"Drug Resistance" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Diminished or failed response of an organism, disease or tissue to the intended effectiveness of a chemical or drug. It should be differentiated from DRUG TOLERANCE which is the progressive diminution of the susceptibility of a human or animal to the effects of a drug, as a result of continued administration.
| Descriptor ID |
D004351
|
| MeSH Number(s) |
G07.690.773.984
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Drug Resistance".
Below are MeSH descriptors whose meaning is more specific than "Drug Resistance".
This graph shows the total number of publications written about "Drug Resistance" by people in this website by year, and whether "Drug Resistance" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 18 | 18 |
| 1996 | 0 | 14 | 14 |
| 1997 | 0 | 9 | 9 |
| 1998 | 1 | 15 | 16 |
| 1999 | 0 | 21 | 21 |
| 2000 | 1 | 15 | 16 |
| 2001 | 2 | 19 | 21 |
| 2002 | 5 | 20 | 25 |
| 2003 | 2 | 22 | 24 |
| 2004 | 5 | 19 | 24 |
| 2005 | 10 | 19 | 29 |
| 2006 | 11 | 29 | 40 |
| 2007 | 10 | 11 | 21 |
| 2008 | 10 | 19 | 29 |
| 2009 | 15 | 26 | 41 |
| 2010 | 13 | 39 | 52 |
| 2011 | 15 | 23 | 38 |
| 2012 | 5 | 31 | 36 |
| 2013 | 10 | 30 | 40 |
| 2014 | 16 | 29 | 45 |
| 2015 | 15 | 16 | 31 |
| 2016 | 13 | 21 | 34 |
| 2017 | 16 | 22 | 38 |
| 2018 | 12 | 22 | 34 |
| 2019 | 14 | 28 | 42 |
| 2020 | 12 | 15 | 27 |
| 2021 | 9 | 17 | 26 |
| 2022 | 2 | 13 | 15 |
| 2023 | 2 | 12 | 14 |
| 2024 | 12 | 7 | 19 |
| 2025 | 0 | 1 | 1 |
Below are the most recent publications written about "Drug Resistance" by people in Profiles.
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Renal Denervation Effects on Blood Pressure in Resistant and Uncontrolled Hypertension: A Meta-Analysis of Sham-Controlled Randomized Clinical Trials. Clin Cardiol. 2025 Mar; 48(3):e70104.
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Systematic in vitro evolution in Plasmodium falciparum reveals key determinants of drug resistance. Science. 2024 Nov 29; 386(6725):eadk9893.
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Plasmodium falciparum molecular surveillance to inform the Mozambican National Malaria Control Programme strategy: protocol. BMJ Open. 2024 Nov 24; 14(11):e092590.
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The extended recovery ring-stage survival assay is a scalable alternative for artemisinin susceptibility phenotyping of fresh Plasmodium falciparum isolates. Antimicrob Agents Chemother. 2024 Dec 05; 68(12):e0118324.
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Exploration and characterization of the antimalarial activity of cyclopropyl carboxamides that target the mitochondrial protein, cytochrome b. Eur J Med Chem. 2024 Dec 15; 280:116921.
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A Multicenter Evaluation of Clopidogrel Resistance and Its Role in Predicting Stent Thrombosis in Transcarotid Artery Revascularization. Ann Vasc Surg. 2025 Jan; 110(Pt A):226-232.
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FCGR2/3 polymorphisms are associated with susceptibility to Kawasaki disease but do not predict intravenous immunoglobulin resistance and coronary artery aneurysms. Front Immunol. 2024; 15:1323171.
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Ex vivo susceptibilities to ganaplacide and diversity in potential resistance mediators in Ugandan Plasmodium falciparum isolates. Antimicrob Agents Chemother. 2024 09 04; 68(9):e0046624.
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Simultaneous Intravitreal Steroid and Anti-VEGF Therapy for Monotherapy-Resistant Chronic Wet Age-Related Macular Degeneration. Ophthalmic Surg Lasers Imaging Retina. 2024 Dec; 55(12):698-704.
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Artemisinin-resistant malaria in Africa demands urgent action. Science. 2024 Jul 19; 385(6706):252-254.