034.
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Pathobiont-induced suppressive immune imprints thwart T cell vaccine responses. Nat Commun. 2024 Dec 16; 15(1):10335.
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Pathobiont-driven antibody sialylation through IL-10 undermines vaccination. J Clin Invest. 2024 Dec 16; 134(24).
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Programming tissue-sensing T cells that deliver therapies to the brain. Science. 2024 Dec 06; 386(6726):eadl4237.
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Engineering synthetic suppressor T cells that execute locally targeted immunoprotective programs. Science. 2024 Dec 06; 386(6726):eadl4793.
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Exclusive enteral nutrition initiates individual protective microbiome changes to induce remission in pediatric Crohn's disease. Cell Host Microbe. 2024 Nov 13; 32(11):2019-2034.e8.
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Differential inflammatory profiles in carriers of reciprocal 22q11.2 copy number variants. Psychoneuroendocrinology. 2024 Nov; 169:107135.
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IL-10 suppresses T cell expansion while promoting tissue-resident memory cell formation during SARS-CoV-2 infection in rhesus macaques. PLoS Pathog. 2024 Jul; 20(7):e1012339.
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Profiling phagosome proteins identifies PD-L1 as a fungal-binding receptor. Nature. 2024 Jun; 630(8017):736-743.
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Integrated transcriptomic analysis reveals immune signatures distinguishing persistent versus resolving outcomes in MRSA bacteremia. Front Immunol. 2024; 15:1373553.