"Spectrin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A high molecular weight (220-250 kDa) water-soluble protein which can be extracted from erythrocyte ghosts in low ionic strength buffers. The protein contains no lipids or carbohydrates, is the predominant species of peripheral erythrocyte membrane proteins, and exists as a fibrous coating on the inner, cytoplasmic surface of the membrane.
| Descriptor ID |
D013049
|
| MeSH Number(s) |
D12.776.220.980 D12.776.543.850
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Spectrin".
Below are MeSH descriptors whose meaning is more specific than "Spectrin".
This graph shows the total number of publications written about "Spectrin" by people in this website by year, and whether "Spectrin" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 3 | 1 | 4 |
| 1996 | 1 | 1 | 2 |
| 1997 | 1 | 2 | 3 |
| 1998 | 1 | 2 | 3 |
| 2000 | 2 | 0 | 2 |
| 2001 | 1 | 0 | 1 |
| 2002 | 0 | 2 | 2 |
| 2003 | 0 | 5 | 5 |
| 2004 | 0 | 1 | 1 |
| 2005 | 3 | 1 | 4 |
| 2006 | 1 | 1 | 2 |
| 2007 | 1 | 1 | 2 |
| 2008 | 1 | 1 | 2 |
| 2009 | 1 | 2 | 3 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 1 | 2 |
| 2012 | 1 | 2 | 3 |
| 2013 | 1 | 3 | 4 |
| 2014 | 1 | 1 | 2 |
| 2015 | 1 | 4 | 5 |
| 2016 | 1 | 0 | 1 |
| 2017 | 2 | 1 | 3 |
| 2018 | 1 | 0 | 1 |
| 2021 | 1 | 1 | 2 |
| 2022 | 1 | 1 | 2 |
| 2023 | 0 | 1 | 1 |
| 2024 | 1 | 0 | 1 |
Below are the most recent publications written about "Spectrin" by people in Profiles.
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Mechanically induced topological transition of spectrin regulates its distribution in the mammalian cell cortex. Nat Commun. 2024 Jul 08; 15(1):5711.
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Hypothermia Treatment after Hypoxia-Ischemia in Glutathione Peroxidase-1 Overexpressing Mice. Dev Neurosci. 2024; 46(2):98-111.
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βIV-Spectrin Autoantibodies in 2 Individuals With Neuropathy of Possible Paraneoplastic Origin: A Case Series. Neurol Neuroimmunol Neuroinflamm. 2022 07; 9(4).
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Nanoscale dynamics of actin filaments in the red blood cell membrane skeleton. Mol Biol Cell. 2022 03 01; 33(3):ar28.
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β2-spectrin (SPTBN1) as a therapeutic target for diet-induced liver disease and preventing cancer development. Sci Transl Med. 2021 12 15; 13(624):eabk2267.
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Pathogenic SPTBN1 variants cause an autosomal dominant neurodevelopmental syndrome. Nat Genet. 2021 07; 53(7):1006-1021.
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Glial βII Spectrin Contributes to Paranode Formation and Maintenance. J Neurosci. 2018 07 04; 38(27):6063-6075.
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Spectrin is a mechanoresponsive protein shaping fusogenic synapse architecture during myoblast fusion. Nat Cell Biol. 2018 06; 20(6):688-698.
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Hereditary elliptocytosis: Variable clinical severity caused by 3 variants in the α-spectrin gene. Int J Lab Hematol. 2018 08; 40(4):e66-e70.
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αII-spectrin and βII-spectrin do not affect TGFβ1-induced myofibroblast differentiation. Cell Tissue Res. 2018 Oct; 374(1):165-175.