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Swaminathan et al., 2021 - Google Patents

RNA interference and nanotechnology: A promising alliance for next generation cancer therapeutics

Swaminathan et al., 2021

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Document ID
999285678552033562
Author
Swaminathan G
Shigna A
Kumar A
Byroju V
Durgempudi V
Dinesh Kumar L
Publication year
Publication venue
Frontiers in Nanotechnology

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Snippet

Cancer is a significant health hazard of the 21st century, and GLOBOCAN predicts increasing cancer incidence in the coming decades. Though several conventional treatment modalities exist, most of them end up causing off-target and debilitating effects, and drug …
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering N.A.
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    • C12N15/111—General methods applicable to biologically active non-coding nucleic acids
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