SPiCCAto
Software developed to study the influence of the extracellular matrix in cell migration.
Software PaCkage for Cell reseArch
This project is hosted by the CFisUC at the University of Coimbra and consists in a phase-field model for multicellular systems.
This software was developed to study how the mechanical constraints imposed by the extracellular matrix (ECM) affect cell migration. We explored a phase-field model that describes the fibres and the cell as order parameters that interact by repulsion and adhesion.
Publications
M. Moreira-Soares, S. Pinto-Cunha, J. R. Bordin, R. D. M. Travasso. “Adhesion modulates cell morphology and migration within dense fibrous networks”. https://doi.org/10.1101/838995
