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Plasminogen

"Plasminogen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

expand / collapse MeSH information
Precursor of plasmin (FIBRINOLYSIN). It is a single-chain beta-globulin of molecular weight 80-90,000 found mostly in association with fibrinogen in plasma; plasminogen activators change it to fibrinolysin. It is used in wound debriding and has been investigated as a thrombolytic agent.


expand / collapse Publications
This graph shows the total number of publications written about "Plasminogen" by people in this website by year, and whether "Plasminogen" was a major or minor topic of these publications.
Below are the most recent publications written about "Plasminogen" by people in Profiles.
  1. Dysregulated fibrinolysis and plasmin activation promote the pathogenesis of osteoarthritis. JCI Insight. 2024 Mar 19; 9(8).
    View in: PubMed
  2. Liver-derived plasminogen mediates muscle stem cell expansion during caloric restriction through the plasminogen receptor Plg-RKT. Cell Rep. 2024 03 26; 43(3):113881.
    View in: PubMed
  3. Atherothrombotic and thrombolytic biomarkers in incident stroke and atrial fibrillation-related stroke: The Multi-Ethnic Study of Atherosclerosis (MESA). Atherosclerosis. 2024 03; 390:117451.
    View in: PubMed
  4. Overexpression of Plg-RKT protects against adipose dysfunction and dysregulation of glucose homeostasis in diet-induced obese mice. Adipocyte. 2023 12; 12(1):2252729.
    View in: PubMed
  5. Plasminogen deficiency suppresses pancreatic ductal adenocarcinoma disease progression. Mol Oncol. 2024 Jan; 18(1):113-135.
    View in: PubMed
  6. Plasmin and plasminogen prevent sepsis severity by reducing neutrophil extracellular traps and systemic inflammation. JCI Insight. 2023 04 24; 8(8).
    View in: PubMed
  7. Oxidized phospholipids on apolipoprotein B-100 versus plasminogen and risk of coronary heart disease in the PROCARDIS study. Atherosclerosis. 2022 08; 354:15-22.
    View in: PubMed
  8. Plg-RKT Expression in Human Breast Cancer Tissues. Biomolecules. 2022 03 26; 12(4).
    View in: PubMed
  9. Fibrin is a critical regulator of neutrophil effector function at the oral mucosal barrier. Science. 2021 Dec 24; 374(6575):eabl5450.
    View in: PubMed
  10. The plasminogen receptor Plg-RKT regulates adipose function and metabolic homeostasis. J Thromb Haemost. 2022 03; 20(3):742-754.
    View in: PubMed